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Neuromuscular respiratory weakness also leads to ineffective cough and retained airways secretions, predisposing to recurrent chest infections. In this review, we discuss current practice and recent developments in the respiratory management of motor neurone disease, in terms of ventilatory support and cough augmentation.<\/jats:p>","DOI":"10.1136\/practneurol-2011-000199","type":"journal-article","created":{"date-parts":[[2012,6,1]],"date-time":"2012-06-01T04:48:07Z","timestamp":1338526087000},"page":"166-176","source":"Crossref","is-referenced-by-count":20,"title":["Respiratory management of motor neurone disease: a review of current practice and new developments"],"prefix":"10.1136","volume":"12","author":[{"given":"Muhammad Khizar","family":"Rafiq","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alison Ruth","family":"Proctor","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christopher J","family":"McDermott","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pamela J","family":"Shaw","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2012,6,1]]},"reference":[{"key":"2025090411582443000_12.3.166.1","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1016\/S0272-5231(21)00956-4","article-title":"Central control of ventilation in neuromuscular disease","volume":"15","author":"Johnson","year":"1994","journal-title":"Clin Chest Med"},{"key":"2025090411582443000_12.3.166.2","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.02.01302001a"},{"key":"2025090411582443000_12.3.166.3","first-page":"51","article-title":"(Respiratory form of onset of motor neuron disease)","volume":"30","author":"Tall\u00f3n-Barranco","year":"2000","journal-title":"Rev Neurol"},{"key":"2025090411582443000_12.3.166.4","doi-asserted-by":"crossref","unstructured":"Radunovic A Annane D Jewitt K . 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