{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,3]],"date-time":"2026-11-03T12:12:38Z","timestamp":1793707958820,"version":"4.6.1"},"reference-count":33,"publisher":"BMJ","issue":"1","funder":[{"DOI":"10.13039\/100019016","name":"Assessment of Spondyloarthritis International Society","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100019016","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["RMD Open"],"accepted":{"date-parts":[[2019,4,29]]},"published-print":{"date-parts":[[2019,5]]},"abstract":"<jats:sec>\n                  <jats:title>Objective<\/jats:title>\n                  <jats:p>Health utilities represent preference values that persons attach to health states. This study aims to develop one general and six country-specific algorithms to calculate societal preference values for health of patients with spondyloarthritis (SpA), as assessed by the disease-specific Assessment of SpondyloArthritis international Society Health Index (ASAS HI).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>A survey was performed in random population samples from six European countries. In a best-worst choice experiment, subjects were asked to indicate repeatedly which of 4 random aspects of the 17-item ASAS HI was were most and least important. Bayesian analysis provided the relative importance of each of the 17 items. To rescale the relative importance scores on the absolute utility scale between 0 and 1, participants additionally completed two lead time trade-off experiments, one for \u2018severe SpA\u2019 and one for \u2018best health\u2019 without SpA. Six country-specific algorithms and one general algorithm were derived. The general algorithm was tested in 199 patients with axial SpA (axSpA).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>3039 subjects, mean age 47 years (SD 15) and 52% female completed the experiments. The population\u2019s health utility value for SpA varied between \u2212 0.24 for \u2018worst\u2019 SpA (country range \u22120.35 to 0.03), and 0.88 for \u2018best\u2019 health (country range 0.81 to 0.90). Among 199 patients with axSpA, the mean utility was 0.36 (SD 0.30, range \u22120.24 to 0.88) and discriminated well between patients having high (Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) \u2265 4) or low (BASDAI &lt; 4) disease activity (0.18 (SD 0.24) vs 0.51(SD 0.27), p&lt;0.01).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>One general and six country-specific algorithms are available to convert scores from the ASAS HI into disease-specific societal utility values.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1136\/rmdopen-2018-000872","type":"journal-article","created":{"date-parts":[[2019,5,22]],"date-time":"2019-05-22T07:18:30Z","timestamp":1558509510000},"page":"e000872","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":12,"title":["Development of one general and six country-specific algorithms to assess societal health utilities based on ASAS HI"],"prefix":"10.1136","volume":"5","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9750-4429","authenticated-orcid":false,"given":"Ivette","family":"Essers","sequence":"first","affiliation":[{"name":"Rheumatology, Maastricht University Medical Center, Maastricht, Limburg, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mickael","family":"Hiligsmann","sequence":"additional","affiliation":[{"name":"Department of Health Services Research, Maastricht University, Maastricht, Limburg, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Uta","family":"Kiltz","sequence":"additional","affiliation":[{"name":"Rheumazentrum Ruhrgebiet, Ruhr-University Bochum, Herne, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nick","family":"Bansback","sequence":"additional","affiliation":[{"name":"School of Population and Public Health, University of British Columbia, Vancouver, British Columbia, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juergen","family":"Braun","sequence":"additional","affiliation":[{"name":"Rheumazentrum Ruhrgebiet, Herne, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5781-158X","authenticated-orcid":false,"given":"Desir\u00e9e","family":"van der Heijde","sequence":"additional","affiliation":[{"name":"Rheumatology, LUMC, Leiden, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annelies","family":"Boonen","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Division of Rheumatology, Maastricht University Medical Center, and the Caphri Research Institute Maastricht University, Maastricht, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2019,5,21]]},"reference":[{"key":"2025090312045154000_5.1.e000872.1","first-page":"978","article-title":"Update of the ASAS-EULAR management recommendations for axial spondyloarthritis","volume":"2017","author":"van der Heijde, Ramiro","year":"2016","journal-title":"Ann Rheum Dis"},{"key":"2025090312045154000_5.1.e000872.2","doi-asserted-by":"publisher","DOI":"10.1136\/ard.62.1.20"},{"key":"2025090312045154000_5.1.e000872.3","first-page":"S- 105","article-title":"The ASAS Health Index (ASAS HI) - a new tool to assess the health status of patients with spondyloarthritis","volume":"32","author":"Kiltz","year":"2014","journal-title":"Clin Exp Rheumatol"},{"key":"2025090312045154000_5.1.e000872.4","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1097\/SLA.0b013e31818a43af","article-title":"Value-based health care delivery","volume":"248","author":"Porter","year":"2008","journal-title":"Ann Surg"},{"key":"2025090312045154000_5.1.e000872.5","unstructured":"Neumann V . 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