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It is our goal that Part II of this series provides valid guidance to authors and peer reviewers who conduct systematic reviews to adhere to important constructs of transparency, structure, reproducibility, and accountability. This will likely result in more rigorous systematic reviews being submitted for publication to the journals like <jats:italic>Regional Anesthesia &amp; Pain Medicine<\/jats:italic> and <jats:italic>Anesthesia &amp; Analgesia<\/jats:italic>.<\/jats:p>","DOI":"10.1136\/rapm-2023-104802","type":"journal-article","created":{"date-parts":[[2023,11,9]],"date-time":"2023-11-09T09:35:18Z","timestamp":1699522518000},"page":"403-422","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":23,"title":["Systematic reviews and meta-analyses in regional anesthesia and pain medicine (Part II): guidelines for performing the systematic review"],"prefix":"10.1136","volume":"49","author":[{"given":"Ryan S","family":"D\u2019Souza","sequence":"first","affiliation":[{"name":"Department of Anesthesiology and Perioperative Medicine, Mayo Clinic Hospital, Rochester, Minnesota, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael J","family":"Barrington","sequence":"additional","affiliation":[{"name":"Department of Anesthesia and Perioperative Pain Medicine, Oregon Health & Sciences University, Portland, Oregon, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ananda","family":"Sen","sequence":"additional","affiliation":[{"name":"Departments of Biostatistics and Family Medicine, University of Michigan, Ann Arbor, Michigan, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edward J","family":"Mascha","sequence":"additional","affiliation":[{"name":"Departments of Quantitative Health Sciences and Outcomes Research, Cleveland Clinic, Cleveland, Ohio, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"George A","family":"Kelley","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Biostatistics, West Virginia University, Morgantown, West Virginia, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2023,11,9]]},"reference":[{"key":"2025101109561729000_49.6.403.1","unstructured":"Lefebvre C , Glanville J , Briscoe S , et al . 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