{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T00:17:12Z","timestamp":1793146632243,"version":"4.5.0"},"reference-count":42,"publisher":"BMJ","issue":"8","funder":[{"DOI":"10.13039\/501100004332","name":"Seoul National University Hospital","doi-asserted-by":"publisher","award":["grant no. 04-2021-0630"],"award-info":[{"award-number":["grant no. 04-2021-0630"]}],"id":[{"id":"10.13039\/501100004332","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["Reg Anesth Pain Med"],"accepted":{"date-parts":[[2023,8,29]]},"published-print":{"date-parts":[[2024,8]]},"abstract":"<jats:sec>\n                  <jats:title>Introduction<\/jats:title>\n                  <jats:p>Limited non-opioid analgesic options are available for managing postoperative pain after renal transplantation. We aimed to investigate whether the unilateral anterior quadratus lumborum (QL) block would reduce postoperative opioid consumption after living-donor renal transplantation in the context of multimodal analgesia.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>Eighty-eight adult patients undergoing living-donor renal transplantation were randomly allocated to receive the unilateral anterior QL block (30\u2009mL of ropivacaine 0.375%) or sham block (normal saline) on the operated side before emergence from anesthesia. All patients received standard multimodal analgesia, including the scheduled administration of acetaminophen and fentanyl via intravenous patient-controlled analgesia. The primary outcome was the total opioid consumption during the first 24\u2009hours after transplantation. The secondary outcomes included pain scores, time to first opioid administration, cutaneous distribution of sensory blockade, motor weakness, nausea\/vomiting, quality of recovery scores, time to first ambulation, and length of hospital stay.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>The total opioid consumption in the first 24\u2009hours after transplantation did not differ significantly between the intervention and control groups (median (IQR), 160.5 (78\u2013249.8) vs 187.5 (93\u2013309) oral morphine milligram equivalent; median difference (95% CI), \u221227 (\u221278 to 24), p=0.29). No differences were observed in the secondary outcomes.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>The anterior QL block did not reduce opioid consumption in patients receiving multimodal analgesia after living-donor renal transplantation. Our findings do not support the routine administration of the anterior QL block in this surgical population.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Trial registration number<\/jats:title>\n                  <jats:p>\n                     <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"clintrialgov\" xlink:href=\"NCT04908761\">NCT04908761<\/jats:ext-link>.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1136\/rapm-2023-104788","type":"journal-article","created":{"date-parts":[[2023,9,13]],"date-time":"2023-09-13T21:55:11Z","timestamp":1694642111000},"page":"550-557","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":13,"title":["Anterior quadratus lumborum block for analgesia after living-donor renal transplantation: a double-blinded randomized controlled trial"],"prefix":"10.1136","volume":"49","clinical-trial-number":[{"clinical-trial-number":"nct04908761","registry":"10.18810\/clinical-trials-gov"},{"clinical-trial-number":"nct04908761","registry":"10.18810\/clinical-trials-gov"}],"author":[{"given":"Youngwon","family":"Kim","sequence":"first","affiliation":[{"name":"Department of Anesthesiology and Pain Medicine and Anesthesia and Pain Research Institute, Yonsei University College of Medicine, Seoul, Korea (the Republic of)"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3738-0081","authenticated-orcid":false,"given":"Jin-Tae","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Pain Medicine, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea (the Republic of)"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seong-Mi","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Pain Medicine, Asan Medical Center, Ulsan University College of Medicine, Seoul, Korea (the Republic of)"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Won Ho","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Pain Medicine, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea (the Republic of)"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahram","family":"Han","sequence":"additional","affiliation":[{"name":"Department of Surgery, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea (the Republic of)"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jongwon","family":"Ha","sequence":"additional","affiliation":[{"name":"Department of Surgery, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea (the Republic of)"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sangil","family":"Min","sequence":"additional","affiliation":[{"name":"Department of Surgery, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea (the Republic of)"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4670-253X","authenticated-orcid":false,"given":"Sun-Kyung","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Pain Medicine and Anesthesia and Pain Research Institute, Yonsei University College of Medicine, Seoul, Korea (the Republic of)"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2023,9,13]]},"reference":[{"key":"2025101111085096000_49.8.550.1","doi-asserted-by":"publisher","DOI":"10.1016\/j.transproceed.2012.12.014"},{"key":"2025101111085096000_49.8.550.2","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1016\/j.anclin.2017.04.005","article-title":"Anesthesia for kidney and Pancreas transplantation","volume":"35","author":"Mittel","year":"2017","journal-title":"Anesthesiol Clin"},{"key":"2025101111085096000_49.8.550.3","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1016\/j.ijsu.2020.05.073","article-title":"The efficacy of transversus abdominis plane block with or without dexmedetomidine for postoperative analgesia in renal transplantation. A randomized controlled trial","volume":"79","author":"Yang","year":"2020","journal-title":"Int J Surg"},{"key":"2025101111085096000_49.8.550.4","first-page":"5","article-title":"Robotic kidney transplantation: Current status and future perspectives","volume":"69","author":"Territo","year":"2017","journal-title":"Minerva Urol Nefrol"},{"key":"2025101111085096000_49.8.550.5","doi-asserted-by":"crossref","first-page":"1222","DOI":"10.1111\/anae.12704","article-title":"A randomised controlled trial of ultrasound-guided transversus abdominis plane block for renal transplantation","volume":"69","author":"Gulyam Kuruba","year":"2014","journal-title":"Anaesthesia"},{"key":"2025101111085096000_49.8.550.6","doi-asserted-by":"crossref","first-page":"261","DOI":"10.4103\/sja.SJA_598_17","article-title":"Evaluation of transversus abdominis plane block for renal transplant recipients - A meta-analysis and trial sequential analysis of published 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