{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T17:25:23Z","timestamp":1757611523787,"version":"3.44.0"},"reference-count":28,"publisher":"BMJ","issue":"1","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["RMD Open"],"accepted":{"date-parts":[[2019,3,29]]},"published-print":{"date-parts":[[2019,4]]},"abstract":"<jats:sec>\n                  <jats:title>Objectives<\/jats:title>\n                  <jats:p>To validate cut-offs of the Juvenile Arthritis Disease Activity Score 10 (JADAS10) and clinical JADAS10 (cJADAS10) and to compare them with other patient cohorts.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>In a national multicentre study, cross-sectional data on recent visits of 337 non-systemic patients with juvenile idiopathic arthritis (JIA) were collected from nine paediatric outpatient units. The cut-offs were tested with receiver operating characteristic curve-based methods, and too high, too low and correct classification rates (CCRs) were calculated.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Our earlier presented JADAS10 cut-offs seemed feasible based on the CCRs, but the cut-off values between low disease activity (LDA) and moderate disease activity (MDA) were adjusted. When JADAS10 cut-offs for clinically inactive disease (CID) were increased to 1.5 for patients with oligoarticular disease and 2.7 for patients with polyarticular disease, as recently suggested in a large multinational register study, altogether 11 patients classified as CID by the cut-off had one active joint. We suggest JADAS10 cut-off values for oligoarticular\/polyarticular disease to be in CID: 0.0\u20130.5\/0.0\u20130.7, LDA: 0.6\u20133.8\/0.8\u20135.1 and MDA: &gt;3.8\/5.1. Suitable cJADAS10 cut-offs are the same as JADAS10 cut-offs in oligoarticular disease. In polyarticular disease, cJADAS10 cut-offs are 0\u20130.7 for CID, 0.8\u20135.0 for LDA and &gt;5.0 for MDA.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>International consensus on JADAS cut-off values is needed, and such a cut-off for CID should preferably exclude patients with active joints in the CID group.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1136\/rmdopen-2018-000888","type":"journal-article","created":{"date-parts":[[2019,4,25]],"date-time":"2019-04-25T06:00:37Z","timestamp":1556172037000},"page":"e000888","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":13,"title":["Validating 10-joint juvenile arthritis disease activity score cut-offs for disease activity levels in non-systemic juvenile idiopathic arthritis"],"prefix":"10.1136","volume":"5","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8632-8634","authenticated-orcid":false,"given":"Maria","family":"Backstr\u00f6m","sequence":"first","affiliation":[{"name":"Pediatric Department, Vaasan keskussairaala, Vaasa, Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pirjo","family":"Tynj\u00e4l\u00e4","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, South Karelia Central Hospital, Lappeenranta, Finland"},{"name":"Poison Information Center, University of Helsinki Hospital, Helsinki, Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kristiina","family":"Aalto","sequence":"additional","affiliation":[{"name":"Hospital for Children and Adolescents, University of Helsinki Hospital for Children and Adolescents, Helsinki, Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Minna-Maija","family":"Gr\u00f6nlund","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Turku University Hospital, Turku, Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Heikki","family":"Ylijoki","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Satakunta Central Hospital, Pori, Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anne","family":"Putto-Laurila","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Turku University Hospital, Turku, Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Johanna","family":"K\u00e4rki","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Kanta-H\u00e4me Central Hospital, H\u00e4meenlinna, Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paula","family":"Keskitalo","sequence":"additional","affiliation":[{"name":"Department of Paediatrics, Oulu University Hospital, Oulu, Finland"},{"name":"Medical Research Center Oulu, Oulu University Hospital and PEDEGO Research Unit, University of Oulu, Oulu, Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sirja","family":"Sard","sequence":"additional","affiliation":[{"name":"Department of Paediatrics, Oulu University Hospital, Oulu, Finland"},{"name":"Medical Research Center Oulu, Oulu University Hospital and PEDEGO Research Unit, University of Oulu, Oulu, Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Heini","family":"Pohjankoski","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, P\u00e4ij\u00e4t-H\u00e4me Central Hospital, Lahti, Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maiju","family":"Hietanen","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, P\u00e4ij\u00e4t-H\u00e4me Central Hospital, Lahti, Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Silke","family":"Witter","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Central Finland Hospital District, Jyvaskyla, Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Helena","family":"Lehto","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, South Karelia Central Hospital, Lappeenranta, Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eliisa","family":"L\u00f6yttyniemi","sequence":"additional","affiliation":[{"name":"Department of Biostatistics, University of Turku, Turku, Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2712-3903","authenticated-orcid":false,"given":"Paula","family":"V\u00e4h\u00e4salo","sequence":"additional","affiliation":[{"name":"Department of Paediatrics, Oulu University Hospital, Oulu, Finland"},{"name":"Medical Research Center Oulu, Oulu University Hospital and PEDEGO Research Unit, University of Oulu, Oulu, Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2019,4,24]]},"reference":[{"key":"2025090313324463000_5.1.e000888.1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rdc.2012.04.006"},{"key":"2025090313324463000_5.1.e000888.2","doi-asserted-by":"publisher","DOI":"10.1002\/art.34343"},{"key":"2025090313324463000_5.1.e000888.3","doi-asserted-by":"publisher","DOI":"10.1136\/ard.2010.143347"},{"key":"2025090313324463000_5.1.e000888.4","first-page":"41","article-title":"Time to treatment is an important factor 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Pediatric Rheumatol 2017;15(Suppl 2)."},{"key":"2025090313324463000_5.1.e000888.20","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/kev353"},{"key":"2025090313324463000_5.1.e000888.21","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(1950)3:1<32::AID-CNCR2820030106>3.0.CO;2-3"},{"key":"2025090313324463000_5.1.e000888.22","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2016-210511"},{"key":"2025090313324463000_5.1.e000888.23","doi-asserted-by":"crossref","first-page":"1519","DOI":"10.1002\/art.40519","article-title":"Long-term outcomes following achievement of clinically inactive disease in juvenile idiopathic arthritis: the importance of definition","volume":"70","author":"Shoop-Worrall","year":"2018","journal-title":"Arthritis Rheumatol"},{"key":"2025090313324463000_5.1.e000888.24","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1002\/acr.23203","article-title":"Lack of concordance in interrater scoring of the provider's global assessment of children with juvenile idiopathic arthritis with low disease activity","volume":"70","author":"Taylor","year":"2018","journal-title":"Arthritis Care Res"},{"key":"2025090313324463000_5.1.e000888.25","doi-asserted-by":"publisher","DOI":"10.1016\/j.eurpsy.2004.12.014"},{"key":"2025090313324463000_5.1.e000888.26","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2017-212104"},{"key":"2025090313324463000_5.1.e000888.27","doi-asserted-by":"crossref","first-page":"1096","DOI":"10.1097\/AJP.0000000000000639","article-title":"Risk and resilience in pediatric pain: the roles of parent and adolescent Catastrophizing and acceptance","volume":"34","author":"Feinstein","year":"2018","journal-title":"Clin J Pain"},{"key":"2025090313324463000_5.1.e000888.28","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1016\/S0304-3959(03)00076-9","article-title":"Keefe J Levefrebve JC, Romano JM, Turner JA. One- and two-item measures of pain beliefs and coping strategies","volume":"104","author":"Jensen","year":"2003","journal-title":"Pain"}],"container-title":["RMD Open"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/rmdopen-2018-000888","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,3]],"date-time":"2025-09-03T20:32:56Z","timestamp":1756931576000},"score":1,"resource":{"primary":{"URL":"https:\/\/rmdopen.bmj.com\/lookup\/doi\/10.1136\/rmdopen-2018-000888"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,4]]},"references-count":28,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2019,4,24]]},"published-print":{"date-parts":[[2019,4]]}},"alternative-id":["10.1136\/rmdopen-2018-000888"],"URL":"https:\/\/doi.org\/10.1136\/rmdopen-2018-000888","relation":{},"ISSN":["2056-5933"],"issn-type":[{"type":"electronic","value":"2056-5933"}],"subject":[],"published":{"date-parts":[[2019,4]]}}}