{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T17:53:26Z","timestamp":1757613206020,"version":"3.44.0"},"reference-count":12,"publisher":"BMJ","issue":"5","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["Pract Neurol"],"published-print":{"date-parts":[[2014,10]]},"abstract":"<jats:p>\n                  <jats:italic>Gloriosa superba<\/jats:italic>, a flowering plant widespread in South and Southeast Asia, is implicated in many cases of self-poisoning. Colchicine is concentrated in the seeds and tubers and this mediates its toxicity. We describe a 28-year-old woman who developed delayed encephalopathy after eating <jats:italic>G superba<\/jats:italic> tubers. MR scan of brain showed bilateral symmetrical T2 basal ganglia hyperintensities in the caudate and lentiform nuclei. The delay in onset of encephalopathy is attributable to a direct-effect colchicine, probably mediated through its effect on microtubular transport.<\/jats:p>","DOI":"10.1136\/practneurol-2013-000753","type":"journal-article","created":{"date-parts":[[2014,3,4]],"date-time":"2014-03-04T00:35:55Z","timestamp":1393893355000},"page":"357-359","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":7,"title":["Toxic encephalopathy due to colchicine\u2014<i>Gloriosa superba<\/i> poisoning"],"prefix":"10.1136","volume":"14","author":[{"given":"Inuka Kishara","family":"Gooneratne","sequence":"first","affiliation":[{"name":"Institute of Neurology, National Hospital of Sri Lanka, Colombo, Sri Lanka"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Praveen","family":"Weeratunga","sequence":"additional","affiliation":[{"name":"University Medical Unit, National Hospital of Sri Lanka, Panadura, Sri Lanka"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manjula","family":"Caldera","sequence":"additional","affiliation":[{"name":"Institute of Neurology, National Hospital of Sri Lanka, Colombo, Sri Lanka"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ranjanie","family":"Gamage","sequence":"additional","affiliation":[{"name":"Institute of Neurology, National Hospital of Sri Lanka, Colombo, Sri Lanka"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2014,3,3]]},"reference":[{"key":"2025090410594440000_14.5.357.1","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1016\/j.fitote.2010.11.008","article-title":"Critical review on medicinally potent plant species: Gloriosa superba","volume":"82","author":"Jana","year":"2011","journal-title":"Fitoterapia"},{"key":"2025090410594440000_14.5.357.2","first-page":"579","article-title":"Poisoning with plants and mushrooms in Sri Lanka: a retrospective hospital based study","volume":"32","author":"Fernando","year":"1990","journal-title":"Vet Hum Toxicol"},{"key":"2025090410594440000_14.5.357.3","first-page":"1","article-title":"Analysis of alkaloids in Gloriosa superba","volume":"17","author":"Dunuwille","year":"1968","journal-title":"Ceylon J Med Sci"},{"key":"2025090410594440000_14.5.357.4","doi-asserted-by":"publisher","DOI":"10.1136\/pgmj.65.768.752"},{"key":"2025090410594440000_14.5.357.5","first-page":"210","article-title":"Review: current advances in Gloriosa superba L","volume":"10.4","author":"Ade","year":"2009","journal-title":"Biodiversitas"},{"key":"2025090410594440000_14.5.357.6","doi-asserted-by":"crossref","first-page":"1562","DOI":"10.1056\/NEJM198706183162502","article-title":"Colchicine myopathy and neuropathy","volume":"316","author":"Kuncl","year":"1987","journal-title":"N Engl J Med"},{"key":"2025090410594440000_14.5.357.7","doi-asserted-by":"publisher","DOI":"10.1136\/pmj.77.905.191"},{"key":"2025090410594440000_14.5.357.8","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.1965.03860130031005"},{"key":"2025090410594440000_14.5.357.9","doi-asserted-by":"publisher","DOI":"10.1016\/S0196-0644(81)80239-9"},{"key":"2025090410594440000_14.5.357.10","first-page":"21","article-title":"Delayed neurological deterioration following hypoxia","volume":"26","author":"Ginsberg","year":"1979","journal-title":"Adv Neurol"},{"key":"2025090410594440000_14.5.357.11","doi-asserted-by":"publisher","DOI":"10.1148\/rg.311105041"},{"key":"2025090410594440000_14.5.357.12","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/0024-3205(84)90150-4","article-title":"Neurotoxicity of colchicine and other tubulin-binding agents: a selective vulnerability of certain neurons to the disruption of microtubules","volume":"35","author":"Steward","year":"1984","journal-title":"Life Sci"}],"container-title":["Practical Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/practneurol-2013-000753","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,4]],"date-time":"2025-09-04T18:02:39Z","timestamp":1757008959000},"score":1,"resource":{"primary":{"URL":"https:\/\/pn.bmj.com\/lookup\/doi\/10.1136\/practneurol-2013-000753"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,3,3]]},"references-count":12,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2014,9,9]]},"published-print":{"date-parts":[[2014,10]]}},"alternative-id":["10.1136\/practneurol-2013-000753"],"URL":"https:\/\/doi.org\/10.1136\/practneurol-2013-000753","relation":{},"ISSN":["1474-7758","1474-7766"],"issn-type":[{"type":"print","value":"1474-7758"},{"type":"electronic","value":"1474-7766"}],"subject":[],"published":{"date-parts":[[2014,3,3]]}}}