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We suggest three points to aid the recognition of seizures involving the insula: (1) Seizures originating in the insula frequently present with a sensation of laryngeal constriction, dyspnoea or unpleasant somatosensory symptoms; (2) Seizures involving the anterior insula may have a silent onset, but tend to propagate rapidly to motor areas causing motor or hypermotor symptoms; (3) Seizures involving the posterior insula cause somatosensory symptoms, which are normally contralateral to the seizure onset.<\/jats:p>","DOI":"10.1136\/practneurol-2016-001493","type":"journal-article","created":{"date-parts":[[2016,12,14]],"date-time":"2016-12-14T20:40:21Z","timestamp":1481748021000},"page":"122-126","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":9,"title":["Navigating the Island of Reil: how to understand the insular cortex"],"prefix":"10.1136","volume":"17","author":[{"given":"Ray","family":"Wynford-Thomas","sequence":"first","affiliation":[{"name":"Department of Neurology, Morriston Hospital, Swansea, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rob","family":"Powell","sequence":"additional","affiliation":[{"name":"Department of Neurology, Morriston Hospital, Swansea, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2016,12,14]]},"reference":[{"key":"2025090409432408000_17.2.122.1","doi-asserted-by":"publisher","DOI":"10.1227\/01.neu.0000303205.15489.23"},{"key":"2025090409432408000_17.2.122.2","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.2009.185884"},{"key":"2025090409432408000_17.2.122.3","unstructured":"Kahle W , Frotscher M . 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