{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T01:06:01Z","timestamp":1793235961406,"version":"4.5.0"},"reference-count":18,"publisher":"BMJ","issue":"11","funder":[{"name":"Singapore General Hospital Research Grant","award":["SRG-OPN-01-2021"],"award-info":[{"award-number":["SRG-OPN-01-2021"]}]}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["Reg Anesth Pain Med"],"accepted":{"date-parts":[[2023,3,15]]},"published-print":{"date-parts":[[2023,11]]},"abstract":"<jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>The pericapsular nerve group block (PENG) is a novel technique that blocks the articular branches of the hip joint. This study aimed to compare its effectiveness to a sham block in elderly patients with hip fractures.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Method<\/jats:title>\n                  <jats:p>A randomized double-blind controlled trial was conducted in elderly patients with intertrochanteric and neck of femur fractures. Patients were randomized to receive either PENG block or a sham block. Postblock, systemic analgesia was titrated using a standardized protocol of acetaminophen, oral morphine or patient-controlled analgesia. The primary outcome was the dynamic pain score (Numerical Rating Scale 0\u201310) at 30\u2009min postblock. Secondary outcomes included pain scores at multiple other time points and 24-hour opioid consumption.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>60\u2009patients were randomized and 57 completed the trial (PENG n=28, control n=29). Patients in PENG group had significantly lower dynamic pain scores at 30\u2009min compared with control group (median (IQR) 3 (0.5\u20135) vs 5 (3\u201310), p&lt;0.01). For the secondary outcomes, dynamic pain scores were lower in PENG group at 1\u2009hour (median (IQR) 2 (1\u20133.25) vs 5 (3\u20138), p&lt;0.01) and 3\u2009hours postblock (median (IQR) 2 (0\u20135) vs 5 (2\u20138), p&lt;0.05). Patients in PENG group had lower 24-hour opioid consumption (median (IQR) oral morphine equivalent dose 10 (0\u201315) vs 15 (10\u201330) mg, p&lt;0.05).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>PENG block provided effective analgesia for acute traumatic pain following hip fracture. Further studies are required to validate the superiority of PENG blocks over other regional techniques.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Trial registration number<\/jats:title>\n                  <jats:p>\n                     <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"clintrialgov\" xlink:href=\"NCT04996979\">NCT04996979<\/jats:ext-link>.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1136\/rapm-2022-104117","type":"journal-article","created":{"date-parts":[[2023,4,13]],"date-time":"2023-04-13T14:15:34Z","timestamp":1681395334000},"page":"535-539","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":44,"title":["Pericapsular nerve group (PENG) block for early pain management of elderly patients with hip fracture: a single-center double-blind randomized controlled trial"],"prefix":"10.1136","volume":"48","clinical-trial-number":[{"clinical-trial-number":"nct04996979","registry":"10.18810\/clinical-trials-gov"},{"clinical-trial-number":"nct04996979","registry":"10.18810\/clinical-trials-gov"}],"author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1987-0068","authenticated-orcid":false,"given":"XUFENG","family":"LIN","sequence":"first","affiliation":[{"name":"Division of Anaesthesiology and Perioperative Medicine, Singapore General Hospital, Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7807-9263","authenticated-orcid":false,"given":"Christopher Weiyang","family":"Liu","sequence":"additional","affiliation":[{"name":"Pain Medicine, Singapore General Hospital, Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qing Yuan","family":"Goh","sequence":"additional","affiliation":[{"name":"Division of Anaesthesiology and Perioperative Medicine, Singapore General Hospital, Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eileen Yilin","family":"Sim","sequence":"additional","affiliation":[{"name":"The Anaesthetic Clinic @ Alvernia, Mount Alvernia Hospital, Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steffi Kang Ting","family":"Chan","sequence":"additional","affiliation":[{"name":"Division of Anaesthesiology and Perioperative Medicine, Singapore General Hospital, Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhen Wei","family":"Lim","sequence":"additional","affiliation":[{"name":"Division of Anaesthesiology and Perioperative Medicine, Singapore General Hospital, Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diana Xin Hui","family":"Chan","sequence":"additional","affiliation":[{"name":"Division of Anaesthesiology and Perioperative Medicine, Singapore General Hospital, Singapore"},{"name":"Pain Medicine, Singapore General Hospital, Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2023,4,13]]},"reference":[{"key":"2025101110241670000_48.11.535.1","doi-asserted-by":"crossref","DOI":"10.1136\/bmjopen-2020-047258","article-title":"Global epidemiology of hip fractures: a study protocol using a common analytical platform among multiple countries","volume":"11","author":"Sing","year":"2021","journal-title":"BMJ Open"},{"key":"2025101110241670000_48.11.535.2","doi-asserted-by":"crossref","first-page":"100825","DOI":"10.1016\/j.ienj.2019.100825","article-title":"Evaluation of the intensity and management of pain before arrival in hospital among patients with suspected hip fractures","volume":"49","author":"Wennberg","year":"2020","journal-title":"Int Emerg Nurs"},{"key":"2025101110241670000_48.11.535.3","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s40266-016-0427-5","article-title":"The challenges of anaesthesia and pain relief in hip 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Med"},{"key":"2025101110241670000_48.11.535.7","doi-asserted-by":"publisher","DOI":"10.1093\/gerona\/58.1.M76"},{"key":"2025101110241670000_48.11.535.8","article-title":"Peripheral nerve blocks for hip fractures","volume":"5","author":"Guay","year":"2017","journal-title":"Cochrane Database Syst Rev"},{"key":"2025101110241670000_48.11.535.9","doi-asserted-by":"crossref","first-page":"201010582211062","DOI":"10.1177\/20101058221106282","article-title":"Interventional therapies for management of hip fracture pain peri-operatively: a review article","volume":"31","author":"Lim","year":"2022","journal-title":"Proceedings of Singapore Healthcare"},{"key":"2025101110241670000_48.11.535.10","doi-asserted-by":"publisher","DOI":"10.1097\/AAP.0000000000000847"},{"key":"2025101110241670000_48.11.535.11","doi-asserted-by":"crossref","DOI":"10.1213\/XAA.0000000000001320","article-title":"Continuous pericapsular nerve group block for hip surgery: a case series","volume":"14","author":"Singh","year":"2020","journal-title":"A A Pract"},{"key":"2025101110241670000_48.11.535.12","article-title":"Pericapsular nerve group block: an excellent option for analgesia for positional pain in hip fractures","volume":"2020","author":"Acharya","year":"2020","journal-title":"Case Rep Anesthesiol"},{"key":"2025101110241670000_48.11.535.13","doi-asserted-by":"publisher","DOI":"10.1136\/rapm-2020-101446"},{"key":"2025101110241670000_48.11.535.14","doi-asserted-by":"publisher","DOI":"10.1136\/rapm-2020-102315"},{"key":"2025101110241670000_48.11.535.15","doi-asserted-by":"crossref","first-page":"103135","DOI":"10.1016\/j.otsr.2021.103135","article-title":"Comparison of pericapsular nerve group (PENG) block with fascia iliaca compartment block (FICB) for pain control in hip fractures: a double-blind prospective randomized controlled clinical trial","volume":"108","author":"Mosaffa","year":"2022","journal-title":"Orthop Traumatol Surg 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