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This article discusses the utility and limitations of CSF lactate, highlighting specific clinical situations where it can help in the diagnosis of CNS infections and unexplained encephalopathy.<\/jats:p>","DOI":"10.1136\/practneurol-2019-002191","type":"journal-article","created":{"date-parts":[[2020,5,13]],"date-time":"2020-05-13T18:02:25Z","timestamp":1589392945000},"page":"320-323","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":37,"title":["CSF lactate"],"prefix":"10.1136","volume":"20","author":[{"given":"Aravindhan","family":"Baheerathan","sequence":"first","affiliation":[{"name":"Department of Neurology, Charing Cross Hospital, London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6123-4551","authenticated-orcid":false,"given":"Robert DS","family":"Pitceathly","sequence":"additional","affiliation":[{"name":"Department of Neuromuscular Diseases, UCL Queen Square Institute of Neurology and The National Hospital for Neurology and Neurosurgery, London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carmel","family":"Curtis","sequence":"additional","affiliation":[{"name":"Department of Microbiology, University College Hospital London and the National Hospital for Neurology and Neurosurgery, London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicholas WS","family":"Davies","sequence":"additional","affiliation":[{"name":"Department of Neurology, Charing Cross Hospital, London, UK"},{"name":"Department of Neurology, Chelsea and Westminster Hospital, London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2020,5,13]]},"reference":[{"key":"2025090409480192000_20.4.320.1","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1967.00470230044005"},{"key":"2025090409480192000_20.4.320.2","doi-asserted-by":"publisher","DOI":"10.1136\/adc.2005.075317"},{"key":"2025090409480192000_20.4.320.3","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1080\/23744235.2018.1441539","article-title":"Cerebrospinal fluid lactate as a marker to differentiate between community-acquired acute bacterial meningitis and aseptic meningitis\/encephalitis in adults: a Danish prospective observational cohort study","volume":"50","author":"Buch","year":"2018","journal-title":"Infect Dis (Lond)"},{"key":"2025090409480192000_20.4.320.4","doi-asserted-by":"crossref","unstructured":"Huy NT , Thao NTH , Diep DTN , et al. 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