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These are conditions with the potential to be either underdiagnosed when not considered or overdiagnosed if there is an equivocal L-dopa (levo-3,4-dihydroxyphenylalanine) response. In this article, we discuss the clinical phenotypes of these disorders, and we outline how investigations can help in confirming the diagnosis.<\/jats:p>","DOI":"10.1136\/practneurol-2015-001101","type":"journal-article","created":{"date-parts":[[2015,6,4]],"date-time":"2015-06-04T23:10:24Z","timestamp":1433459424000},"page":"340-345","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":23,"title":["Diagnosing dopamine-responsive dystonias"],"prefix":"10.1136","volume":"15","author":[{"given":"N","family":"Malek","sequence":"first","affiliation":[{"name":"Department of Neurology, Institute of Neurological Sciences, Southern General Hospital, Glasgow, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N","family":"Fletcher","sequence":"additional","affiliation":[{"name":"Department of Neurology, Walton Centre NHS Foundation Trust, Liverpool, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E","family":"Newman","sequence":"additional","affiliation":[{"name":"Department of Neurology, Institute of Neurological Sciences, Southern General Hospital, Glasgow, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2015,6,4]]},"reference":[{"key":"2025090411471174000_15.5.340.1","first-page":"215","article-title":"Hereditary progressive dystonia with marked diurnal fluctuation","volume":"14","author":"Segawa","year":"1976","journal-title":"Adv Neurol"},{"key":"2025090411471174000_15.5.340.2","first-page":"377","article-title":"Dopa-responsive dystonia","volume":"50","author":"Nygaard","year":"1988","journal-title":"Adv Neurol"},{"key":"2025090411471174000_15.5.340.3","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410300106"},{"key":"2025090411471174000_15.5.340.4","first-page":"577","article-title":"Dopa-responsive dystonia. 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