{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T09:03:35Z","timestamp":1790845415417,"version":"4.1.0"},"reference-count":12,"publisher":"BMJ","issue":"2","license":[{"start":{"date-parts":[[2023,6,15]],"date-time":"2023-06-15T00:00:00Z","timestamp":1686787200000},"content-version":"unspecified","delay-in-days":14,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["RMD Open"],"accepted":{"date-parts":[[2023,5,22]]},"published-print":{"date-parts":[[2023,6]]},"abstract":"<jats:p>An European Alliance of Associations for Rheumatology task force recently recommended specific points to consider for exploring type I interferon pathway in patients, highlighting the lack of analytical assays validated for clinical routine. We report here the French experience on a type I interferon pathway assay that has been set up and used routinely since 2018 in Lyon, France.<\/jats:p>","DOI":"10.1136\/rmdopen-2023-003211","type":"journal-article","created":{"date-parts":[[2023,6,15]],"date-time":"2023-06-15T12:40:45Z","timestamp":1686832845000},"page":"e003211","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":16,"title":["Assessment of type I interferon response in routine practice in France in 2022"],"prefix":"10.1136","volume":"9","author":[{"given":"Anais","family":"Nombel","sequence":"first","affiliation":[{"name":"Immunology Laboratory, H\u00f4pital Lyon-Sud, Hospices Civils de Lyon, Lyon, France"},{"name":"International Center of Infectiology Research (CIRI), INSERM U1111, CNRS, UMR5308, ENS of Lyon, Claude Bernard University Lyon 1, Lyon, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne Perrine","family":"Foray","sequence":"additional","affiliation":[{"name":"Immunology Laboratory, H\u00f4pital Lyon-Sud, Hospices Civils de Lyon, Lyon, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lorna","family":"Garnier","sequence":"additional","affiliation":[{"name":"Immunology Laboratory, H\u00f4pital Lyon-Sud, Hospices Civils de Lyon, Lyon, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christine","family":"Lombard","sequence":"additional","affiliation":[{"name":"Immunology Laboratory, H\u00f4pital Lyon-Sud, Hospices Civils de Lyon, Lyon, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7432-847X","authenticated-orcid":false,"given":"Eric","family":"Hachulla","sequence":"additional","affiliation":[{"name":"D\u00e9partement de M\u00e9decine Interne et d'Immunologie Clinique, Centre National de R\u00e9f\u00e9rence Maladies Syst\u00e9miques et Auto-immunes Rares Nord et Nord-Ouest de France (CeRAINO), European Reference Network on Rare Connective Tissue and Musculoskeletal Diseases Network (ReCONNECT), Universit\u00e9 de Lille, CHU Lille, Lille, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brigitte","family":"Bader-Meunier","sequence":"additional","affiliation":[{"name":"Department of Paediatric Hematology-Immunology and Rheumatology, Reference center for Rheumatic, AutoImmune and Systemic diseases in children (RAISE), Necker-Enfants Malades Hospital, AP-HP, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6668-8854","authenticated-orcid":false,"given":"Sophie","family":"Georgin-Lavialle","sequence":"additional","affiliation":[{"name":"Service M\u00e9decine Interne, Centre de r\u00e9f\u00e9rence des maladies autoinflammatoires et des amyloses (CEREMAIA), H\u00f4pital Tenon, AP-HP, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8057-333X","authenticated-orcid":false,"given":"Isabelle","family":"Melki","sequence":"additional","affiliation":[{"name":"General Paediatrics, Department of Infectious Disease and Internal Medicine, Reference center for Rheumatic, AutoImmune and Systemic diseases in children (RAISE), Robert Debr\u00e9 Mother-Child University Hospital, AP-HP, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0857-8179","authenticated-orcid":false,"given":"Thierry","family":"Walzer","sequence":"additional","affiliation":[{"name":"International Center of Infectiology Research (CIRI), INSERM U1111, CNRS, UMR5308, ENS of Lyon, Claude Bernard University Lyon 1, Lyon, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4902-5332","authenticated-orcid":false,"given":"Alexandre","family":"Belot","sequence":"additional","affiliation":[{"name":"International Center of Infectiology Research (CIRI), INSERM U1111, CNRS, UMR5308, ENS of Lyon, Claude Bernard University Lyon 1, Lyon, France"},{"name":"Pediatric Nephrology, Rheumatology, Dermatology Department, National Referee Centre for Rheumatic and Autoimmune Diseases in Children (RAISE), H\u00f4pital Femme-M\u00e8re Enfant, Hospices Civils de Lyon, Lyon, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5085-443X","authenticated-orcid":false,"given":"Sebastien","family":"Viel","sequence":"additional","affiliation":[{"name":"Immunology Laboratory, H\u00f4pital Lyon-Sud, Hospices Civils de Lyon, Lyon, France"},{"name":"International Center of Infectiology Research (CIRI), INSERM U1111, CNRS, UMR5308, ENS of Lyon, Claude Bernard University Lyon 1, Lyon, France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2023,6,15]]},"reference":[{"key":"2025090312343834000_9.2.e003211.1","doi-asserted-by":"publisher","DOI":"10.1136\/ard-2022-223628"},{"key":"2025090312343834000_9.2.e003211.2","doi-asserted-by":"crossref","DOI":"10.1136\/rmdopen-2022-002876","article-title":"Type I interferon pathway assays in studies of rheumatic and musculoskeletal diseases: a systematic literature review informing EULAR points to consider","volume":"9","author":"Burska","year":"2023","journal-title":"RMD Open"},{"key":"2025090312343834000_9.2.e003211.3","doi-asserted-by":"publisher","DOI":"10.1016\/j.cyto.2018.10.023"},{"key":"2025090312343834000_9.2.e003211.4","article-title":"Development of potential pharmacodynamic and diagnostic markers for anti-IFN-\u03b1 monoclonal antibody trials in systemic lupus erythematosus","volume":"2009","author":"Yao","year":"2009","journal-title":"Hum Genomics Proteomics"},{"key":"2025090312343834000_9.2.e003211.5","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(13)70258-8"},{"key":"2025090312343834000_9.2.e003211.6","doi-asserted-by":"crossref","first-page":"802","DOI":"10.1093\/clinchem\/hvaa089","article-title":"Type I interferon in children with viral or bacterial infections","volume":"66","author":"Trouillet-Assant","year":"2020","journal-title":"Clin Chem"},{"key":"2025090312343834000_9.2.e003211.7","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20161451"},{"key":"2025090312343834000_9.2.e003211.8","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2021-221835"},{"key":"2025090312343834000_9.2.e003211.9","doi-asserted-by":"publisher","DOI":"10.1007\/s10875-016-0359-1"},{"key":"2025090312343834000_9.2.e003211.10","doi-asserted-by":"publisher","DOI":"10.1136\/ard-2022-222549"},{"key":"2025090312343834000_9.2.e003211.11","doi-asserted-by":"crossref","DOI":"10.1126\/science.abd4585","article-title":"Autoantibodies against type I IFNs in patients with life-threatening COVID-19","volume":"370","author":"Bastard","year":"2020","journal-title":"Science"},{"key":"2025090312343834000_9.2.e003211.12","doi-asserted-by":"crossref","DOI":"10.1136\/rmdopen-2022-002864","article-title":"Association between type I interferon pathway activation and clinical outcomes in rheumatic and musculoskeletal diseases: a systematic literature review informing EULAR points to consider","volume":"9","author":"Rodr\u00edguez-Carrio","year":"2023","journal-title":"RMD Open"}],"container-title":["RMD Open"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/rmdopen-2023-003211","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,3]],"date-time":"2025-09-03T19:34:44Z","timestamp":1756928084000},"score":1,"resource":{"primary":{"URL":"https:\/\/rmdopen.bmj.com\/lookup\/doi\/10.1136\/rmdopen-2023-003211"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,6]]},"references-count":12,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2023,6,15]]},"published-print":{"date-parts":[[2023,6]]}},"alternative-id":["10.1136\/rmdopen-2023-003211"],"URL":"https:\/\/doi.org\/10.1136\/rmdopen-2023-003211","relation":{},"ISSN":["2056-5933"],"issn-type":[{"value":"2056-5933","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,6]]}}}