{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T13:42:45Z","timestamp":1792762965641,"version":"4.5.0"},"reference-count":12,"publisher":"BMJ","issue":"10","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["Reg Anesth Pain Med"],"accepted":{"date-parts":[[2021,7,13]]},"published-print":{"date-parts":[[2021,10]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>This randomized trial compared ultrasound-guided pericapsular nerve group block and suprainguinal fascia iliaca block in patients undergoing primary total hip arthroplasty. We selected the postoperative incidence of quadriceps motor block (defined as paresis or paralysis of knee extension) at 6\u2009hours as the primary outcome. We hypothesized that, compared with suprainguinal fascia iliaca block, pericapsular nerve group block would decrease its occurrence from 70% to 20%.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Forty patients undergoing primary total hip arthroplasty under spinal anesthesia were randomly allocated to receive a pericapsular nerve group block (n=20) using 20\u2009mL of adrenalized levobupivacaine 0.50%, or a suprainguinal fascia iliaca block (n=20) using 40\u2009mL of adrenalized levobupivacaine 0.25%. After the performance of the block, a blinded observer recorded pain scores at 3, 6, 12, 18, 24, 36, and 48 hours; cumulative breakthrough morphine consumption at 24 and 48 hours; opioid-related side effects; ability to perform physiotherapy at 24 and 48 hours; as well as length of stay. Furthermore, the blinded observer also carried out sensory assessment (of the anterior, lateral, and medial aspects of the mid-thigh) and motor assessment (knee extension and hip adduction) at 3, 6, and 24 hours.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Compared with suprainguinal fascia iliaca block, pericapsular nerve group block resulted in a lower incidence of quadriceps motor block at 3\u2009hours (45% vs 90%; p&lt;0.001) and 6\u2009hours (25% vs 85%; p&lt;0.001). Furthermore, pericapsular nerve group block also provided better preservation of hip adduction at 3\u2009hours (p=0.023) as well as decreased sensory block of the anterior, lateral, and medial thighs at all measurement intervals (all p\u22640.014). No clinically significant intergroup differences were found in terms of postoperative pain scores, cumulative opioid consumption at 24 and 48 hours, ability to perform physiotherapy, opioid-related side effects, and length of hospital stay.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>For primary total hip arthroplasty, pericapsular nerve group block results in better preservation of motor function than suprainguinal fascia iliaca block. Additional investigation is required to elucidate the optimal local anesthetic volume for motor-sparing pericapsular nerve group block and to compare the latter with alternate motor-sparing strategies such as periarticular local anesthetic infiltration.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Trial registration number<\/jats:title>\n                    <jats:p>\n                      <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"clintrialgov\" xlink:href=\"NCT04402450\">NCT04402450<\/jats:ext-link>\n                      .\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1136\/rapm-2021-102997","type":"journal-article","created":{"date-parts":[[2021,7,20]],"date-time":"2021-07-20T23:25:12Z","timestamp":1626823512000},"page":"874-878","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":185,"title":["Randomized comparison between pericapsular nerve group (PENG) block and suprainguinal fascia iliaca block for total hip arthroplasty"],"prefix":"10.1136","volume":"46","clinical-trial-number":[{"clinical-trial-number":"nct04402450","registry":"10.18810\/clinical-trials-gov"},{"clinical-trial-number":"nct04402450","registry":"10.18810\/clinical-trials-gov"}],"author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6355-1270","authenticated-orcid":false,"given":"Juli\u00e1n","family":"Aliste","sequence":"first","affiliation":[{"name":"Anesthesiology and Perioperative Medicine, University of Chile, Santiago, Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5690-9609","authenticated-orcid":false,"given":"Sebasti\u00e1n","family":"Layera","sequence":"additional","affiliation":[{"name":"Anesthesiology and Perioperative Medicine, University of Chile, Santiago, Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0611-3623","authenticated-orcid":false,"given":"Daniela","family":"Bravo","sequence":"additional","affiliation":[{"name":"Anesthesiology and Perioperative Medicine, University of Chile, Santiago, Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u00c1lvaro","family":"Jara","sequence":"additional","affiliation":[{"name":"Anesthesiology and Perioperative Medicine, University of Chile, Santiago, Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gonzalo","family":"Mu\u00f1oz","sequence":"additional","affiliation":[{"name":"Anesthesiology and Perioperative Medicine, University of Chile, Santiago, Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cristi\u00e1n","family":"Barrientos","sequence":"additional","affiliation":[{"name":"Orthopedic Surgery, University of Chile, Santiago, Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rodrigo","family":"Wulf","sequence":"additional","affiliation":[{"name":"Orthopedic Surgery, University of Chile, Santiago, Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juli\u00e1n","family":"Bra\u00f1ez","sequence":"additional","affiliation":[{"name":"Orthopedic Surgery, University of Chile, Santiago, Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3845-6367","authenticated-orcid":false,"given":"Roderick J","family":"Finlayson","sequence":"additional","affiliation":[{"name":"Pain and Research, The University of British Columbia, Kelowna, British Columbia, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5345-1804","authenticated-orcid":false,"given":"De Q","family":"Tran","sequence":"additional","affiliation":[{"name":"Anesthesiology, McGill University, Montreal, Qu\u00e9bec, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2021,7,20]]},"reference":[{"key":"2026102306300713000_46.10.874.1","doi-asserted-by":"publisher","DOI":"10.1097\/AAP.0000000000000543"},{"key":"2026102306300713000_46.10.874.2","doi-asserted-by":"crossref","DOI":"10.1016\/j.jclinane.2020.109907","article-title":"Lumbar plexus block versus suprainguinal fascia iliaca block for total hip arthroplasty: a single-blinded, randomized trial","volume":"66","author":"Bravo","year":"2020","journal-title":"J Clin Anesth"},{"key":"2026102306300713000_46.10.874.3","doi-asserted-by":"publisher","DOI":"10.5301\/hipint.5000100"},{"key":"2026102306300713000_46.10.874.4","first-page":"112070002097821","article-title":"The pericapsular nerve group block: a step towards outpatient total hip arthroplasty?","author":"Remily","year":"2020","journal-title":"Hip Int"},{"key":"2026102306300713000_46.10.874.5","doi-asserted-by":"publisher","DOI":"10.1097\/AAP.0000000000000707"},{"key":"2026102306300713000_46.10.874.6","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbi.2008.08.010"},{"key":"2026102306300713000_46.10.874.7","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1097\/EJA.0000000000000736","article-title":"Ultrasound with neurostimulation compared with ultrasound guidance alone for lumbar plexus block: a randomised single blinded equivalence trial","volume":"35","author":"Arnuntasupakul","year":"2018","journal-title":"Eur J Anaesthesiol"},{"key":"2026102306300713000_46.10.874.8","doi-asserted-by":"publisher","DOI":"10.1136\/rapm-2020-102315"},{"key":"2026102306300713000_46.10.874.9","doi-asserted-by":"publisher","DOI":"10.1136\/rapm-2018-100354"},{"key":"2026102306300713000_46.10.874.10","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/j.jclinane.2019.07.006","article-title":"Gray zone of pericapsular nerve group (PENG) block","volume":"58","author":"Mistry","year":"2019","journal-title":"J Clin Anesth"},{"key":"2026102306300713000_46.10.874.11","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1053\/j.jvca.2019.10.027","article-title":"Reply to Aydin et al.: a novel indication of Pericapsular nerve group block: surgical anesthesia for vein ligation and stripping","volume":"34","author":"Gir\u00f3n-Arango","year":"2020","journal-title":"J Cardiothorac Vasc Anesth"},{"key":"2026102306300713000_46.10.874.12","doi-asserted-by":"crossref","unstructured":"Pascarella G , Costa F , Del Buono R . Impact of the pericapsular nerve group (PENG) block on postoperative analgesia and functional recovery following total hip arthroplasty: a randomised, observer\u2010masked, controlled trial. Anaesthesia 2021;8.doi:10.1111\/anae.15536","DOI":"10.1111\/anae.15536"}],"container-title":["Regional Anesthesia &amp; Pain Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/rapm-2021-102997","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T13:31:11Z","timestamp":1792762271000},"score":1,"resource":{"primary":{"URL":"https:\/\/rapm.bmj.com\/lookup\/doi\/10.1136\/rapm-2021-102997"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,7,20]]},"references-count":12,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2021,9,20]]},"published-print":{"date-parts":[[2021,10]]}},"alternative-id":["10.1136\/rapm-2021-102997"],"URL":"https:\/\/doi.org\/10.1136\/rapm-2021-102997","relation":{},"ISSN":["1098-7339","1532-8651"],"issn-type":[{"value":"1098-7339","type":"print"},{"value":"1532-8651","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,7,20]]}}}