{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T05:42:02Z","timestamp":1788586922437,"version":"build-2803163510"},"reference-count":30,"publisher":"BMJ","issue":"7","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["Sex Transm Infect"],"accepted":{"date-parts":[[2013,1,29]]},"published-print":{"date-parts":[[2013,11]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To examine lymphogranuloma venereum (LGV) trends over time among men who have sex with men (MSM) visiting the Amsterdam sexually transmitted infection (STI) clinic; to investigate anal LGV symptomatology; and to examine the positivity and characteristics of anorectal and inguinal LGV.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      We included MSM consultations from whom a swab (from anorectum, bubo or an genital ulcer) was taken for\n                      <jats:italic>Chlamydia trachomatis<\/jats:italic>\n                      (Ct) screening. Anorectal swabs were taken from all MSM who reported receptive anorectal intercourse in the preceding 6\u2005months. Ct positive samples were further tested with a\n                      <jats:italic>pmpH<\/jats:italic>\n                      PCR to identify L-genovars. Patient symptoms, clinical and anoscopic inflammatory signs, and STI co-infections were noted; Gram-stained anorectal mucosal smears were examined.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Between January 2005 and June 2012, 48\u2005570 consultations among MSM were conducted. In 3628\/35\u2005650 visits, anorectal Ct infections were diagnosed, including 411 anal LGV (1.2%). Moreover, 65\/1649 genital ulcer swabs were Ct positive; 10 were inguinal LGV (0.6%) Since January 2011 a significant increase in the positivity of LGV occurred (p&lt;0.0001). 89 (27.2%) anorectal LGV cases were asymptomatic. HIV prevalence among anorectal LGV cases was significantly higher (p=0.008) than among inguinal LGV cases. STI co-morbidity in anorectal LGV cases remained invariably high during the study period.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Since January 2011, LGV positivity in MSM consultations in Amsterdam has risen significantly. The great majority comprise anal LGV; inguinal LGV is rare. Anal LGV is asymptomatic in a quarter of cases. In all MSM with anal Ct infections LGV should be excluded, irrespective of symptoms or inflammatory signs.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1136\/sextrans-2012-050915","type":"journal-article","created":{"date-parts":[[2013,2,20]],"date-time":"2013-02-20T22:38:23Z","timestamp":1361399903000},"page":"548-552","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":87,"title":["Anorectal and inguinal lymphogranuloma venereum among men who have sex with men in Amsterdam, the Netherlands: trends over time, symptomatology and concurrent infections"],"prefix":"10.1136","volume":"89","author":[{"given":"Nynke Hesselina Neeltje","family":"de Vrieze","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martijn","family":"van Rooijen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maarten Franciscus","family":"Schim van der Loeff","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Henry John C","family":"de Vries","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2013,2,20]]},"reference":[{"key":"2024051410042814000_89.7.548.1","first-page":"985","article-title":"Centres for Disease Control (CDC) Atlanta, GA, USA. Lymphogranuloma venereum among men who have sex with men\u2014Netherlands, 2003\u20132004","volume":"53","year":"2004","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"2024051410042814000_89.7.548.2","doi-asserted-by":"publisher","DOI":"10.1086\/423966"},{"key":"2024051410042814000_89.7.548.3","doi-asserted-by":"publisher","DOI":"10.1097\/QCO.0b013e328320a8ae"},{"key":"2024051410042814000_89.7.548.4","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2334-11-70"},{"key":"2024051410042814000_89.7.548.5","doi-asserted-by":"publisher","DOI":"10.1086\/498904"},{"key":"2024051410042814000_89.7.548.6","doi-asserted-by":"publisher","DOI":"10.1258\/095646207781439739"},{"key":"2024051410042814000_89.7.548.7","doi-asserted-by":"crossref","first-page":"150","DOI":"10.2807\/esm.11.09.00642-en","article-title":"A slow epidemic of LGV in the Netherlands in 2004 and 2005","volume":"11","author":"van de Laar","year":"2006","journal-title":"Euro Surveill"},{"key":"2024051410042814000_89.7.548.8","first-page":"E31","article-title":"Lymphogranuloma venereum as a cause of rectal stricture","volume":"50","author":"Pinsk","year":"2007","journal-title":"Can J Surg"},{"key":"2024051410042814000_89.7.548.9","doi-asserted-by":"publisher","DOI":"10.1097\/01.aids.0000171412.61360.f8"},{"key":"2024051410042814000_89.7.548.10","doi-asserted-by":"publisher","DOI":"10.1086\/518796"},{"key":"2024051410042814000_89.7.548.11","doi-asserted-by":"publisher","DOI":"10.1007\/s10096-010-0959-2"},{"key":"2024051410042814000_89.7.548.12","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.2008.02573.x"},{"key":"2024051410042814000_89.7.548.13","first-page":"2544","article-title":"Inguinal lymphogranuloma venereum in a man having sex with men: perhaps an example of the missing link to explain the transmission of the recently identified anorectal epidemic","volume":"148","author":"Wolkerstorfer","year":"2004","journal-title":"Ned Tijdschr Geneeskd"},{"key":"2024051410042814000_89.7.548.14","doi-asserted-by":"publisher","DOI":"10.1097\/OLQ.0b013e31815abb08"},{"key":"2024051410042814000_89.7.548.15","doi-asserted-by":"publisher","DOI":"10.1136\/sti.2008.031773"},{"key":"2024051410042814000_89.7.548.16","doi-asserted-by":"publisher","DOI":"10.1136\/sti.2008.035311"},{"key":"2024051410042814000_89.7.548.17","unstructured":"GGD Amsterdam SOA en HIV jaarcijfers 2011. 1-4-2012 http:\/\/www.gezond.amsterdam.nl\/GetDocument.ashx?DocumentID=12274&name=SOA-HIV-jaarcijfers-2011&rnd=634690468542607609 (accessed 25 Oct 2012) Ref Type: Internet Communication."},{"key":"2024051410042814000_89.7.548.18","unstructured":"Trienekens SCM Koedijk FD van den Broek IVF . Sexually transmitted infections, including HIV, in the Netherlands in 2011. RIVM report 201051001\/2012. National Institute for Public Health and the Environment. 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Health Protection Report Vol 5 No. 24 June 2011."},{"key":"2024051410042814000_89.7.548.25","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-0691.2011.03661.x"},{"key":"2024051410042814000_89.7.548.26","doi-asserted-by":"publisher","DOI":"10.1136\/sextrans-2011-050298"},{"key":"2024051410042814000_89.7.548.27","doi-asserted-by":"publisher","DOI":"10.1086\/509922"},{"key":"2024051410042814000_89.7.548.28","doi-asserted-by":"publisher","DOI":"10.1086\/505310"},{"key":"2024051410042814000_89.7.548.29","doi-asserted-by":"publisher","DOI":"10.1136\/sextrans-2011-050458"},{"key":"2024051410042814000_89.7.548.30","unstructured":"2012 National Guideline for the management of Lymphogranuloma Venereum (LGV) Clinical Effectiveness Group of the Britisch Association for Sexual Health and HIV (CEG\/BASHH) http:\/\/www.bashh.org\/documents\/4491 (accessed 25 Oct 2012)."}],"container-title":["Sexually Transmitted Infections"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/sextrans-2012-050915","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,14]],"date-time":"2024-05-14T13:05:08Z","timestamp":1715691908000},"score":1,"resource":{"primary":{"URL":"https:\/\/sti.bmj.com\/lookup\/doi\/10.1136\/sextrans-2012-050915"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,2,20]]},"references-count":30,"journal-issue":{"issue":"7","published-online":{"date-parts":[[2013,10,11]]},"published-print":{"date-parts":[[2013,11]]}},"alternative-id":["10.1136\/sextrans-2012-050915"],"URL":"https:\/\/doi.org\/10.1136\/sextrans-2012-050915","relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.722920092.793501536","asserted-by":"object"}]},"ISSN":["1368-4973","1472-3263"],"issn-type":[{"value":"1368-4973","type":"print"},{"value":"1472-3263","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,2,20]]}}}