{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T02:54:56Z","timestamp":1790477696423,"version":"4.1.0"},"reference-count":25,"publisher":"BMJ","issue":"1","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["Reg Anesth Pain Med"],"accepted":{"date-parts":[[2019,10,29]]},"published-print":{"date-parts":[[2020,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background and objectives<\/jats:title>\n                    <jats:p>The anesthetic characteristics of ultrasound-guided erector spinae plane block (ESPB) remain unclear. We compared the analgesic efficacies of ESPB and thoracic paravertebral block (TPVB) for analgesia after video-assisted thoracic surgery (VATS).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method<\/jats:title>\n                    <jats:p>In this prospective randomized non-inferiority trial, 88 patients undergoing VATS randomly received ESPB or TPVB. All patients received continuous infusion of 0.2% levobupivacaine (8\u2009mL\/hour) after injection of a 20\u2009mL 0.2% levobupivacaine bolus. The primary outcome was median differences between the groups in postoperative numerical rating scale (NRS) scores at rest, 24\u2009hours postoperatively.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Eighty-one patients completed the study. The median difference in NRS scores at rest 24\u2009hours postoperatively was 1 (range 0\u20131), demonstrating the non-inferiority of ESPB to TPVB. NRS scores at rest were significantly lower in the TPVB group at 1, 2 and 24\u2009hours postoperatively (p=0.02, 0.01 and 0.006, respectively). NRS scores on movement were similar. More dermatomes in parasternal regions were anaesthetized in the TPVB group (p&lt;0.0001). Total plasma levobupivacaine concentrations were significantly lower in the ESPB group within 20\u2009hours postoperatively (p=0.036).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The analgesic effect of ESPB after VATS was non-inferior to that of TPVB 24\u2009hours postoperatively.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Trial registration number<\/jats:title>\n                    <jats:p>UMIN000030658.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1136\/rapm-2019-100827","type":"journal-article","created":{"date-parts":[[2019,11,8]],"date-time":"2019-11-08T18:15:16Z","timestamp":1573236916000},"page":"10-15","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":117,"title":["Comparison of ultrasound-guided erector spinae plane block and thoracic paravertebral block for postoperative analgesia after video-assisted thoracic surgery: a randomized controlled non-inferiority clinical trial"],"prefix":"10.1136","volume":"45","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2581-3334","authenticated-orcid":false,"given":"Yasuko","family":"Taketa","sequence":"first","affiliation":[{"name":"Department of Anesthesiology and Critical Care, Ehime Prefectural Central Hospital, Matsuyama, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yumi","family":"Irisawa","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Critical Care, Ehime Prefectural Central Hospital, Matsuyama, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Taro","family":"Fujitani","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Critical Care, Ehime Prefectural Central Hospital, Matsuyama, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2019,11,8]]},"reference":[{"key":"2025101110341810000_45.1.10.1","doi-asserted-by":"crossref","first-page":"1185","DOI":"10.1111\/anae.14348","article-title":"Paravertebral by proxy \u2013 time to redefine the paravertebral block","volume":"73","author":"Costache","year":"2018","journal-title":"Anaesthesia"},{"key":"2025101110341810000_45.1.10.2","doi-asserted-by":"publisher","DOI":"10.1097\/AAP.0000000000000451"},{"key":"2025101110341810000_45.1.10.3","doi-asserted-by":"publisher","DOI":"10.1097\/AAP.0000000000000798"},{"key":"2025101110341810000_45.1.10.4","doi-asserted-by":"crossref","first-page":"1244","DOI":"10.1111\/anae.14408","article-title":"Comparison of injectate spread and nerve involvement between retrolaminar and erector spinae plane blocks in the thoracic region: a cadaveric 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