{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,10]],"date-time":"2026-11-10T00:39:25Z","timestamp":1794271165293,"version":"4.9.0"},"reference-count":310,"publisher":"BMJ","issue":"11","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["Reg Anesth Pain Med"],"accepted":{"date-parts":[[2024,11,14]]},"published-print":{"date-parts":[[2026,11]]},"DOI":"10.1136\/rapm-2024-105766","type":"journal-article","created":{"date-parts":[[2025,1,29]],"date-time":"2025-01-29T13:14:17Z","timestamp":1738156457000},"page":"1233-1261","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":84,"title":["Regional anesthesia in the patient receiving antithrombotic or thrombolytic therapy: American Society of Regional Anesthesia and Pain Medicine Evidence-Based Guidelines (fifth edition)"],"prefix":"10.1136","volume":"51","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2997-5445","authenticated-orcid":false,"given":"Sandra L","family":"Kopp","sequence":"first","affiliation":[{"name":"Anesthesiology and Perioperative Medicine, Mayo Clinic, Rochester, Minnesota, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erik","family":"Vandermeulen","sequence":"additional","affiliation":[{"name":"Universitaire Ziekenhuizen Leuven, Leuven, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert D","family":"McBane","sequence":"additional","affiliation":[{"name":"Cardiovascular Medicine and Hematology, Mayo Clinic, Rochester, Minnesota, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8190-8314","authenticated-orcid":false,"given":"Anahi","family":"Perlas","sequence":"additional","affiliation":[{"name":"Anesthesia and Pain Management, Toronto Western Hospital, Toronto, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8337-3811","authenticated-orcid":false,"given":"Lisa","family":"Leffert","sequence":"additional","affiliation":[{"name":"Anesthesia, Critical Care & Pain Medicine, Yale School of Medicine, New Haven, Connecticut, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Terese","family":"Horlocker","sequence":"additional","affiliation":[{"name":"Anesthesiology and Perioperative Medicine, Mayo Clinic, Rochester, Minnesota, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2025,1,29]]},"reference":[{"key":"2026110502150573000_51.11.1233.1","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-200209000-00032"},{"key":"2026110502150573000_51.11.1233.2","doi-asserted-by":"publisher","DOI":"10.1136\/rapm-00115550-199823062-00003"},{"key":"2026110502150573000_51.11.1233.3","doi-asserted-by":"publisher","DOI":"10.1136\/rapm-00115550-199823020-00009"},{"key":"2026110502150573000_51.11.1233.4","doi-asserted-by":"publisher","DOI":"10.1053\/rapm.2003.50046"},{"key":"2026110502150573000_51.11.1233.5","doi-asserted-by":"publisher","DOI":"10.1136\/rapm-00115550-199823062-00006"},{"key":"2026110502150573000_51.11.1233.6","doi-asserted-by":"publisher","DOI":"10.1136\/rapm-00115550-199823020-00007"},{"key":"2026110502150573000_51.11.1233.7","doi-asserted-by":"publisher","DOI":"10.1136\/rapm-00115550-199823062-00004"},{"key":"2026110502150573000_51.11.1233.8","doi-asserted-by":"publisher","DOI":"10.1097\/AAP.0b013e3181c15c70"},{"key":"2026110502150573000_51.11.1233.9","doi-asserted-by":"publisher","DOI":"10.1097\/AAP.0000000000000763"},{"key":"2026110502150573000_51.11.1233.10","doi-asserted-by":"publisher","DOI":"10.1213\/ANE.0000000000002530"},{"key":"2026110502150573000_51.11.1233.11","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1097\/EJA.0000000000001600","article-title":"Regional anaesthesia in patients on antithrombotic drugs: Joint ESAIC\/ESRA guidelines","volume":"39","author":"Kietaibl","year":"2022","journal-title":"Eur J Anaesthesiol"},{"key":"2026110502150573000_51.11.1233.12","doi-asserted-by":"crossref","first-page":"1127","DOI":"10.1016\/j.chest.2022.08.004","article-title":"Executive Summary: Perioperative Management of Antithrombotic Therapy: An American College of Chest Physicians Clinical Practice Guideline","volume":"162","author":"Douketis","year":"2022","journal-title":"Chest"},{"key":"2026110502150573000_51.11.1233.13","doi-asserted-by":"publisher","DOI":"10.1378\/chest.08-0656"},{"key":"2026110502150573000_51.11.1233.14","doi-asserted-by":"publisher","DOI":"10.1378\/chest.11-2296"},{"key":"2026110502150573000_51.11.1233.15","doi-asserted-by":"publisher","DOI":"10.1378\/chest.11-2404"},{"key":"2026110502150573000_51.11.1233.16","doi-asserted-by":"crossref","DOI":"10.1378\/chest.11-2297","article-title":"Prevention of VTE in nonorthopedic surgical patients: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines","volume":"141","author":"Gould","year":"2012","journal-title":"Chest"},{"key":"2026110502150573000_51.11.1233.17","doi-asserted-by":"publisher","DOI":"10.1016\/j.chest.2015.11.026"},{"key":"2026110502150573000_51.11.1233.18","doi-asserted-by":"publisher","DOI":"10.1016\/j.chest.2021.07.055"},{"key":"2026110502150573000_51.11.1233.19","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjmed.2014.03.041"},{"key":"2026110502150573000_51.11.1233.20","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.167.14.1471"},{"key":"2026110502150573000_51.11.1233.21","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0000000000000769"},{"key":"2026110502150573000_51.11.1233.22","doi-asserted-by":"publisher","DOI":"10.1182\/bloodadvances.2018022954"},{"key":"2026110502150573000_51.11.1233.23","doi-asserted-by":"publisher","DOI":"10.1182\/bloodadvances.2019000975"},{"key":"2026110502150573000_51.11.1233.24","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-155-9-201111010-00011"},{"key":"2026110502150573000_51.11.1233.25","doi-asserted-by":"publisher","DOI":"10.1111\/j.1538-7836.2010.04044.x"},{"key":"2026110502150573000_51.11.1233.26","doi-asserted-by":"publisher","DOI":"10.1378\/chest.10-1944"},{"key":"2026110502150573000_51.11.1233.27","doi-asserted-by":"crossref","first-page":"e56","DOI":"10.1055\/s-0037-1603929","article-title":"The IMPROVEDD VTE Risk Score: Incorporation of D-Dimer into the IMPROVE Score to Improve Venous Thromboembolism Risk Stratification","volume":"1","author":"Gibson","year":"2017","journal-title":"TH Open"},{"key":"2026110502150573000_51.11.1233.28","doi-asserted-by":"publisher","DOI":"10.1378\/chest.09-3081"},{"key":"2026110502150573000_51.11.1233.29","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1816150"},{"key":"2026110502150573000_51.11.1233.30","article-title":"Combined intermittent pneumatic leg compression and pharmacological prophylaxis for prevention of venous thromboembolism","volume":"1","author":"Kakkos","year":"2022","journal-title":"Cochrane Database Syst Rev"},{"key":"2026110502150573000_51.11.1233.31","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0b013e3181b7fca6"},{"key":"2026110502150573000_51.11.1233.32","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamcollsurg.2007.02.072"},{"key":"2026110502150573000_51.11.1233.33","doi-asserted-by":"crossref","first-page":"941","DOI":"10.1001\/jamasurg.2015.1841","article-title":"Validation of the Caprini Venous Thromboembolism Risk Assessment Model in Critically Ill Surgical Patients","volume":"150","author":"Obi","year":"2015","journal-title":"JAMA Surg"},{"key":"2026110502150573000_51.11.1233.34","doi-asserted-by":"crossref","first-page":"1029","DOI":"10.1016\/j.jamcollsurg.2016.12.054","article-title":"Evaluation of a Standardized Risk-Based Venous Thromboembolism Prophylaxis Protocol in the Setting of Thyroid and Parathyroid Surgery","volume":"224","author":"Macht","year":"2017","journal-title":"J Am Coll Surg"},{"key":"2026110502150573000_51.11.1233.35","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamcollsurg.2010.08.018"},{"key":"2026110502150573000_51.11.1233.36","doi-asserted-by":"publisher","DOI":"10.1016\/j.fas.2013.11.002"},{"key":"2026110502150573000_51.11.1233.37","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/j.jvsv.2015.09.004","article-title":"Validation of the Caprini risk assessment model for venous thromboembolism in high-risk surgical patients in the background of standard prophylaxis","volume":"4","author":"Lobastov","year":"2016","journal-title":"J Vasc Surg Venous Lymphat Disord"},{"key":"2026110502150573000_51.11.1233.38","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21708"},{"key":"2026110502150573000_51.11.1233.39","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2007-10-116327"},{"key":"2026110502150573000_51.11.1233.40","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1814468"},{"key":"2026110502150573000_51.11.1233.41","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1814630"},{"key":"2026110502150573000_51.11.1233.42","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1200\/JCO.19.01461","article-title":"Venous Thromboembolism Prophylaxis and Treatment in Patients With Cancer: ASCO Clinical Practice Guideline Update","volume":"38","author":"Key","year":"2020","journal-title":"JCO"},{"key":"2026110502150573000_51.11.1233.43","doi-asserted-by":"crossref","first-page":"1772","DOI":"10.1111\/jth.14564","article-title":"The use of direct oral anticoagulants for primary thromboprophylaxis in ambulatory cancer patients: Guidance from the SSC of the ISTH","volume":"17","author":"Wang","year":"2019","journal-title":"J Thromb Haemost"},{"key":"2026110502150573000_51.11.1233.44","doi-asserted-by":"publisher","DOI":"10.1007\/s11606-020-05904-0"},{"key":"2026110502150573000_51.11.1233.45","doi-asserted-by":"publisher","DOI":"10.1161\/cir.0000000000001052"},{"key":"2026110502150573000_51.11.1233.46","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.111.090464"},{"key":"2026110502150573000_51.11.1233.47","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.113.005754"},{"key":"2026110502150573000_51.11.1233.48","doi-asserted-by":"publisher","DOI":"10.1378\/chest.11-2298"},{"key":"2026110502150573000_51.11.1233.49","doi-asserted-by":"crossref","first-page":"1966","DOI":"10.1111\/jth.14598","article-title":"Scientific and Standardization Committee Communication: Guidance document on the periprocedural management of patients on chronic oral anticoagulant therapy: Recommendations for standardized reporting of procedural\/surgical bleed risk and patient-specific thromboembolic risk","volume":"17","author":"Spyropoulos","year":"2019","journal-title":"J Thromb Haemost"},{"key":"2026110502150573000_51.11.1233.50","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.164.12.1319"},{"key":"2026110502150573000_51.11.1233.51","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1186\/s13741-020-00170-4","article-title":"Markedly increased risk of postoperative bleeding complications during perioperative bridging anticoagulation in general and visceral surgery","volume":"9","author":"Lock","year":"2020","journal-title":"Perioper Med"},{"key":"2026110502150573000_51.11.1233.52","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-200410000-00021"},{"key":"2026110502150573000_51.11.1233.53","doi-asserted-by":"crossref","first-page":"1165","DOI":"10.1213\/00000539-199412000-00024","article-title":"Anticoagulants and spinal-epidural anesthesia","volume":"79","author":"Vandermeulen","year":"1994","journal-title":"Anesth Analg"},{"key":"2026110502150573000_51.11.1233.54","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.143.10.990"},{"key":"2026110502150573000_51.11.1233.55","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1097\/EJA.0000000000000729","article-title":"European Guidelines on perioperative venous thromboembolism prophylaxis: Executive summary","volume":"35","author":"Afshari","year":"2018","journal-title":"Eur J Anaesthesiol"},{"key":"2026110502150573000_51.11.1233.56","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1097\/EJA.0000000000000702","article-title":"European guidelines on perioperative venous thromboembolism prophylaxis","volume":"35","author":"Samama","year":"2018","journal-title":"Eur J Anaesthesiol"},{"key":"2026110502150573000_51.11.1233.57","doi-asserted-by":"crossref","first-page":"1469","DOI":"10.1001\/jamainternmed.2019.2431","article-title":"Perioperative Management of Patients With Atrial Fibrillation Receiving a Direct Oral Anticoagulant","volume":"179","author":"Douketis","year":"2019","journal-title":"JAMA Intern Med"},{"key":"2026110502150573000_51.11.1233.58","doi-asserted-by":"publisher","DOI":"10.1111\/jth.13912"},{"key":"2026110502150573000_51.11.1233.59","doi-asserted-by":"crossref","first-page":"2431","DOI":"10.1093\/eurheartj\/ehx403","article-title":"Predictors of pre-procedural concentrations of direct oral anticoagulants: a prospective multicentre study","volume":"38","author":"Godier","year":"2017","journal-title":"Eur Heart J"},{"key":"2026110502150573000_51.11.1233.60","doi-asserted-by":"crossref","DOI":"10.3390\/biomedicines9050445","article-title":"Laboratory Monitoring of Direct Oral Anticoagulants (DOACs)","volume":"9","author":"Dunois","year":"2021","journal-title":"Biomedicines"},{"key":"2026110502150573000_51.11.1233.61","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1213\/ANE.0000000000005114","article-title":"Heparin Anti-Xa Activity, a Readily Available Unique Test to Quantify Apixaban, Rivaroxaban, Fondaparinux, and Danaparoid Levels","volume":"132","author":"Boissier","year":"2021","journal-title":"Anesth Analg"},{"key":"2026110502150573000_51.11.1233.62","doi-asserted-by":"publisher","DOI":"10.1160\/TH10-03-0204"},{"key":"2026110502150573000_51.11.1233.63","doi-asserted-by":"publisher","DOI":"10.1055\/s-0038-1627480"},{"key":"2026110502150573000_51.11.1233.64","doi-asserted-by":"publisher","DOI":"10.1111\/bjh.13810"},{"key":"2026110502150573000_51.11.1233.65","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1016\/j.transci.2016.05.016","article-title":"An update on laboratory measurements of Dabigatran: Smart specific and calibrated dedicated assays for measuring anti-IIa activity in plasma","volume":"54","author":"Amiral","year":"2016","journal-title":"Transfus Apher Sci"},{"key":"2026110502150573000_51.11.1233.66","doi-asserted-by":"publisher","DOI":"10.1111\/bcp.12364"},{"key":"2026110502150573000_51.11.1233.67","doi-asserted-by":"crossref","first-page":"862","DOI":"10.1160\/TH14-09-0808","article-title":"Estimation of dabigatran plasma concentrations in the perioperative setting. An ex vivo study using dedicated coagulation assays","volume":"113","author":"Douxfils","year":"2015","journal-title":"Thromb Haemost"},{"key":"2026110502150573000_51.11.1233.68","doi-asserted-by":"publisher","DOI":"10.1111\/bjh.12975"},{"key":"2026110502150573000_51.11.1233.69","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1016\/j.sjpain.2016.11.008","article-title":"Neuraxial blocks and spinal haematoma: Review of 166 case reports published 1994-2015. Part 1: Demographics and risk-factors","volume":"15","author":"Lagerkranser","year":"2017","journal-title":"Scand J Pain"},{"key":"2026110502150573000_51.11.1233.70","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1016\/j.sjpain.2016.11.009","article-title":"Neuraxial blocks and spinal haematoma: Review of 166 cases published 1994","volume":"15","author":"Lagerkranser","year":"2015","journal-title":"Scand J Pain"},{"key":"2026110502150573000_51.11.1233.71","doi-asserted-by":"crossref","DOI":"10.1093\/jscr\/rjz115","article-title":"Spontaneous thoracic spinal subdural hematoma associated with apixaban therapy","volume":"2019","author":"Ardebol","year":"2019","journal-title":"J Surg Case Rep"},{"key":"2026110502150573000_51.11.1233.72","article-title":"Spontaneous Spinal Epidural Hematoma in a Patient on Apixaban for Nonvalvular Atrial Fibrillation","volume":"2020","author":"El Alayli","year":"2020","journal-title":"Case Rep Hematol"},{"key":"2026110502150573000_51.11.1233.73","doi-asserted-by":"crossref","first-page":"1215","DOI":"10.1007\/s11239-021-02462-y","article-title":"A rare case of non-traumatic spinal epidural hematoma in lumbar region associated with apixaban therapy","volume":"52","author":"Krupa","year":"2021","journal-title":"J Thromb Thrombol"},{"key":"2026110502150573000_51.11.1233.74","article-title":"Spontaneous Spinal Epidural Hematoma Associated With Apixaban Therapy: A Report of two Cases","volume":"12","author":"Mezzacappa","year":"2020","journal-title":"Cureus"},{"key":"2026110502150573000_51.11.1233.75","doi-asserted-by":"crossref","DOI":"10.25259\/SNI_434_2021","article-title":"Spontaneous thoracolumbar epidural hematoma in an apixaban anticoagulated patient","volume":"12","author":"Theofanopoulos","year":"2021","journal-title":"Surg Neurol Int"},{"key":"2026110502150573000_51.11.1233.76","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1016\/j.wneu.2020.01.240","article-title":"Spontaneous Spinal Epidural Hematoma After Normal Spontaneous Delivery with Epidural Analgesia: Case Report and Literature Review","volume":"137","author":"Zheng","year":"2020","journal-title":"World Neurosurg"},{"key":"2026110502150573000_51.11.1233.77","doi-asserted-by":"crossref","DOI":"10.2106\/JBJS.CC.M.00011","article-title":"Spinal Epidural Hematoma Following Epidural Steroid Injection in a Patient Treated with Dabigatran: A Case Report","volume":"3","author":"Caputo","year":"2013","journal-title":"JBJS Case Connect"},{"key":"2026110502150573000_51.11.1233.78","doi-asserted-by":"publisher","DOI":"10.1097\/AAP.0000000000000360"},{"key":"2026110502150573000_51.11.1233.79","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/euab065"},{"key":"2026110502150573000_51.11.1233.80","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2044.2007.05195.x"},{"key":"2026110502150573000_51.11.1233.81","doi-asserted-by":"publisher","DOI":"10.2174\/138161210793563338"},{"key":"2026110502150573000_51.11.1233.82","doi-asserted-by":"publisher","DOI":"10.1111\/jth.13227"},{"key":"2026110502150573000_51.11.1233.83","doi-asserted-by":"publisher","DOI":"10.1016\/j.acvd.2013.04.009S1875-2136(13)00167-8"},{"key":"2026110502150573000_51.11.1233.84","doi-asserted-by":"publisher","DOI":"10.1186\/s13054-015-0930-9"},{"key":"2026110502150573000_51.11.1233.85","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1111\/jth.13178","article-title":"Effect of standardized perioperative dabigatran interruption on the residual anticoagulation effect at the time of surgery or procedure","volume":"14","author":"Douketis","year":"2016","journal-title":"J Thromb Haemost"},{"key":"2026110502150573000_51.11.1233.86","unstructured":"BMS . Apixaban full prescribing information. Available: http:\/\/packageinserts.bms.com\/pi\/pi_eliquis.pdf [Accessed 13 Mar 2024]."},{"key":"2026110502150573000_51.11.1233.87","unstructured":"Savaysa: full prescribing information. Available: http:\/\/dsi.com\/prescribing-information-portlet\/getPIContent?productName=Savaysa&inline=true [Accessed 18 Aug 2022]."},{"key":"2026110502150573000_51.11.1233.88","unstructured":"Bevixxa: full prescribing information. Available: https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2017\/208383s000lbl.pdf [Accessed 18 Aug 2022]."},{"key":"2026110502150573000_51.11.1233.89","unstructured":"Rivaroxaban: full prescribing information. Available: https:\/\/www.janssenlabels.com\/package-insert\/product-monograph\/prescribing-information\/XARELTO-pi.pdf [Accessed 18 Aug 2022]."},{"key":"2026110502150573000_51.11.1233.90","unstructured":"Pradaxa: full prescribing infomation. Available: http:\/\/docs.boehringer-ingelheim.com\/Prescribing%20Information\/PIs\/Pradaxa\/Pradaxa.pdf [Accessed 18 Aug 2022]."},{"key":"2026110502150573000_51.11.1233.91","doi-asserted-by":"publisher","DOI":"10.1136\/heartjnl-2016-310581"},{"key":"2026110502150573000_51.11.1233.92","first-page":"1015","article-title":"Management of bleeding complications in patients on new oral anticoagulants","volume":"2","author":"Gonsalves","year":"2014","journal-title":"J Hematol Transfus"},{"key":"2026110502150573000_51.11.1233.93","doi-asserted-by":"publisher","DOI":"10.1038\/nm.3102"},{"key":"2026110502150573000_51.11.1233.94","unstructured":"Andexxa: full prescribing information. Available: https:\/\/www.andexxa.com\/prescribing-information.html [Accessed 18 Aug 2022]."},{"key":"2026110502150573000_51.11.1233.95","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1607887"},{"key":"2026110502150573000_51.11.1233.96","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1814051"},{"key":"2026110502150573000_51.11.1233.97","doi-asserted-by":"crossref","first-page":"2096","DOI":"10.1161\/STROKEAHA.120.030565","article-title":"Hemostatic Efficacy and Anti-FXa (Factor Xa) Reversal With Andexanet Alfa in Intracranial Hemorrhage: ANNEXA-4 Substudy","volume":"52","author":"Demchuk","year":"2021","journal-title":"Stroke"},{"key":"2026110502150573000_51.11.1233.98","doi-asserted-by":"crossref","first-page":"998","DOI":"10.1055\/s-0041-1740180","article-title":"Andexanet Alfa for Specific Anticoagulation Reversal in Patients with Acute Bleeding during Treatment with Edoxaban","volume":"122","author":"Benz","year":"2022","journal-title":"Thromb Haemost"},{"key":"2026110502150573000_51.11.1233.99","first-page":"1049","article-title":"Andexanet Alfa: First Global Approval","volume":"78","author":"Heo","year":"2018","journal-title":"Drugs (Abingdon Engl)"},{"key":"2026110502150573000_51.11.1233.100","unstructured":"Praxbind full prescribing information. 2015. Available: http:\/\/docs.boehringer-ingelheim.com\/Prescribing%20Information\/PIs\/Praxbind\/Praxbind.pdf [Accessed 18 Aug 2022]."},{"key":"2026110502150573000_51.11.1233.101","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1502000"},{"key":"2026110502150573000_51.11.1233.102","first-page":"391","article-title":"Management of bleeding and emergency invasive procedures in patients on dabigatran: Updated guidelines from the French Working Group on Perioperative Haemostasis (GIHP) \u2013 September 2016","volume":"37","author":"Albaladejo","year":"2018","journal-title":"Anaesth Crit Care Pain Med"},{"key":"2026110502150573000_51.11.1233.103","doi-asserted-by":"crossref","first-page":"662","DOI":"10.1016\/j.ajem.2016.10.068","article-title":"Emergency LP in a patient receiving dabigatran after antagonization with idarucizumab","volume":"35","author":"Braemswig","year":"2017","journal-title":"Am J Emerg Med"},{"key":"2026110502150573000_51.11.1233.104","doi-asserted-by":"crossref","first-page":"40","DOI":"10.2174\/1574886313666180816125234","article-title":"Dabigatran Reversal with Idarucizumab in an Emergency Lumbar Puncture: A Case Report","volume":"14","author":"Spagnolello","year":"2019","journal-title":"Curr Drug Saf"},{"key":"2026110502150573000_51.11.1233.105","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1097\/ALN.0000000000001631","article-title":"Management of Severe Bleeding in Patients Treated with Direct Oral Anticoagulants: An Observational Registry Analysis","volume":"127","author":"Albaladejo","year":"2017","journal-title":"Anesthesiology"},{"key":"2026110502150573000_51.11.1233.106","doi-asserted-by":"publisher","DOI":"10.1055\/s-0038-1636541"},{"key":"2026110502150573000_51.11.1233.107","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/j.chest.2017.02.009","article-title":"Direct Oral Anticoagulant- or Warfarin-Related Major Bleeding: Characteristics, Reversal Strategies, and Outcomes From a Multicenter Observational Study","volume":"152","author":"Xu","year":"2017","journal-title":"Chest"},{"key":"2026110502150573000_51.11.1233.108","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1177\/0885066619882909","article-title":"Four-Factor Prothrombin Complex Concentrate for the Reversal of Direct Oral Anticoagulants","volume":"36","author":"Zada","year":"2021","journal-title":"J Intensive Care Med"},{"key":"2026110502150573000_51.11.1233.109","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2017-05-782060"},{"key":"2026110502150573000_51.11.1233.110","doi-asserted-by":"crossref","DOI":"10.1186\/s13054-022-04043-8","article-title":"Andexanet alfa versus four-factor prothrombin complex concentrate for the reversal of apixaban- or rivaroxaban-associated intracranial hemorrhage: a propensity score-overlap weighted analysis","volume":"26","author":"Costa","year":"2022","journal-title":"Crit Care"},{"key":"2026110502150573000_51.11.1233.111","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajem.2022.02.029"},{"key":"2026110502150573000_51.11.1233.112","doi-asserted-by":"publisher","DOI":"10.1378\/chest.108.4_Supplement.258S"},{"key":"2026110502150573000_51.11.1233.113","doi-asserted-by":"publisher","DOI":"10.1378\/chest.11-2291"},{"key":"2026110502150573000_51.11.1233.114","doi-asserted-by":"publisher","DOI":"10.1002\/j.1875-9114.2011.01049.x"},{"key":"2026110502150573000_51.11.1233.115","doi-asserted-by":"publisher","DOI":"10.1016\/S1053-0770(97)90247-0"},{"key":"2026110502150573000_51.11.1233.116","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM197303152881103"},{"key":"2026110502150573000_51.11.1233.117","doi-asserted-by":"publisher","DOI":"10.1378\/chest.08-0674"},{"key":"2026110502150573000_51.11.1233.118","doi-asserted-by":"publisher","DOI":"10.1182\/bloodadvances.2018024489"},{"key":"2026110502150573000_51.11.1233.119","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM200104263441704"},{"key":"2026110502150573000_51.11.1233.120","doi-asserted-by":"publisher","DOI":"10.1378\/chest.122.1.37"},{"key":"2026110502150573000_51.11.1233.121","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-135-7-200110020-00009"},{"key":"2026110502150573000_51.11.1233.122","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-136-3-200202050-00009"},{"key":"2026110502150573000_51.11.1233.123","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.12.6.879"},{"key":"2026110502150573000_51.11.1233.124","doi-asserted-by":"publisher","DOI":"10.1007\/BF03011675"},{"key":"2026110502150573000_51.11.1233.125","first-page":"139","article-title":"Belgian guidelines concerning central neural blockade in patients with drug-induced alteration of coagulation: an update","volume":"56","author":"Vandermeulen","year":"2005","journal-title":"Acta Anaesthesiol Belg"},{"key":"2026110502150573000_51.11.1233.126","doi-asserted-by":"crossref","first-page":"618","DOI":"10.1097\/00000542-198155060-00002","article-title":"Anticoagulation Following Placement of Epidural and Subarachnoid Catheters","volume":"55","author":"Rao","year":"1981","journal-title":"Anesthesiology"},{"key":"2026110502150573000_51.11.1233.127","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000140675.85342.1B"},{"key":"2026110502150573000_51.11.1233.128","doi-asserted-by":"publisher","DOI":"10.1097\/00000539-199706000-00008"},{"key":"2026110502150573000_51.11.1233.129","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2044.1991.tb09705.x"},{"key":"2026110502150573000_51.11.1233.130","doi-asserted-by":"publisher","DOI":"10.1007\/BF03013437"},{"key":"2026110502150573000_51.11.1233.131","doi-asserted-by":"crossref","first-page":"1356","DOI":"10.12659\/AJCR.917716","article-title":"Spinal Epidural Hematoma Following Epidural Catheter Removal in a Patient with Postoperative Urgent Coronary Intervention and Intra-Aortic Balloon Pumping (IABP): A Case Report","volume":"20","author":"Mimata","year":"2019","journal-title":"Am J Case Rep"},{"key":"2026110502150573000_51.11.1233.132","doi-asserted-by":"publisher","DOI":"10.1097\/00000539-200005000-00004"},{"key":"2026110502150573000_51.11.1233.133","doi-asserted-by":"publisher","DOI":"10.1097\/00000539-200005000-00002"},{"key":"2026110502150573000_51.11.1233.134","doi-asserted-by":"publisher","DOI":"10.1016\/S1053-0770(98)90326-3"},{"key":"2026110502150573000_51.11.1233.135","doi-asserted-by":"publisher","DOI":"10.1016\/S1053-0770(96)80062-0"},{"key":"2026110502150573000_51.11.1233.136","doi-asserted-by":"publisher","DOI":"10.1016\/S1053-0770(96)80063-2"},{"key":"2026110502150573000_51.11.1233.137","doi-asserted-by":"publisher","DOI":"10.1213\/01.ANE.0000103267.37895.5B"},{"key":"2026110502150573000_51.11.1233.138","doi-asserted-by":"publisher","DOI":"10.1378\/chest.117.2.551"},{"key":"2026110502150573000_51.11.1233.139","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198805053181805"},{"key":"2026110502150573000_51.11.1233.140","doi-asserted-by":"crossref","first-page":"1215","DOI":"10.1213\/ANE.0000000000000437","article-title":"Epidurals in patients receiving thromboprophylaxis with unfractionated heparin three times a day: the value of activated partial thromboplastin time testing","volume":"119","author":"Pace","year":"2014","journal-title":"Anesth Analg"},{"key":"2026110502150573000_51.11.1233.141","doi-asserted-by":"publisher","DOI":"10.1097\/AAP.0b013e31826a8d10"},{"key":"2026110502150573000_51.11.1233.142","doi-asserted-by":"crossref","first-page":"e57","DOI":"10.1213\/ANE.0000000000003603","article-title":"Epidural Analgesia and Subcutaneous Heparin 3 Times Daily in Cancer Patients With Acute Postoperative Pain","volume":"127","author":"Su","year":"2018","journal-title":"Anesth Analg"},{"key":"2026110502150573000_51.11.1233.143","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1213\/XAA.0000000000000492","article-title":"Recognition of a Thoracic Epidural Hematoma in the Setting of Transient Paralysis","volume":"8","author":"VanderWielen","year":"2017","journal-title":"A A Case Rep"},{"key":"2026110502150573000_51.11.1233.144","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2044.1997.63-az0065.x"},{"key":"2026110502150573000_51.11.1233.145","doi-asserted-by":"publisher","DOI":"10.1007\/s11239-015-1309-0"},{"key":"2026110502150573000_51.11.1233.146","doi-asserted-by":"publisher","DOI":"10.1378\/chest.126.3_suppl.627S"},{"key":"2026110502150573000_51.11.1233.147","doi-asserted-by":"crossref","first-page":"1066","DOI":"10.1056\/NEJM197605062941917","article-title":"Letter: Monitoring during low-dose heparin prophylaxis","volume":"294","author":"Cooke","year":"1976","journal-title":"N Engl J Med"},{"key":"2026110502150573000_51.11.1233.148","doi-asserted-by":"crossref","first-page":"612","DOI":"10.1097\/00001573-199409000-00017","article-title":"Low molecular weight heparins","volume":"9","author":"Cosmi","year":"1994","journal-title":"Curr Opin Cardiol"},{"key":"2026110502150573000_51.11.1233.149","doi-asserted-by":"publisher","DOI":"10.1378\/chest.08-0689"},{"key":"2026110502150573000_51.11.1233.150","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1097\/00001721-199410000-00018","article-title":"Protamine neutralization of intravenous and subcutaneous low-molecular-weight heparin (tinzaparin, Logiparin). An experimental investigation in healthy volunteers","volume":"5","author":"Holst","year":"1994","journal-title":"Blood Coagul Fibrinolysis"},{"key":"2026110502150573000_51.11.1233.151","doi-asserted-by":"publisher","DOI":"10.1093\/ajcp\/103.5.642"},{"key":"2026110502150573000_51.11.1233.152","doi-asserted-by":"crossref","first-page":"940","DOI":"10.1055\/s-0038-1651032","article-title":"The relationship between anti-factor Xa level and clinical outcome in patients receiving enoxaparine low molecular weight heparin to prevent deep vein thrombosis after hip replacement","volume":"62","author":"Levine","year":"1989","journal-title":"Thromb Haemost"},{"key":"2026110502150573000_51.11.1233.153","doi-asserted-by":"publisher","DOI":"10.1136\/rapm-00115550-199823062-00009"},{"key":"2026110502150573000_51.11.1233.154","first-page":"245","article-title":"Dosing of Enoxaparin in Renal Impairment","volume":"42","author":"Shaikh","year":"2017","journal-title":"P T"},{"key":"2026110502150573000_51.11.1233.155","doi-asserted-by":"publisher","DOI":"10.1097\/AAP.0000000000000617"},{"key":"2026110502150573000_51.11.1233.156","doi-asserted-by":"publisher","DOI":"10.1136\/rapm-2022-104079"},{"key":"2026110502150573000_51.11.1233.157","doi-asserted-by":"publisher","DOI":"10.1136\/rapm-2023-104571"},{"key":"2026110502150573000_51.11.1233.158","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1097\/01.ccm.0000909808.50243.3e","article-title":"1020: therapeutic enoxaparin in morbidly obese patients: single-center experience","volume":"51","author":"Sharma","year":"2023","journal-title":"Crit Care Med"},{"key":"2026110502150573000_51.11.1233.159","doi-asserted-by":"publisher","DOI":"10.1177\/003335491513000614"},{"key":"2026110502150573000_51.11.1233.160","doi-asserted-by":"publisher","DOI":"10.1016\/0049-3848(79)90270-6"},{"key":"2026110502150573000_51.11.1233.161","doi-asserted-by":"crossref","first-page":"1236","DOI":"10.1016\/S0140-6736(79)91911-1","article-title":"Aspirin and bleeding-time","volume":"1","author":"Godal","year":"1979","journal-title":"Lancet"},{"key":"2026110502150573000_51.11.1233.162","doi-asserted-by":"publisher","DOI":"10.1378\/chest.11-2293"},{"key":"2026110502150573000_51.11.1233.163","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1111\/j.1600-0609.1984.tb02390.x","article-title":"Effect on platelet aggregation of oral administration of 10 non-steroidal analgesics to humans","volume":"33","author":"Cronberg","year":"1984","journal-title":"Scand J Haematol"},{"key":"2026110502150573000_51.11.1233.164","doi-asserted-by":"publisher","DOI":"10.1177\/00912700022008766"},{"key":"2026110502150573000_51.11.1233.165","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMe038191"},{"key":"2026110502150573000_51.11.1233.166","doi-asserted-by":"crossref","first-page":"201","DOI":"10.20452\/pamw.360","article-title":"Perioperative management of antithrombotic therapy","volume":"118","author":"Douketis","year":"2008","journal-title":"Pol Arch Intern Med"},{"key":"2026110502150573000_51.11.1233.167","unstructured":"Plavix prescribing information. n.d. Available: https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2010\/020839s048lbl.pdf"},{"key":"2026110502150573000_51.11.1233.168","unstructured":"Prasurgel. n.d. Available: https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2011\/022307s003lbl.pdf"},{"key":"2026110502150573000_51.11.1233.169","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2012.02.042"},{"key":"2026110502150573000_51.11.1233.170","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.109.912550"},{"key":"2026110502150573000_51.11.1233.171","first-page":"S75","article-title":"Pharmacology and clinical trials of reversibly-binding P2Y12 inhibitors","volume":"105 Suppl 1","author":"Storey","year":"2011","journal-title":"Thromb Haemost"},{"key":"2026110502150573000_51.11.1233.172","first-page":"633","article-title":"Platelet function recovery after ticagrelor withdrawal in patients awaiting urgent coronary surgery","volume":"51","author":"Hansson","year":"2017","journal-title":"Eur J Cardiothorac Surg"},{"key":"2026110502150573000_51.11.1233.173","unstructured":"Full prescribing information. Available: http:\/\/www.azpicentral.com\/brilinta\/brilinta.pdf#page=1 [Accessed 15 Feb 2023]."},{"key":"2026110502150573000_51.11.1233.174","doi-asserted-by":"publisher","DOI":"10.1177\/0091270009344986"},{"key":"2026110502150573000_51.11.1233.175","doi-asserted-by":"publisher","DOI":"10.1097\/CRD.0000000000000142"},{"key":"2026110502150573000_51.11.1233.176","unstructured":"Tummala R , Rai MP . Glycoprotein IIb\/IIIa inhibitors. StatPearls, 2023."},{"key":"2026110502150573000_51.11.1233.177","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1007\/s00540-008-0623-5","article-title":"Spinal epidural hematoma following epidural catheter removal during antiplatelet therapy with cilostazol","volume":"22","author":"Kaneda","year":"2008","journal-title":"J Anesth"},{"key":"2026110502150573000_51.11.1233.178","doi-asserted-by":"publisher","DOI":"10.1097\/00000539-200212000-00041"},{"key":"2026110502150573000_51.11.1233.179","doi-asserted-by":"publisher","DOI":"10.1097\/AAP.0000000000000026"},{"key":"2026110502150573000_51.11.1233.180","doi-asserted-by":"publisher","DOI":"10.1097\/AAP.0000000000000029"},{"key":"2026110502150573000_51.11.1233.181","doi-asserted-by":"publisher","DOI":"10.1097\/AAP.0000000000000700"},{"key":"2026110502150573000_51.11.1233.182","first-page":"745","article-title":"Clopidogrel","volume":"54","author":"Coukell","year":"1997","journal-title":"Drugs (Abingdon Engl)"},{"key":"2026110502150573000_51.11.1233.183","first-page":"505","article-title":"Inhibitors of the platelet receptor glycoprotein IIb-IIIa and complications during percutaneous coronary revascularization. Management strategies for the cardiac surgeon","volume":"40","author":"Dyke","year":"1999","journal-title":"J Cardiovasc Surg (Torino)"},{"key":"2026110502150573000_51.11.1233.184","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/S1051-0443(07)61716-3","article-title":"Platelet aggregation inhibitors for use in peripheral vascular interventions: what can we learn from the experience in the coronary arteries?","volume":"13","author":"Shlansky-Goldberg","year":"2002","journal-title":"J Vasc Interv Radiol"},{"key":"2026110502150573000_51.11.1233.185","doi-asserted-by":"crossref","first-page":"1558","DOI":"10.1097\/00000542-199911000-00065","article-title":"Caution in performing epidural injections in patients on several antiplatelet drugs","volume":"91","author":"Benzon","year":"1999","journal-title":"Anesthesiology"},{"key":"2026110502150573000_51.11.1233.186","first-page":"526","article-title":"A case of epidural hematoma associated with epidural catheterization which occurred on 12th days after the last medication of ticlopidine hydrochloride","volume":"51","author":"Kawaguchi","year":"2002","journal-title":"Masui"},{"key":"2026110502150573000_51.11.1233.187","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1213\/00000539-198308000-00012","article-title":"Spinal subarachnoid hematoma after lumbar puncture in a patient receiving antiplatelet therapy","volume":"62","author":"Mayumi","year":"1983","journal-title":"Anesth Analg"},{"key":"2026110502150573000_51.11.1233.188","doi-asserted-by":"publisher","DOI":"10.1345\/aph.1D190"},{"key":"2026110502150573000_51.11.1233.189","doi-asserted-by":"publisher","DOI":"10.1046\/j.1468-0734.2001.00041.x"},{"key":"2026110502150573000_51.11.1233.190","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199711063371901"},{"key":"2026110502150573000_51.11.1233.191","doi-asserted-by":"crossref","DOI":"10.1177\/10742484221145010","article-title":"Fondaparinux Sodium: Recent Advances in the Management of Thrombosis","volume":"28","author":"Bauersachs","year":"2023","journal-title":"J Cardiovasc Pharmacol Ther"},{"key":"2026110502150573000_51.11.1233.192","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM200103013440901"},{"key":"2026110502150573000_51.11.1233.193","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM200107263450412"},{"key":"2026110502150573000_51.11.1233.194","doi-asserted-by":"publisher","DOI":"10.1213\/01.ane.0000287677.95626.60"},{"key":"2026110502150573000_51.11.1233.195","unstructured":"Brunton LL , Lazo JS , Parker KL . Goodman & Gilman\u2019s the pharmacological basis of therapeutics. New York: McGraw-Hill, 2006."},{"key":"2026110502150573000_51.11.1233.196","doi-asserted-by":"publisher","DOI":"10.1536\/jhj.43.417"},{"key":"2026110502150573000_51.11.1233.197","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1016\/S0736-4679(02)00546-2","article-title":"Spinal epidural hematoma complicating thrombolytic therapy with tissue plasminogen activator--a case report","volume":"23","author":"Clark","year":"2002","journal-title":"J Emerg Med"},{"key":"2026110502150573000_51.11.1233.198","doi-asserted-by":"crossref","first-page":"1694","DOI":"10.1097\/00007632-199607150-00016","article-title":"Management of Spinal Epidural Hematoma After Tissue Plasminogen Activator","volume":"21","author":"Connolly","year":"1996","journal-title":"Spine (Phila Pa 1986)"},{"key":"2026110502150573000_51.11.1233.199","first-page":"43","article-title":"Spinal epidural hematoma following coronary thrombolysis. A case report","volume":"48","author":"Cultrera","year":"2004","journal-title":"J Neurosurg Sci"},{"key":"2026110502150573000_51.11.1233.200","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1080\/10790268.2000.11753523","article-title":"Paraplegia subsequent to administration of tissue plasminogen activator and intravenous heparin following myocardial infarction--a case report","volume":"23","author":"DePorto","year":"2000","journal-title":"J Spinal Cord Med"},{"key":"2026110502150573000_51.11.1233.201","first-page":"688","article-title":"A rare complication of thrombolytic therapy: spinal epidural hematoma. A case report (Una rara complicanza della terapia trombolitica: l'ematoma spinale epidurale. Descrizione di un caso)","volume":"4","author":"Ferrante","year":"2003","journal-title":"Ital Heart J"},{"key":"2026110502150573000_51.11.1233.202","doi-asserted-by":"publisher","DOI":"10.1097\/00006123-199609000-00012"},{"key":"2026110502150573000_51.11.1233.203","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1136\/hrt.2004.043018","article-title":"Cervical extradural haematoma following thrombolysis","volume":"91","author":"Haldar","year":"2005","journal-title":"Heart"},{"key":"2026110502150573000_51.11.1233.204","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1007\/s00270-004-0133-2","article-title":"Spinal epidural hematoma after thrombolysis for deep vein thrombosis with subsequent pulmonary thromboembolism: a case report","volume":"29","author":"Han","year":"2006","journal-title":"Cardiovasc Intervent Radiol"},{"key":"2026110502150573000_51.11.1233.205","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1007\/s00296-007-0512-5","article-title":"Epidural hematoma mimicking transverse myelitis in a patient with primary antiphospholipid syndrome","volume":"28","author":"Kim","year":"2008","journal-title":"Rheumatol Int"},{"key":"2026110502150573000_51.11.1233.206","doi-asserted-by":"publisher","DOI":"10.1038\/sj.sc.3101604"},{"key":"2026110502150573000_51.11.1233.207","doi-asserted-by":"crossref","first-page":"350","DOI":"10.3171\/jns.1995.83.2.0350","article-title":"Spinal epidural hematoma following coronary thrombolysis with tissue plasminogen activator. Report of two cases","volume":"83","author":"Sawin","year":"1995","journal-title":"J Neurosurg"},{"key":"2026110502150573000_51.11.1233.208","doi-asserted-by":"publisher","DOI":"10.3346\/jkms.2005.20.2.331"},{"key":"2026110502150573000_51.11.1233.209","first-page":"287","article-title":"Acute cervical spinal epidural hematoma during antithrombotic therapy: dual warnings against antithrombotic therapy","volume":"43","author":"Toyonaga","year":"2003","journal-title":"Rinsho Shinkeigaku"},{"key":"2026110502150573000_51.11.1233.210","first-page":"236","article-title":"Spinal epidural hematoma - A rare and debilitating complication of thrombolytic therapy","volume":"4","author":"Gupta","year":"2013","journal-title":"J Cardiovasc Dis Res"},{"key":"2026110502150573000_51.11.1233.211","first-page":"390","article-title":"Spinal epidural hematoma associated with tissue plasminogen activator treatment of acute myocardial infarction","volume":"48","author":"Baron","year":"1999","journal-title":"Catheter Cardiovasc Interv Dec"},{"key":"2026110502150573000_51.11.1233.212","doi-asserted-by":"crossref","first-page":"947","DOI":"10.1097\/00000542-199005000-00028","article-title":"Spinal epidural hematoma associated with epidural anesthesia: complications of systemic heparinization in patients receiving peripheral vascular thrombolytic therapy","volume":"72","author":"Dickman","year":"1990","journal-title":"Anesthesiology"},{"key":"2026110502150573000_51.11.1233.213","first-page":"881","article-title":"Technical difficulties in epidural blocks and spinal bleeding complications","volume":"67","author":"Nava","year":"2001","journal-title":"Minerva Anestesiol"},{"key":"2026110502150573000_51.11.1233.214","doi-asserted-by":"crossref","first-page":"1221","DOI":"10.1097\/00000542-199212000-00025","article-title":"Epidural hematoma associated with epidural anesthesia: complications of anticoagulant therapy","volume":"77","author":"Onishchuk","year":"1992","journal-title":"Anesthesiology"},{"key":"2026110502150573000_51.11.1233.215","first-page":"409","article-title":"Intrathecal bleeding after the intraoperative use of heparin and urokinase during continuous spinal anesthesia","volume":"82","author":"Rabito","year":"1996","journal-title":"Anesth Analg"},{"key":"2026110502150573000_51.11.1233.216","doi-asserted-by":"publisher","DOI":"10.1378\/chest.08-0670"},{"key":"2026110502150573000_51.11.1233.217","doi-asserted-by":"crossref","first-page":"788","DOI":"10.1055\/s-0038-1646904","article-title":"The relative importance of the factors II, VII, IX and X for the prothrombinase activity in plasma of orally anticoagulated patients","volume":"62","author":"Xi","year":"1989","journal-title":"Thromb Haemost"},{"key":"2026110502150573000_51.11.1233.218","doi-asserted-by":"publisher","DOI":"10.4065\/76.3.260"},{"key":"2026110502150573000_51.11.1233.219","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1111\/j.1365-2044.1991.tb09707.x","article-title":"Lumbar regional anaesthesia and prophylactic anticoagulant therapy. Is the combination safe?","volume":"46","author":"Wille-J\u00f8rgensen","year":"1991","journal-title":"Anaesthesia"},{"key":"2026110502150573000_51.11.1233.220","doi-asserted-by":"publisher","DOI":"10.1177\/106002809502901214"},{"key":"2026110502150573000_51.11.1233.221","doi-asserted-by":"publisher","DOI":"10.1378\/chest.127.6.2049"},{"key":"2026110502150573000_51.11.1233.222","doi-asserted-by":"publisher","DOI":"10.1097\/AAP.0000000000000782"},{"key":"2026110502150573000_51.11.1233.223","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199106273242606"},{"key":"2026110502150573000_51.11.1233.224","doi-asserted-by":"crossref","first-page":"416","DOI":"10.2165\/00003088-199630060-00002","article-title":"Clinically important drug interactions with anticoagulants. An update","volume":"30","author":"Harder","year":"1996","journal-title":"Clin Pharmacokinet"},{"key":"2026110502150573000_51.11.1233.225","article-title":"Management of Life-Threatening Bleeding in Patients With Mechanical Heart Valves","volume":"13","author":"Huda","year":"2021","journal-title":"Cureus"},{"key":"2026110502150573000_51.11.1233.226","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1501035"},{"key":"2026110502150573000_51.11.1233.227","doi-asserted-by":"publisher","DOI":"10.1016\/j.wneu.2012.12.002"},{"key":"2026110502150573000_51.11.1233.228","doi-asserted-by":"publisher","DOI":"10.1097\/MBC.0b013e3282f185c9"},{"key":"2026110502150573000_51.11.1233.229","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1016\/j.thromres.2015.07.023","article-title":"Comparative effectiveness of 3- versus 4-factor prothrombin complex concentrate for emergent warfarin reversal","volume":"136","author":"Voils","year":"2015","journal-title":"Thromb Res"},{"key":"2026110502150573000_51.11.1233.230","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/j.jemermed.2015.07.024","article-title":"Evaluation of Warfarin Reversal with 4-Factor Prothrombin Complex Concentrate Compared to 3-Factor Prothrombin Complex Concentrate at a Tertiary Academic Medical Center","volume":"50","author":"Al-Majzoub","year":"2016","journal-title":"J Emerg Med"},{"key":"2026110502150573000_51.11.1233.231","doi-asserted-by":"publisher","DOI":"10.1097\/01.blo.0000246548.25811.2d"},{"key":"2026110502150573000_51.11.1233.232","doi-asserted-by":"publisher","DOI":"10.1097\/AAP.0b013e31820d4376"},{"key":"2026110502150573000_51.11.1233.233","doi-asserted-by":"publisher","DOI":"10.1097\/ALN.0b013e3181ca6cfc"},{"key":"2026110502150573000_51.11.1233.234","unstructured":"Warfarin dosing. Available: www.WarfarinDosing.org [Accessed 1 May 2023]."},{"key":"2026110502150573000_51.11.1233.235","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-127-1-199707010-00010"},{"key":"2026110502150573000_51.11.1233.236","doi-asserted-by":"publisher","DOI":"10.1001\/archfami.1997.01850490091023"},{"key":"2026110502150573000_51.11.1233.237","doi-asserted-by":"publisher","DOI":"10.4065\/74.5.443"},{"key":"2026110502150573000_51.11.1233.238","doi-asserted-by":"publisher","DOI":"10.1097\/00006123-199005000-00026"},{"key":"2026110502150573000_51.11.1233.239","doi-asserted-by":"crossref","DOI":"10.1212\/WNL.48.4.1137","article-title":"Ginkgo biloba","volume":"48","author":"Gilbert","year":"1997","journal-title":"Neurology (ECronicon)"},{"key":"2026110502150573000_51.11.1233.240","doi-asserted-by":"crossref","first-page":"1933","DOI":"10.1212\/WNL.50.6.1933","article-title":"Association of Ginkgo biloba with intracerebral hemorrhage","volume":"50","author":"Matthews","year":"1998","journal-title":"Neurology (ECronicon)"},{"key":"2026110502150573000_51.11.1233.241","doi-asserted-by":"crossref","first-page":"1775","DOI":"10.1212\/WNL.46.6.1775","article-title":"Spontaneous bilateral subdural hematomas associated with chronic Ginkgo biloba ingestion","volume":"46","author":"Rowin","year":"1996","journal-title":"Neurology (ECronicon)"},{"key":"2026110502150573000_51.11.1233.242","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/S0140-6736(05)79516-7","article-title":"Subarachnoid haemorrhage associated with Ginkgo biloba","volume":"352","author":"Vale","year":"1998","journal-title":"Lancet"},{"key":"2026110502150573000_51.11.1233.243","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-200609000-00007"},{"key":"2026110502150573000_51.11.1233.244","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1097\/00000542-200609000-00002","article-title":"Herbal medicines and perioperative care","volume":"105","author":"Moss","year":"2006","journal-title":"Anesthesiology"},{"key":"2026110502150573000_51.11.1233.245","doi-asserted-by":"publisher","DOI":"10.1016\/S2214-109X(14)70227-X"},{"key":"2026110502150573000_51.11.1233.246","doi-asserted-by":"crossref","first-page":"942","DOI":"10.1213\/ANE.0000000000001569","article-title":"National Partnership for Maternal Safety: Consensus Bundle on Venous Thromboembolism","volume":"123","author":"D\u2019Alton","year":"2016","journal-title":"Anesth Analg"},{"key":"2026110502150573000_51.11.1233.247","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0000000000002706"},{"key":"2026110502150573000_51.11.1233.248","doi-asserted-by":"crossref","first-page":"572","DOI":"10.1016\/j.chest.2016.05.021","article-title":"Risks of Venous Thromboembolism After Cesarean Sections: A Meta-Analysis","volume":"150","author":"Blondon","year":"2016","journal-title":"Chest"},{"key":"2026110502150573000_51.11.1233.249","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-143-10-200511150-00006"},{"key":"2026110502150573000_51.11.1233.250","doi-asserted-by":"crossref","first-page":"1454","DOI":"10.1055\/s-0040-1714211","article-title":"Clinical Characteristics and Outcomes of Women Presenting with Venous Thromboembolism during Pregnancy and Postpartum Period: Findings from the RIETE Registry","volume":"120","author":"Elgendy","year":"2020","journal-title":"Thromb Haemost"},{"key":"2026110502150573000_51.11.1233.251","doi-asserted-by":"publisher","DOI":"10.1016\/S1521-6926(03)00021-5"},{"key":"2026110502150573000_51.11.1233.252","doi-asserted-by":"crossref","first-page":"786","DOI":"10.1213\/ANE.0000000000001143","article-title":"Pharmacokinetics and Pharmacodynamics of Drugs Commonly Used in Pregnancy and Parturition","volume":"122","author":"Ansari","year":"2016","journal-title":"Anesth Analg"},{"key":"2026110502150573000_51.11.1233.253","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(95)91362-9"},{"key":"2026110502150573000_51.11.1233.254","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1055\/s-0037-1612949","article-title":"The APTT response of pregnant plasma to unfractionated heparin","volume":"87","author":"Chunilal","year":"2002","journal-title":"Thromb Haemost"},{"key":"2026110502150573000_51.11.1233.255","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(99)70091-8"},{"key":"2026110502150573000_51.11.1233.256","doi-asserted-by":"publisher","DOI":"10.1038\/clpt.2008.73"},{"key":"2026110502150573000_51.11.1233.257","doi-asserted-by":"publisher","DOI":"10.1213\/ANE.0b013e318251daed"},{"key":"2026110502150573000_51.11.1233.258","doi-asserted-by":"publisher","DOI":"10.1016\/S0959-289X(98)80021-6"},{"key":"2026110502150573000_51.11.1233.259","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1213\/ANE.0000000000002173","article-title":"Neuraxial Anesthesia in Obstetric Patients Receiving Thromboprophylaxis With Unfractionated or Low-Molecular-Weight Heparin: A Systematic Review of Spinal Epidural Hematoma","volume":"125","author":"Leffert","year":"2017","journal-title":"Anesth Analg"},{"key":"2026110502150573000_51.11.1233.260","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1016\/j.ijoa.2018.09.008","article-title":"Epidural hematoma following low molecular weight heparin prophylaxis and spinal anesthesia for cesarean delivery","volume":"37","author":"Pujic","year":"2019","journal-title":"Int J Obstet Anesth"},{"key":"2026110502150573000_51.11.1233.261","doi-asserted-by":"crossref","first-page":"912","DOI":"10.1097\/ALN.0000000000002629","article-title":"Adverse Events and Factors Associated with Potentially Avoidable Use of General Anesthesia in Cesarean Deliveries","volume":"130","author":"Guglielminotti","year":"2019","journal-title":"Anesthesiology"},{"key":"2026110502150573000_51.11.1233.262","unstructured":"The American College of Obstetricians and Gynecologists . Inherited Thrombophilias in Pregnancy. Pract Bull 2018;197."},{"key":"2026110502150573000_51.11.1233.263","doi-asserted-by":"publisher","DOI":"10.1213\/ANE.0b013e3181cf03b4"},{"key":"2026110502150573000_51.11.1233.264","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1111\/j.1365-2044.2011.06971.x","article-title":"Large retroperitoneal haematoma: an unexpected complication of ilioinguinal nerve block for inguinal hernia repair","volume":"67","author":"Parvaiz","year":"2012","journal-title":"Anaesthesia"},{"key":"2026110502150573000_51.11.1233.265","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1016\/j.jclinane.2010.03.009","article-title":"Intraneural hematoma after nerve stimulation-guided femoral block in a patient with factor XI deficiency: case report","volume":"23","author":"Rodr\u00edguez","year":"2011","journal-title":"J Clin Anesth"},{"key":"2026110502150573000_51.11.1233.266","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1213\/XAA.0000000000000261","article-title":"Acute Retroperitoneal Hematoma After Psoas Catheter Placement in a Patient with Myeloproliferative Thrombocytosis and Aspirin Therapy","volume":"6","author":"Warner","year":"2016","journal-title":"A A Case Rep"},{"key":"2026110502150573000_51.11.1233.267","doi-asserted-by":"publisher","DOI":"10.1097\/AAP.0000000000000127"},{"key":"2026110502150573000_51.11.1233.268","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1097\/00115550-199924030-00016","article-title":"Axillary block complicated by hematoma and radial nerve injury","volume":"24","author":"Ben-David","year":"1999","journal-title":"Reg Anesth Pain Med"},{"key":"2026110502150573000_51.11.1233.269","doi-asserted-by":"publisher","DOI":"10.1097\/00000539-200301000-00050"},{"key":"2026110502150573000_51.11.1233.270","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1046\/j.1460-9592.2003.01005.x","article-title":"Is ilioinguinal\/iliohypogastric nerve block always totally safe in children?","volume":"13","author":"Amory","year":"2003","journal-title":"Pediatr Anesth"},{"key":"2026110502150573000_51.11.1233.271","doi-asserted-by":"publisher","DOI":"10.1111\/j.1460-9592.2006.01909.x"},{"key":"2026110502150573000_51.11.1233.272","doi-asserted-by":"crossref","first-page":"1048","DOI":"10.1097\/00000539-200104000-00045","article-title":"Pelvic hematoma after an ilioinguinal nerve block for orchialgia","volume":"92","author":"Vaisman","year":"2001","journal-title":"Anesth Analg"},{"key":"2026110502150573000_51.11.1233.273","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-200109000-00040"},{"key":"2026110502150573000_51.11.1233.274","doi-asserted-by":"publisher","DOI":"10.1097\/00000539-200108000-00040"},{"key":"2026110502150573000_51.11.1233.275","doi-asserted-by":"publisher","DOI":"10.1016\/0090-4295(84)90212-7"},{"key":"2026110502150573000_51.11.1233.276","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/83.4.668"},{"key":"2026110502150573000_51.11.1233.277","first-page":"523","article-title":"Retroperitoneal hematoma as a complication of pudendal block. Diagnosis made by computed tomography","volume":"164","author":"Kurzel","year":"1996","journal-title":"West J Med"},{"key":"2026110502150573000_51.11.1233.278","doi-asserted-by":"publisher","DOI":"10.1136\/rapm-00115550-199823050-00016"},{"key":"2026110502150573000_51.11.1233.279","doi-asserted-by":"crossref","first-page":"410","DOI":"10.4103\/0259-1162.143170","article-title":"Massive hemothorax: A rare complication after supraclavicular brachial plexus block","volume":"8","author":"Singh","year":"2014","journal-title":"Anesth Essays Res"},{"key":"2026110502150573000_51.11.1233.280","doi-asserted-by":"publisher","DOI":"10.1097\/EJA.0b013e32833f6f6f"},{"key":"2026110502150573000_51.11.1233.281","doi-asserted-by":"crossref","DOI":"10.1097\/00000542-199907000-00061","article-title":"Epidural catheter removal before unanticipated anticoagulation: the pharmacy fail-safe","volume":"91","author":"Keegan","year":"1999","journal-title":"Anesthesiology"},{"key":"2026110502150573000_51.11.1233.282","doi-asserted-by":"crossref","first-page":"1356","DOI":"10.1007\/s12630-019-01466-w","article-title":"Practice advisory on the bleeding risks for peripheral nerve and interfascial plane blockade: evidence review and expert consensus","volume":"66","author":"Tsui","year":"2019","journal-title":"Can J Anaesth"},{"key":"2026110502150573000_51.11.1233.283","doi-asserted-by":"crossref","unstructured":"Benzon HT , Nelson AM , Patel AG , et al . Literature review of spinal hematoma case reports: causes and outcomes in pediatric, obstetric, neuraxial and pain medicine cases. Reg Anesth Pain Med 2024. doi:10.1136\/rapm-2023-105161","DOI":"10.1136\/rapm-2023-105161"},{"key":"2026110502150573000_51.11.1233.284","doi-asserted-by":"crossref","first-page":"e207","DOI":"10.1016\/j.chest.2022.07.025","article-title":"Perioperative Management of Antithrombotic Therapy: An American College of Chest Physicians Clinical Practice Guideline","volume":"162","author":"Douketis","year":"2022","journal-title":"Chest"},{"key":"2026110502150573000_51.11.1233.285","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2013.11.006"},{"key":"2026110502150573000_51.11.1233.286","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1160\/TH08-07-0460","article-title":"A randomized evaluation of betrixaban, an oral factor Xa inhibitor, for prevention of thromboembolic events after total knee replacement (EXPERT)","volume":"101","author":"Turpie","year":"2009","journal-title":"Thromb Haemost"},{"key":"2026110502150573000_51.11.1233.287","unstructured":"Bevyxxa full prescribing information. Portola. Available: https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2017\/208383s000lbl.pdf [Accessed 13 Mar 2024]."},{"key":"2026110502150573000_51.11.1233.288","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1002\/jcph.633","article-title":"Effect of renal impairment on the pharmacokinetics, pharmacodynamics, and safety of apixaban","volume":"56","author":"Chang","year":"2016","journal-title":"J Clin Pharma"},{"key":"2026110502150573000_51.11.1233.289","unstructured":"Savaysa: full prescribing information. Available: http:\/\/dsi.com\/prescribing-information-portlet\/getPIContent?productName=Savaysa&inline=true [Accessed 14 Mar 2022]."},{"key":"2026110502150573000_51.11.1233.290","first-page":"1091","article-title":"Effect of renal function on edoxaban pharmacokinetics (pk) and on population pk\/pk-pd model","volume":"49","author":"Ridout","year":"2009","journal-title":"J Clin Pharmacol"},{"key":"2026110502150573000_51.11.1233.291","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1111\/j.1365-2125.2010.03753.x","article-title":"Effects of renal impairment on the pharmacokinetics, pharmacodynamics and safety of rivaroxaban, an oral, direct Factor Xa inhibitor","volume":"70","author":"Kubitza","year":"2010","journal-title":"Brit J Clinical Pharma"},{"key":"2026110502150573000_51.11.1233.292","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1159\/000445328","article-title":"Pharmacokinetics, Pharmacodynamics, and Safety of Single-Dose Rivaroxaban in Chronic Hemodialysis","volume":"43","author":"Dias","year":"2016","journal-title":"Am J Nephrol"},{"key":"2026110502150573000_51.11.1233.293","doi-asserted-by":"publisher","DOI":"10.2165\/00003088-200847010-00005"},{"key":"2026110502150573000_51.11.1233.294","doi-asserted-by":"publisher","DOI":"10.2165\/11318170-000000000-00000"},{"key":"2026110502150573000_51.11.1233.295","doi-asserted-by":"crossref","first-page":"1013","DOI":"10.1097\/ALN.0000000000000846","article-title":"Temporal Trends in Anesthesia-related Adverse Events in Cesarean Deliveries, New York State, 2003\u20132012","volume":"123","author":"Guglielminotti","year":"2015","journal-title":"Anesthesiology"},{"key":"2026110502150573000_51.11.1233.296","doi-asserted-by":"publisher","DOI":"10.1097\/ALN.0000000000000253"},{"key":"2026110502150573000_51.11.1233.297","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijoa.2015.06.008"},{"key":"2026110502150573000_51.11.1233.298","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1186\/s12884-016-0959-z","article-title":"Examining the impact of introducing ICD-MM on observed trends in maternal mortality rates in the UK 2003\u201313","volume":"16","author":"Knight","year":"2016","journal-title":"BMC Pregnancy Childbirth"},{"key":"2026110502150573000_51.11.1233.299","doi-asserted-by":"publisher","DOI":"10.1111\/anae.12826"},{"key":"2026110502150573000_51.11.1233.300","doi-asserted-by":"crossref","first-page":"462","DOI":"10.1016\/j.ajog.2011.06.068","article-title":"Anesthetic management as a risk factor for postpartum hemorrhage after cesarean deliveries","volume":"205","author":"Chang","year":"2011","journal-title":"Am J Obstet Gynecol"},{"key":"2026110502150573000_51.11.1233.301","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-200309000-00010"},{"key":"2026110502150573000_51.11.1233.302","first-page":"672","article-title":"Comparison of general and regional anesthesia for cesarean section: success rate, blood loss and satisfaction from a randomized trial","volume":"82","author":"Lertakyamanee","year":"1999","journal-title":"J Med Assoc Thai"},{"key":"2026110502150573000_51.11.1233.303","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/aer262"},{"key":"2026110502150573000_51.11.1233.304","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/j.ijoa.2013.01.008","article-title":"Chronic pain after childbirth","volume":"22","author":"Landau","year":"2013","journal-title":"Int J Obstet Anesth"},{"key":"2026110502150573000_51.11.1233.305","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-6576.2004.00271.x"},{"key":"2026110502150573000_51.11.1233.306","article-title":"Early skin-to-skin contact for mothers and their healthy newborn infants","volume":"5","author":"Moore","year":"2012","journal-title":"Cochrane Database Syst Rev"},{"key":"2026110502150573000_51.11.1233.307","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2008.01777.x"},{"key":"2026110502150573000_51.11.1233.308","doi-asserted-by":"publisher","DOI":"10.1186\/1741-7015-7-20"},{"key":"2026110502150573000_51.11.1233.309","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1111\/j.1479-828X.2012.01457.x","article-title":"Mode of anaesthetic for category 1 caesarean sections and neonatal outcomes","volume":"52","author":"Beckmann","year":"2012","journal-title":"Aust NZ J Obst Gynaeco"},{"key":"2026110502150573000_51.11.1233.310","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijoa.2012.01.005"}],"container-title":["Regional Anesthesia & Pain Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/rapm-2024-105766","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,11,5]],"date-time":"2026-11-05T10:16:25Z","timestamp":1793873785000},"score":1,"resource":{"primary":{"URL":"https:\/\/rapm.bmj.com\/lookup\/doi\/10.1136\/rapm-2024-105766"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1,29]]},"references-count":310,"journal-issue":{"issue":"11","published-online":{"date-parts":[[2026,11,5]]},"published-print":{"date-parts":[[2026,11]]}},"alternative-id":["10.1136\/rapm-2024-105766"],"URL":"https:\/\/doi.org\/10.1136\/rapm-2024-105766","relation":{"has-part":[{"id-type":"doi","id":"https:\/\/doi.org\/10.1136\/rapm-2024-105766.supp1","asserted-by":"subject"}]},"ISSN":["1098-7339","1532-8651"],"issn-type":[{"value":"1098-7339","type":"print"},{"value":"1532-8651","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,1,29]]}}}