{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,15]],"date-time":"2026-04-15T00:59:08Z","timestamp":1776214748899,"version":"3.50.1"},"reference-count":16,"publisher":"BMJ","issue":"3","license":[{"start":{"date-parts":[[2021,12,3]],"date-time":"2021-12-03T00:00:00Z","timestamp":1638489600000},"content-version":"unspecified","delay-in-days":2,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["RMD Open"],"accepted":{"date-parts":[[2021,11,16]]},"published-print":{"date-parts":[[2021,12]]},"abstract":"<jats:sec>\n                  <jats:title>Objectives<\/jats:title>\n                  <jats:p>This study aims to provide a comprehensive analysis of the age-dependent risk of psoriatic arthritis (PsA). For this purpose, it focuses on the varying incidences within the different age groups.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>The data were collected as part of the morbidity-based risk adjustment of the statutory health insurance companies in Germany. This survey recorded the International Statistical Classification of Diseases and Related Health Problems (ICD)-coded diagnoses of 65 million German citizens. Our population-based study used these raw data to calculate the prevalence of PsA in the first step. Subsequently, we employed a new approach for the estimation of the age-specific and sex-specific incidence of PsA.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>The age-specific and sex-specific incidence of PsA showed a continuous increase with rising age until it peaked slightly before the age of 60 and declined thereafter. The maximum value was higher in women (40 per 100 000 py) than in men (30 per 100 000 py). Furthermore, the incidence rate tends to climb over the survey period.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>The data sets identified an unexpected high incidence. A meta-analysis by Scotti <jats:italic>et al<\/jats:italic> and other recent population-based studies served as a reference for the comparison. The pattern of the age-specific incidence illustrated that the risk for PsA disease shows considerable variations depending on age.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1136\/rmdopen-2021-001975","type":"journal-article","created":{"date-parts":[[2021,12,3]],"date-time":"2021-12-03T11:56:36Z","timestamp":1638532596000},"page":"e001975","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":20,"title":["Risk of psoriatic arthritis depending on age: analysis of data from 65 million people on statutory insurance in Germany"],"prefix":"10.1136","volume":"7","author":[{"given":"Madeline","family":"Deike","sequence":"first","affiliation":[{"name":"Department and Hiller-Research-Unit for Rheumatology, Heinrich Heine University D\u00fcsseldorf, Dusseldorf, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ralph","family":"Brinks","sequence":"additional","affiliation":[{"name":"Department and Hiller-Research-Unit for Rheumatology, Heinrich Heine University D\u00fcsseldorf, Dusseldorf, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephan","family":"Meller","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Heinrich-Heine-Universitat Dusseldorf, Dusseldorf, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthias","family":"Schneider","sequence":"additional","affiliation":[{"name":"Department and Hiller-Research-Unit for Rheumatology, Heinrich Heine University D\u00fcsseldorf, Dusseldorf, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8465-6207","authenticated-orcid":false,"given":"Philipp","family":"Sewerin","sequence":"additional","affiliation":[{"name":"Department and Hiller-Research-Unit for Rheumatology, Heinrich Heine University D\u00fcsseldorf, Dusseldorf, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2021,12,3]]},"reference":[{"key":"2025090313255782000_7.3.e001975.1","doi-asserted-by":"publisher","DOI":"10.3109\/09546634.2015.1044492"},{"key":"2025090313255782000_7.3.e001975.2","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1016\/j.semarthrit.2018.01.003","article-title":"Prevalence and incidence of psoriatic arthritis: a systematic review and meta-analysis","volume":"48","author":"Scotti","year":"2018","journal-title":"Semin Arthritis Rheum"},{"key":"2025090313255782000_7.3.e001975.3","doi-asserted-by":"crossref","first-page":"1878","DOI":"10.1002\/art.41741","article-title":"The epidemiology of psoriatic arthritis over five decades: a population-based study","volume":"73","author":"Karmacharya","year":"2021","journal-title":"Arthritis Rheumatol"},{"key":"2025090313255782000_7.3.e001975.4","doi-asserted-by":"crossref","first-page":"1243","DOI":"10.1093\/rheumatology\/keaa448","article-title":"Epidemiologic study of patients with psoriatic arthritis in a real-world analysis: a cohort study of the French health insurance database","volume":"60","author":"Pina Vegas","year":"2021","journal-title":"Rheumatology"},{"key":"2025090313255782000_7.3.e001975.5","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1016\/j.jhealeco.2017.03.001","article-title":"Plan responses to Diagnosis-based payment: evidence from Germany's morbidity-based risk adjustment","volume":"56","author":"Bauhoff","year":"2017","journal-title":"J Health Econ"},{"key":"2025090313255782000_7.3.e001975.6","doi-asserted-by":"crossref","first-page":"2070","DOI":"10.1002\/sim.5651","article-title":"Deriving age-specific incidence from prevalence with an ordinary differential equation","volume":"32","author":"Brinks","year":"2013","journal-title":"Stat Med"},{"key":"2025090313255782000_7.3.e001975.7","doi-asserted-by":"crossref","first-page":"dqu024","DOI":"10.1093\/imammb\/dqu024","article-title":"A new relation between prevalence and incidence of a chronic disease","volume":"32","author":"Brinks","year":"2015","journal-title":"Math Med Biol"},{"key":"2025090313255782000_7.3.e001975.8","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2796.2010.02310.x"},{"key":"2025090313255782000_7.3.e001975.9","doi-asserted-by":"crossref","DOI":"10.12688\/f1000research.19144.1","article-title":"Psoriatic arthritis","volume":"8","author":"Ocampo D","year":"2019","journal-title":"F1000Res"},{"key":"2025090313255782000_7.3.e001975.10","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2018-214065"},{"key":"2025090313255782000_7.3.e001975.11","doi-asserted-by":"crossref","first-page":"1084","DOI":"10.1002\/acr.23743","article-title":"Trends in the prevalence and incidence of psoriasis and psoriatic arthritis in Ontario, Canada: a population-based study","volume":"71","author":"Eder","year":"2019","journal-title":"Arthritis Care Res"},{"key":"2025090313255782000_7.3.e001975.12","doi-asserted-by":"publisher","DOI":"10.3899\/jrheum.080691"},{"key":"2025090313255782000_7.3.e001975.13","doi-asserted-by":"crossref","DOI":"10.12688\/f1000research.28023.1","article-title":"Impact of diagnostic accuracy on the estimation of excess mortality from incidence and prevalence: simulation study and application to diabetes in German men","volume":"10","author":"Brinks","year":"2021","journal-title":"F1000Res"},{"key":"2025090313255782000_7.3.e001975.14","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0152046","article-title":"Surveillance of the incidence of non-communicable diseases (NCDS) with sparse resources: a simulation study using data from a national diabetes registry, Denmark, 1995-2004","volume":"11","author":"Brinks","year":"2016","journal-title":"PLoS One"},{"key":"2025090313255782000_7.3.e001975.15","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.12742"},{"key":"2025090313255782000_7.3.e001975.16","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2015.05.001"}],"container-title":["RMD Open"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/rmdopen-2021-001975","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,3]],"date-time":"2025-09-03T20:26:06Z","timestamp":1756931166000},"score":1,"resource":{"primary":{"URL":"https:\/\/rmdopen.bmj.com\/lookup\/doi\/10.1136\/rmdopen-2021-001975"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,12]]},"references-count":16,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2021,12,3]]},"published-print":{"date-parts":[[2021,12]]}},"alternative-id":["10.1136\/rmdopen-2021-001975"],"URL":"https:\/\/doi.org\/10.1136\/rmdopen-2021-001975","relation":{},"ISSN":["2056-5933"],"issn-type":[{"value":"2056-5933","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,12]]}}}