{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,29]],"date-time":"2026-08-29T04:25:32Z","timestamp":1787977532878,"version":"build-2784847793"},"reference-count":18,"publisher":"BMJ","issue":"1","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["Reg Anesth Pain Med"],"accepted":{"date-parts":[[2019,10,18]]},"published-print":{"date-parts":[[2020,1]]},"abstract":"<jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Erector spinae plane block (ESPB) is a novel regional anesthesia technique that is gaining popularity for postoperative pain management. This randomized controlled trial evaluated the effect of ESPB on quality of recovery (QoR) in patients undergoing modified radical mastectomy.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>Eighty-two female patients undergoing modified radical mastectomy were included. Patients were randomly assigned to receive preoperative ultrasound-guided ESPB with either 0.5% ropivacaine or saline. The primary outcome was QoR, assessed 24\u2009hours postoperatively using the 15-item QoR questionnaire (QoR-15). Secondary outcomes included postoperative pain scores, postoperative cumulative opioid consumption, postanesthesia care unit (PACU) discharge time, postoperative nausea or vomiting and dizziness.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Global QoR-15 scores 24\u2009hours postoperatively were significantly higher (indicating better quality) in the ESPB group (median 120, IQR 118\u2013124) compared with the control group (median 110, IQR 108.3\u2013112.8), with a median difference of 10 (95% CI 9 to 12, p&lt;0.001). Compared with the control group, ESPB with ropivacaine reduced pain scores up to 8\u2009hours after surgery, as well as reduced postoperative cumulative opioid consumption and PACU discharge time.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>A single preoperative injection of ESPB with ropivacaine may improve QoR postoperatively and acute postoperative analgesia in patients undergoing a modified radical mastectomy.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Trial registration number<\/jats:title>\n                  <jats:p>ChiCTR-1800019599.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1136\/rapm-2019-100983","type":"journal-article","created":{"date-parts":[[2019,11,2]],"date-time":"2019-11-02T10:04:14Z","timestamp":1572689054000},"page":"5-9","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":63,"title":["Efficacy of ultrasound-guided erector spinae plane block on postoperative quality of recovery and analgesia after modified radical mastectomy: randomized controlled trial"],"prefix":"10.1136","volume":"45","author":[{"given":"Yusheng","family":"Yao","sequence":"first","affiliation":[{"name":"Shengli Clinical Medical College, Fujian Medical University, Fuzhou, China"},{"name":"Anesthesiology, Fujian Provincial Hospital, Fuzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hao","family":"Li","sequence":"additional","affiliation":[{"name":"Anesthesiology, Fujian Provincial Hospital, Fuzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiaolan","family":"He","sequence":"additional","affiliation":[{"name":"Anesthesiology, Fujian Medical University, Fuzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tingting","family":"Chen","sequence":"additional","affiliation":[{"name":"Anesthesiology, Fujian University of Traditional Chinese Medicine, Fuzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yihang","family":"Wang","sequence":"additional","affiliation":[{"name":"Anesthesiology, Fujian Medical University, Fuzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6483-6697","authenticated-orcid":false,"given":"Xiaochun","family":"Zheng","sequence":"additional","affiliation":[{"name":"Shengli Clinical Medical College, Fujian Medical University, Fuzhou, China"},{"name":"Anesthesiology, Fujian Provincial Hospital, Fuzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2019,11,2]]},"reference":[{"key":"2025101110205843000_45.1.5.1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21492"},{"key":"2025101110205843000_45.1.5.2","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1002\/jso.24814","article-title":"Enhanced recovery after surgery: pain management","volume":"116","author":"Nimmo","year":"2017","journal-title":"J Surg Oncol"},{"key":"2025101110205843000_45.1.5.3","doi-asserted-by":"crossref","first-page":"e115","DOI":"10.1016\/j.anclin.2017.01.018","article-title":"Essential elements of multimodal analgesia in enhanced recovery after surgery (ERAS) guidelines","volume":"35","author":"Beverly","year":"2017","journal-title":"Anesthesiol Clin"},{"key":"2025101110205843000_45.1.5.4","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1016\/j.ijnurstu.2019.06.010","article-title":"An integrative review of multimodal pain management on patient recovery after total hip and knee arthroplasty","volume":"98","author":"Zhao","year":"2019","journal-title":"Int J Nurs Stud"},{"key":"2025101110205843000_45.1.5.5","doi-asserted-by":"crossref","first-page":"596","DOI":"10.1097\/EJA.0000000000000673","article-title":"Thoracic paravertebral block for postoperative pain management after renal surgery: a randomised controlled trial","volume":"34","author":"Copik","year":"2017","journal-title":"Eur J Anaesthesiol"},{"key":"2025101110205843000_45.1.5.6","doi-asserted-by":"publisher","DOI":"10.1097\/AAP.0000000000000451"},{"key":"2025101110205843000_45.1.5.7","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.jclinane.2018.06.019","article-title":"Evaluation of ultrasound-guided erector spinae plane block for postoperative analgesia in laparoscopic cholecystectomy: a prospective, randomized, controlled clinical trial","volume":"49","author":"Tulgar","year":"2018","journal-title":"J Clin Anesth"},{"key":"2025101110205843000_45.1.5.8","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1053\/j.jvca.2018.05.050","article-title":"Bilateral erector spinae plane block for acute post-surgical pain in adult cardiac surgical patients: a randomized controlled trial","volume":"33","author":"Krishna","year":"2019","journal-title":"J Cardiothorac Vasc Anesth"},{"key":"2025101110205843000_45.1.5.9","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/j.jclinane.2018.06.033","article-title":"Ultrasound guided erector spinae plane block reduces postoperative opioid consumption following breast surgery: a randomized controlled study","volume":"50","author":"G\u00fcrkan","year":"2018","journal-title":"J Clin Anesth"},{"key":"2025101110205843000_45.1.5.10","doi-asserted-by":"crossref","DOI":"10.1007\/s11916-019-0812-y","article-title":"Expanding role of the erector spinae plane block for postoperative and chronic pain management","volume":"23","author":"Urits","year":"2019","journal-title":"Curr Pain Headache Rep"},{"key":"2025101110205843000_45.1.5.11","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1016\/j.jclinane.2019.06.036","article-title":"Erector spinae plane block and thoracic paravertebral block for breast surgery compared to IV-morphine: a randomized controlled trial","volume":"59","author":"G\u00fcrkan","year":"2020","journal-title":"J Clin Anesth"},{"key":"2025101110205843000_45.1.5.12","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1007\/s40271-015-0148-6","article-title":"Validation of the Chinese version of the quality of Recovery-15 score and its comparison with the post-operative quality recovery scale","volume":"9","author":"Bu","year":"2016","journal-title":"Patient"},{"key":"2025101110205843000_45.1.5.13","doi-asserted-by":"publisher","DOI":"10.1097\/ALN.0b013e318289b84b"},{"key":"2025101110205843000_45.1.5.14","doi-asserted-by":"publisher","DOI":"10.1016\/0952-8180(94)00001-K"},{"key":"2025101110205843000_45.1.5.15","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1097\/ALN.0000000000001158","article-title":"Minimal clinically important difference for three quality of recovery scales","volume":"125","author":"Myles","year":"2016","journal-title":"Anesthesiology"},{"key":"2025101110205843000_45.1.5.16","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1016\/j.bpa.2018.07.002","article-title":"Defining quality of recovery - What is important to patients?","volume":"32","author":"Borrell-Vega","year":"2018","journal-title":"Best Pract Res Clin Anaesthesiol"},{"key":"2025101110205843000_45.1.5.17","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1097\/ACO.0000000000000612","article-title":"Measuring quality of recovery in perioperative clinical trials","volume":"31","author":"Myles","year":"2018","journal-title":"Curr Opin Anaesthesiol"},{"key":"2025101110205843000_45.1.5.18","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/aev413"}],"container-title":["Regional Anesthesia &amp; Pain Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/rapm-2019-100983","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T17:21:03Z","timestamp":1760203263000},"score":1,"resource":{"primary":{"URL":"https:\/\/rapm.bmj.com\/lookup\/doi\/10.1136\/rapm-2019-100983"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,11,2]]},"references-count":18,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2019,12,12]]},"published-print":{"date-parts":[[2020,1]]}},"alternative-id":["10.1136\/rapm-2019-100983"],"URL":"https:\/\/doi.org\/10.1136\/rapm-2019-100983","relation":{},"ISSN":["1098-7339","1532-8651"],"issn-type":[{"value":"1098-7339","type":"print"},{"value":"1532-8651","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,11,2]]}}}