{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,2]],"date-time":"2026-11-02T16:32:00Z","timestamp":1793637120373,"version":"4.5.1"},"reference-count":2,"publisher":"BMJ","issue":"1","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["Pract Neurol"],"accepted":{"date-parts":[[2016,10,13]]},"published-print":{"date-parts":[[2017,2]]},"abstract":"<jats:p>We describe a rare neurological presentation of internal jugular vein thrombosis induced by central venous catheter placement in a patient with cancer. A 71-year-old man gave a 3-week history of dysphagia and dysarthria with left-sided neck pain and headache. He was receiving chemotherapy for appendiceal adenocarcinoma. On examination, he had left 9th\u201312th cranial neuropathies, manifesting as voice hoarseness, decreased palatal movement, absent gag reflex, weakness of scapular elevation and left-sided tongue wasting. CT scan of neck showed the left subclavian central venous catheter tip was in the left internal jugular vein. Skull base MRI showed thrombus within the left jugular foramen extending intracranially. We diagnosed Collet-Sicard syndrome secondary to thrombosis in the sigmoid\u2013jugular venous complex. His headache and neck pain resolved 2\u2005days after removing the catheter and starting anticoagulation. Collet-Sicard syndrome is an unusual syndrome of lower cranial nerve palsies, often signifying disease at the skull base, including malignancy, trauma or vascular causes.<\/jats:p>","DOI":"10.1136\/practneurol-2015-001268","type":"journal-article","created":{"date-parts":[[2016,11,3]],"date-time":"2016-11-03T22:09:22Z","timestamp":1478210962000},"page":"63-65","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":18,"title":["Collet-Sicard syndrome: a rare but important presentation of internal jugular vein thrombosis"],"prefix":"10.1136","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3362-2717","authenticated-orcid":false,"given":"Shermyn","family":"Neo","sequence":"first","affiliation":[{"name":"Department of Neurology, National Neuroscience Institute, Tan Tock Seng Hospital, Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kim En","family":"Lee","sequence":"additional","affiliation":[{"name":"Mount Elizabeth Medical Centre, Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2016,11,3]]},"reference":[{"key":"2025090410493198000_17.1.63.1","doi-asserted-by":"crossref","first-page":"pii:203587","DOI":"10.1155\/2010\/203587","article-title":"Collet-Sicard syndrome from thrombosis of the sigmoid-jugular complex: a case report and review of the literature","volume":"2010","author":"Handley","year":"2010","journal-title":"Int J Otolaryngol"},{"key":"2025090410493198000_17.1.63.2","doi-asserted-by":"publisher","DOI":"10.1634\/theoncologist.9-2-207"}],"container-title":["Practical Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/practneurol-2015-001268","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,4]],"date-time":"2025-09-04T17:49:41Z","timestamp":1757008181000},"score":1,"resource":{"primary":{"URL":"https:\/\/pn.bmj.com\/lookup\/doi\/10.1136\/practneurol-2015-001268"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,11,3]]},"references-count":2,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2017,1,17]]},"published-print":{"date-parts":[[2017,2]]}},"alternative-id":["10.1136\/practneurol-2015-001268"],"URL":"https:\/\/doi.org\/10.1136\/practneurol-2015-001268","relation":{},"ISSN":["1474-7758","1474-7766"],"issn-type":[{"value":"1474-7758","type":"print"},{"value":"1474-7766","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,11,3]]}}}