{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T19:44:25Z","timestamp":1760211865249,"version":"build-2065373602"},"reference-count":32,"publisher":"BMJ","issue":"12","funder":[{"name":"US Army Medical and Material Command and conducted through the Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc.","award":["Cooperative Agreement #W81XWH-11-2-0201"],"award-info":[{"award-number":["Cooperative Agreement #W81XWH-11-2-0201"]}]}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["Reg Anesth Pain Med"],"accepted":{"date-parts":[[2019,5,29]]},"published-print":{"date-parts":[[2019,12]]},"abstract":"<jats:sec>\n                  <jats:title>Background\/Objective<\/jats:title>\n                  <jats:p>The role of caregiver psychosocial characteristics and their relation to postsurgical caregiving capability remains unclear. The objective of this study was to explore caregiver psychosocial variables following surgery of patients undergoing total joint arthroplasty and spine surgery.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>A prospective observational study was conducted where questionnaires were administered to caregivers preoperatively and 1\u2009week\/2\u2009weeks\/1\u2009month postoperatively. Measures included demographics, caregiver activities and National Institutes of Health Patient Reported Outcomes Measurement Information System (NIH PROMIS) item banks. Bivariate analysis assessed differences between participants reporting baseline pain and those reporting no baseline pain. Generalized estimating equation models examined PROMIS T-scores across time.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>190 caregivers were enrolled and completed surveys. 18% of caregivers reported experiencing a painful condition where they experienced pain during most days of the week. Across all time points, the majority of caregivers reported no worse than mild impairment across PROMIS scores. Compared with baseline, caregivers reported lower PROMIS satisfaction with social roles across all postoperative time points (p&lt;0.001) and higher depression and fatigue at postoperative day 7 (p=0.002) and 14 (p=0.006). PROMIS sleep disturbance was only higher at day 7 (p=0.01). Caregivers reporting a baseline pain condition reported PROMIS scores indicative of higher anxiety (p=0.02), depression (p=0.003), sleep disturbances (p&lt;0.001) and fatigue (p&lt;0.001) and lower levels of satisfaction with social roles (p=0.002) compared with those caregivers without baseline pain.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>While there were transient worsening in PROMIS scores, it is unclear whether these were clinically meaningful. Postsurgical caregivers reporting baseline pain were characterized by worse functioning across all PROMIS scales.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1136\/rapm-2019-100380","type":"journal-article","created":{"date-parts":[[2019,11,6]],"date-time":"2019-11-06T04:34:11Z","timestamp":1573014851000},"page":"1084-1090","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":1,"title":["Caregiver Patient Reported Outcomes Measurement Information System (PROMIS) profiles in patients undergoing total joint arthroplasty and spine surgery: a prospective observational cohort study"],"prefix":"10.1136","volume":"44","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9051-2645","authenticated-orcid":false,"given":"Michael L","family":"Kent","sequence":"first","affiliation":[{"name":"Anesthesiology, Duke University Hospital, Durham, North Carolina, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8119-6962","authenticated-orcid":false,"given":"Kalyn","family":"Jannace","sequence":"additional","affiliation":[{"name":"Defense and Veterans Center for Integrative Pain Management, Rockville, Maryland, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Krista B","family":"Highland","sequence":"additional","affiliation":[{"name":"Defense and Veterans Center for Integrative Pain Management, Rockville, Maryland, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria","family":"Dimarzio","sequence":"additional","affiliation":[{"name":"Defense and Veterans Center for Integrative Pain Management, Rockville, Maryland, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julie","family":"Tran","sequence":"additional","affiliation":[{"name":"Defense and Veterans Center for Integrative Pain Management, Rockville, Maryland, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sara","family":"Gonzalez","sequence":"additional","affiliation":[{"name":"Defense and Veterans Center for Integrative Pain Management, Rockville, Maryland, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chester C","family":"Buckenmaier","sequence":"additional","affiliation":[{"name":"Defense and Veterans Center for Integrative Pain Management, Rockville, Maryland, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2019,11,5]]},"reference":[{"key":"2025101112010571000_44.12.1084.1","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1016\/j.jpainsymman.2015.04.005","article-title":"Comparative analysis of informal caregiver burden in advanced cancer, dementia, and acquired brain injury","volume":"50","author":"Harding","year":"2015","journal-title":"J Pain Symptom Manage"},{"key":"2025101112010571000_44.12.1084.2","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.apnr.2017.09.011","article-title":"Changes over time in caregiving demand and difficulty in spousal caregivers of coronary artery bypass graft surgery patients","volume":"39","author":"Yates","year":"2018","journal-title":"Applied Nursing Research"},{"key":"2025101112010571000_44.12.1084.3","doi-asserted-by":"crossref","unstructured":"Ariza-Vega P , Ortiz-Pi\u00f1a M , Kristensen MT , et al . 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