{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T02:54:32Z","timestamp":1790477672378,"version":"4.1.0"},"reference-count":16,"publisher":"BMJ","issue":"12","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["Reg Anesth Pain Med"],"accepted":{"date-parts":[[2022,9,9]]},"published-print":{"date-parts":[[2022,12]]},"abstract":"<jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Despite advances in minimally invasive thoracic surgery, patients remain at risk of adverse pulmonary events with suboptimal postoperative analgesia. Novel methods of regional analgesia are warranted. Our objective was to prospectively evaluate the impact of ultrasound-guided single-injection erector spinae plane (ESP) block with ropivacaine compared with placebo control on standard of care postoperative recovery in subjects undergoing video-assisted thoracoscopic surgery (VATS) wedge resection.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>This prospective, randomized, placebo-controlled, double-blinded study was conducted at a tertiary thoracic surgical center. Consecutive subjects undergoing VATS wedge resection were randomized to receive a single-injection ESP block with 0.5% ropivacaine or 0.9% saline placebo, in addition to the current standard of care of multimodal analgesia including patient-controlled analgesia and surgical local anesthetic wound infiltration. The primary outcome was difference in 40-point Quality of Recovery (QoR-40) on day 1 postoperatively. The secondary outcomes included opioid consumption, Visual Analog Pain Scale (VAS) score, time spent in the postanesthesia care unit (PACU), and block-related and postoperative complications.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Eighty subjects were enrolled, 40 in each group, with 76 completing follow-up (38 subjects in each group). There was no difference in the median QoR-40 score between groups, 169.5 for the ropivacaine group and 172.5 for the control group (difference 3, p=0.843). No significant differences existed between groups in all secondary outcomes, with the exception of the ropivacaine group having lower VAS pain scores measured at 1\u2009hour postoperatively and a shorter duration of stay in the PACU of 117\u2009min.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>Following VATS wedge resection, the addition of an ESP block with ropivacaine to standard multimodal analgesia is unlikely to add meaningful clinical value.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Trial registration number<\/jats:title>\n                  <jats:p>\n                     <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"clintrialgov\" specific-use=\"clinicaltrial results\" xlink:href=\"NCT03419117\">NCT03419117<\/jats:ext-link>.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1136\/rapm-2022-103602","type":"journal-article","created":{"date-parts":[[2022,9,23]],"date-time":"2022-09-23T11:23:58Z","timestamp":1663932238000},"page":"749-754","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":20,"title":["Efficacy of ultrasound-guided single-injection erector spinae plane block for thoracoscopic wedge resection: a prospective randomized control trial"],"prefix":"10.1136","volume":"47","clinical-trial-number":[{"clinical-trial-number":"nct03419117","registry":"10.18810\/clinical-trials-gov","type":"results"}],"author":[{"given":"Beau","family":"Klaibert","sequence":"first","affiliation":[{"name":"Department of Anesthesiology and Perioperative Care, Vancouver General Hospital, Vancouver, British Columbia, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jens","family":"Lohser","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Perioperative Care, Vancouver General Hospital, Vancouver, British Columbia, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raymond","family":"Tang","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Perioperative Care, Vancouver General Hospital, Vancouver, British Columbia, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Jew","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Perioperative Care, Vancouver General Hospital, Vancouver, British Columbia, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"McGuire","sequence":"additional","affiliation":[{"name":"Department of Surgery, Division of Thoracic Surgery, Vancouver General Hospital, Vancouver, British Columbia, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jason","family":"Wilson","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Perioperative Care, Vancouver General Hospital, Vancouver, British Columbia, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2022,9,23]]},"reference":[{"key":"2025101113200118000_47.12.749.1","doi-asserted-by":"publisher","DOI":"10.1097\/AAP.0000000000000451"},{"key":"2025101113200118000_47.12.749.2","doi-asserted-by":"publisher","DOI":"10.1007\/s12630-020-01875-2"},{"key":"2025101113200118000_47.12.749.3","doi-asserted-by":"crossref","DOI":"10.1016\/j.jclinane.2022.110763","article-title":"Retraction notice to \u201cPneumothorax after the erector spinae plane block\u201d [J. Clin. Anesth. 48(2018)12]","volume":"79","author":"Ueshima","year":"2022","journal-title":"J Clin Anesth"},{"key":"2025101113200118000_47.12.749.4","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1016\/j.sjpain.2017.08.013","article-title":"Erector spinae plane (ESP) block in the management of post thoracotomy pain syndrome: a case series","volume":"17","author":"Forero","year":"2017","journal-title":"Scand J Pain"},{"key":"2025101113200118000_47.12.749.5","doi-asserted-by":"crossref","first-page":"1391","DOI":"10.1016\/j.ajem.2017.12.060","article-title":"Successful emergency pain control for posterior rib fractures with ultrasound-guided erector spinae plane block","volume":"36","author":"Luftig","year":"2018","journal-title":"Am J Emerg Med"},{"key":"2025101113200118000_47.12.749.6","doi-asserted-by":"crossref","first-page":"e5","DOI":"10.1053\/j.jvca.2018.06.026","article-title":"Erector spinae plane block for postoperative rescue analgesia in thoracoscopic surgery","volume":"32","author":"Wilson","year":"2018","journal-title":"J Cardiothorac Vasc Anesth"},{"key":"2025101113200118000_47.12.749.7","doi-asserted-by":"crossref","DOI":"10.1016\/j.jclinane.2020.109783","article-title":"Impact of ultrasound-guided erector spinae plane block on postoperative quality of recovery in video-assisted thoracic surgery: a prospective, randomized, controlled trial","volume":"63","author":"Yao","year":"2020","journal-title":"J Clin Anesth"},{"key":"2025101113200118000_47.12.749.8","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1053\/j.jvca.2019.04.026","article-title":"Efficacy of an ultrasound-guided erector spinae plane block for postoperative analgesia management after video-assisted thoracic surgery: a prospective randomized study","volume":"34","author":"Ciftci","year":"2020","journal-title":"J Cardiothorac Vasc Anesth"},{"key":"2025101113200118000_47.12.749.9","doi-asserted-by":"crossref","first-page":"1371","DOI":"10.1007\/s12630-020-01759-5","article-title":"A pilot randomized-controlled trial evaluating the erector spinae plane block in thoracic and breast surgery","volume":"67","author":"Uda","year":"2020","journal-title":"Can J Anaesth"},{"key":"2025101113200118000_47.12.749.10","doi-asserted-by":"publisher","DOI":"10.1136\/rapm-2019-100827"},{"key":"2025101113200118000_47.12.749.11","doi-asserted-by":"crossref","first-page":"2920","DOI":"10.1053\/j.jvca.2020.11.034","article-title":"Thoracic paravertebral block achieves better pain control than erector spinae plane block and intercostal nerve block in thoracoscopic surgery: a randomized study","volume":"35","author":"Turhan","year":"2021","journal-title":"J Cardiothorac Vasc Anesth"},{"key":"2025101113200118000_47.12.749.12","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1016\/j.jclinane.2019.07.002","article-title":"The effect of ultrasound-guided intercostal nerve block, single-injection erector spinae plane block and multiple-injection paravertebral block on postoperative analgesia in thoracoscopic surgery: a randomized, double-blinded, clinical trial","volume":"59","author":"Chen","year":"2020","journal-title":"J Clin Anesth"},{"key":"2025101113200118000_47.12.749.13","unstructured":"Faculty of Pain Medicine, Australian and New Zealand College of Anaesthetists . Appendix 2: opioid dose equivalence calculation table, PMO1: recommendations regarding the use of opioid analgesics in patients with chronic non-cancer pain. Melbourne: Faculty of Pain Medicine, Australian and New Zealand College of Anaesthetists, 2021. https:\/\/www.anzca.edu.au\/safety-advocacy\/standards-of-practice\/policies,-statements,-and-guidelines"},{"key":"2025101113200118000_47.12.749.14","doi-asserted-by":"crossref","first-page":"1353","DOI":"10.1213\/ANE.0000000000002779","article-title":"Efficacy of ultrasound-guided serratus plane block on postoperative quality of recovery and analgesia after video-assisted thoracic surgery: a randomized, triple-blind, placebo-controlled study","volume":"126","author":"Kim","year":"2018","journal-title":"Anesth Analg"},{"key":"2025101113200118000_47.12.749.15","doi-asserted-by":"publisher","DOI":"10.1097\/ALN.0000000000001158"},{"key":"2025101113200118000_47.12.749.16","doi-asserted-by":"crossref","DOI":"10.12688\/f1000research.16857.1","article-title":"Continuous surgical multi-level extrapleural block for video-assisted thoracoscopic surgery: a retrospective study assessing its efficacy as pain relief following lobectomy and wedge resection","volume":"7","author":"Larsson","year":"2018","journal-title":"F1000Res"}],"container-title":["Regional Anesthesia &amp; Pain Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/rapm-2022-103602","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T20:20:12Z","timestamp":1760214012000},"score":1,"resource":{"primary":{"URL":"https:\/\/rapm.bmj.com\/lookup\/doi\/10.1136\/rapm-2022-103602"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,9,23]]},"references-count":16,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2022,10,25]]},"published-print":{"date-parts":[[2022,12]]}},"alternative-id":["10.1136\/rapm-2022-103602"],"URL":"https:\/\/doi.org\/10.1136\/rapm-2022-103602","relation":{},"ISSN":["1098-7339","1532-8651"],"issn-type":[{"value":"1098-7339","type":"print"},{"value":"1532-8651","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,9,23]]}}}