{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T18:49:18Z","timestamp":1792176558470,"version":"4.4.0"},"reference-count":4,"publisher":"BMJ","issue":"5","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["Pract Neurol"],"accepted":{"date-parts":[[2018,1,31]]},"published-print":{"date-parts":[[2018,10]]},"abstract":"<jats:p>Ocular neuromyotonia is a rare, albeit treatable, ocular motor disorder, characterised by recurrent brief episodes of diplopia due to tonic extraocular muscle contraction. Ephaptic transmission in a chronically damaged ocular motor nerve is the possible underlying mechanism. It usually improves with carbamazepine. A 53-year-old woman presented with a 4-month history of recurrent episodes of binocular vertical diplopia (up to 40\/day), either spontaneously or after sustained downward gaze. Between episodes she had a mild left fourth nerve palsy. Sustained downward gaze consistently triggered downward left eye tonic deviation, lasting around 1\u2009min. MR scan of the brain was normal. She improved on starting carbamazepine but developed a rash that necessitated stopping the drug. Switching to lacosamide controlled her symptoms.<\/jats:p>","DOI":"10.1136\/practneurol-2017-001866","type":"journal-article","created":{"date-parts":[[2018,2,21]],"date-time":"2018-02-21T20:45:22Z","timestamp":1519245922000},"page":"389-390","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":21,"title":["Ocular neuromyotonia"],"prefix":"10.1136","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6878-8568","authenticated-orcid":false,"given":"Ricardo","family":"Soares-dos-Reis","sequence":"first","affiliation":[{"name":"Neurology Department, S\u00e3o Jo\u00e3o Hospital Centre, Porto, Portugal"},{"name":"Faculty of Medicine, Porto University, Porto, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana In\u00eas","family":"Martins","sequence":"additional","affiliation":[{"name":"Neurology Department, Coimbra University Hospital Centre, Coimbra, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana","family":"Br\u00e1s","sequence":"additional","affiliation":[{"name":"Neurology Department, Coimbra University Hospital Centre, Coimbra, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anabela","family":"Matos","sequence":"additional","affiliation":[{"name":"Neurology Department, Coimbra University Hospital Centre, Coimbra, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Concei\u00e7\u00e3o","family":"Bento","sequence":"additional","affiliation":[{"name":"Neurology Department, Coimbra University Hospital Centre, Coimbra, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jo\u00e3o","family":"Lemos","sequence":"additional","affiliation":[{"name":"Neurology Department, Coimbra University Hospital Centre, Coimbra, Portugal"},{"name":"Faculty of Medicine, Coimbra University, Coimbra, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2018,2,21]]},"reference":[{"key":"2025090411395334000_18.5.389.1","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/B978-0-444-52903-9.00017-0","article-title":"Infranuclear ocular motor disorders","volume":"102","author":"Lueck","year":"2011","journal-title":"Handb Clin Neurol"},{"key":"2025090411395334000_18.5.389.2","doi-asserted-by":"publisher","DOI":"10.3109\/09273972.2013.787635"},{"key":"2025090411395334000_18.5.389.3","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1007\/s11940-016-0417-2","article-title":"Therapy of Vestibular Paroxysmia, Superior Oblique Myokymia, and Ocular Neuromyotonia","volume":"18","author":"Strupp","year":"2016","journal-title":"Curr Treat Options Neurol"},{"key":"2025090411395334000_18.5.389.4","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/j.eplepsyres.2014.11.021","article-title":"Current understanding of the mechanism of action of the antiepileptic drug lacosamide","volume":"110","author":"Rogawski","year":"2015","journal-title":"Epilepsy Res"}],"container-title":["Practical Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/practneurol-2017-001866","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,4]],"date-time":"2025-09-04T18:40:00Z","timestamp":1757011200000},"score":1,"resource":{"primary":{"URL":"https:\/\/pn.bmj.com\/lookup\/doi\/10.1136\/practneurol-2017-001866"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,2,21]]},"references-count":4,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2018,9,17]]},"published-print":{"date-parts":[[2018,10]]}},"alternative-id":["10.1136\/practneurol-2017-001866"],"URL":"https:\/\/doi.org\/10.1136\/practneurol-2017-001866","relation":{},"ISSN":["1474-7758","1474-7766"],"issn-type":[{"value":"1474-7758","type":"print"},{"value":"1474-7766","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,2,21]]}}}