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Invasive procedures include occipital nerve stimulation, sphenopalatine ganglion stimulation and ventral tegmental area deep brain stimulation. These stimulation devices may find a place in the treatment pathway of headache disorders. Here, we explore the basic principles of neurostimulation for headache and overview the available methods of neurostimulation.<\/jats:p>","DOI":"10.1136\/practneurol-2015-001298","type":"journal-article","created":{"date-parts":[[2016,9,14]],"date-time":"2016-09-14T00:59:03Z","timestamp":1473814743000},"page":"362-375","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":54,"title":["Neurostimulation in the treatment of primary headaches"],"prefix":"10.1136","volume":"16","author":[{"given":"Sarah","family":"Miller","sequence":"first","affiliation":[{"name":"Headache Group, Institute of Neurology and The National Hospital for Neurology and Neurosurgery, London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alex J","family":"Sinclair","sequence":"additional","affiliation":[{"name":"Neurometabolism, Institute of Metabolism and Systems Research, College of Medical and Dental Sciences, The University of Birmingham, Birmingham, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brendan","family":"Davies","sequence":"additional","affiliation":[{"name":"Department of Neurology, Royal Stoke University Hospital, Stoke-on-Trent, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manjit","family":"Matharu","sequence":"additional","affiliation":[{"name":"Headache Group, Institute of Neurology and The National Hospital for Neurology and Neurosurgery, London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2016,5,5]]},"reference":[{"key":"2025090410291140000_16.5.362.1","unstructured":"World Health Organisation. 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