{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T17:52:10Z","timestamp":1757613130553,"version":"3.44.0"},"reference-count":11,"publisher":"BMJ","issue":"3","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["Pract Neurol"],"accepted":{"date-parts":[[2021,11,15]]},"published-print":{"date-parts":[[2022,6]]},"abstract":"<jats:p>Cerebral amyloid angiopathy with related inflammation (CAA-RI) is an uncommon inflammatory subtype of CAA, with a variety of presentations that can mimic other focal and diffuse neurological disorders. We present a 63-year-old man with recurrent stereotyped focal neurological symptoms, who was initially diagnosed as capsular warning syndrome and treated with antithrombotic therapy. Atypical imaging led to further investigation including a cerebral biopsy, which confirmed CAA-RI; he improved clinically and radiologically with immunosuppression. This case highlights how CAA-RI is often under-recognised and that patients risk receiving inappropriate anticoagulation and delay in starting immunosuppression.<\/jats:p>","DOI":"10.1136\/practneurol-2021-003223","type":"journal-article","created":{"date-parts":[[2021,12,16]],"date-time":"2021-12-16T13:21:35Z","timestamp":1639660895000},"page":"216-219","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":1,"title":["Cerebral amyloid angiopathy with related inflammation masquerading as crescendo transient ischaemic attacks"],"prefix":"10.1136","volume":"22","author":[{"given":"Duncan","family":"Maddox","sequence":"first","affiliation":[{"name":"Neurology, Townsville Hospital and Health Service, Townsville, Queensland, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kayla","family":"Ward","sequence":"additional","affiliation":[{"name":"Neurology, Townsville Hospital and Health Service, Townsville, Queensland, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Robertson","sequence":"additional","affiliation":[{"name":"Neuropathology, Pathology Queensland, Herston, Queensland, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mike","family":"Boggild","sequence":"additional","affiliation":[{"name":"Neurology, Townsville Hospital and Health Service, Townsville, Queensland, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2021,12,16]]},"reference":[{"key":"2025090410385414000_22.3.216.1","doi-asserted-by":"crossref","DOI":"10.1016\/j.jns.2021.117425","article-title":"Cerebral amyloid angiopathy and related inflammatory disorders","volume":"424","author":"Chwalisz","year":"2021","journal-title":"J Neurol Sci"},{"key":"2025090410385414000_22.3.216.2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(12)61333-6"},{"key":"2025090410385414000_22.3.216.3","doi-asserted-by":"publisher","DOI":"10.1212\/CPJ.0000000000000579"},{"key":"2025090410385414000_22.3.216.4","doi-asserted-by":"publisher","DOI":"10.7861\/clinmedicine.14-3-255"},{"key":"2025090410385414000_22.3.216.5","doi-asserted-by":"crossref","first-page":"1261","DOI":"10.1001\/jamaneurol.2020.1782","article-title":"Association between immunosuppressive treatment and outcomes of cerebral amyloid angiopathy-related inflammation","volume":"77","author":"Regenhardt","year":"2020","journal-title":"JAMA Neurol"},{"key":"2025090410385414000_22.3.216.6","doi-asserted-by":"crossref","DOI":"10.1007\/s11910-015-0572-y","article-title":"The Inflammatory Form of Cerebral Amyloid Angiopathy or \"Cerebral Amyloid Angiopathy-Related Inflammation\" (CAARI)","volume":"15","author":"Kirshner","year":"2015","journal-title":"Curr Neurol Neurosci Rep"},{"key":"2025090410385414000_22.3.216.7","doi-asserted-by":"crossref","first-page":"205","DOI":"10.5114\/fn.2019.86297","article-title":"Cerebral amyloid angiopathy-related inflammation (CAARI): case report","volume":"57","author":"Makarewicz","year":"2019","journal-title":"Folia Neuropathol"},{"key":"2025090410385414000_22.3.216.8","doi-asserted-by":"publisher","DOI":"10.1159\/000098060"},{"key":"2025090410385414000_22.3.216.9","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.2009.204180"},{"key":"2025090410385414000_22.3.216.10","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1001\/jamaneurol.2015.4078","article-title":"Validation of clinicoradiological criteria for the diagnosis of cerebral amyloid angiopathy-related inflammation","volume":"73","author":"Auriel","year":"2016","journal-title":"JAMA Neurol"},{"key":"2025090410385414000_22.3.216.11","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000003613"}],"container-title":["Practical Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/practneurol-2021-003223","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,4]],"date-time":"2025-09-04T17:39:03Z","timestamp":1757007543000},"score":1,"resource":{"primary":{"URL":"https:\/\/pn.bmj.com\/lookup\/doi\/10.1136\/practneurol-2021-003223"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,12,16]]},"references-count":11,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2022,5,17]]},"published-print":{"date-parts":[[2022,6]]}},"alternative-id":["10.1136\/practneurol-2021-003223"],"URL":"https:\/\/doi.org\/10.1136\/practneurol-2021-003223","relation":{},"ISSN":["1474-7758","1474-7766"],"issn-type":[{"type":"print","value":"1474-7758"},{"type":"electronic","value":"1474-7766"}],"subject":[],"published":{"date-parts":[[2021,12,16]]}}}