{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,31]],"date-time":"2026-03-31T08:25:01Z","timestamp":1774945501058,"version":"3.50.1"},"reference-count":16,"publisher":"BMJ","issue":"6","funder":[{"name":"Hologic,Inc."},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["Sex Transm Infect"],"published-print":{"date-parts":[[2018,9]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>Research exploring the clinical and sexual risk correlates is essential to define universal standards for screening and management for<jats:italic>Mycoplasma genitalium<\/jats:italic>(MG). The objective of this study is to determine the baseline prevalence of MG and associated clinical risks using cross-sectional data.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Adolescent and young adult women 13\u201329 years were recruited during clinical visits during which biological specimens were collected for<jats:italic>Neisseriagonorrhoeae<\/jats:italic>(NG) and<jats:italic>Chlamydia trachomatis<\/jats:italic>(CT) testing to provide vaginal specimens for MG and<jats:italic>Trichomonasvaginalis<\/jats:italic>(TV) testing. Demographic, clinical and sexual risk data were collected after obtaining written consent. MG was tested using the Hologic Gen-Probe transcription-mediated amplification\u2013MG analyte-specific reagent assay and TV by the Aptima TV assay. Bivariate analyses were used to evaluate differences in MG prevalence based on pregnancy status, demographic factors, clinical symptoms, concurrent STI and sexual risk behaviour quiz score (maximum score=10).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>483 patients with a mean age of 22.4 years (SD 3.6) were enrolled. Most participants were not pregnant (66%) and asymptomatic (59%). MG was the most common STI (MG 16%, TV 9%, CT 8%, NG 1%). Neither pregnancy nor symptoms were predictive of STI positivity. Thirty-five percent of non-pregnant and 45% of pregnant adolescents \u226419 years were positive for any STI. Participants with MG were 3.4 times more likely to be co-infected with other STIs compared with those with other STIs (OR 3.4, 95% CI 1.17 to 10.3, P=0.021). Mean risk quiz scores for STI positive women were six points higher than those who were STI negative (\u03b2=0.63, 95% CI 0.36 to 0.90, P&lt;0.001). There were no differences in risk scores for MG-positive participants compared with other STI positivity.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>MG infection was common, associated with STI co-infection and often asymptomatic, and pregnancy status did not confer protection.<\/jats:p><\/jats:sec>","DOI":"10.1136\/sextrans-2017-053367","type":"journal-article","created":{"date-parts":[[2018,3,29]],"date-time":"2018-03-29T16:15:21Z","timestamp":1522340121000},"page":"411-413","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":25,"title":["Clinical and sexual risk correlates of<i>Mycoplasma genitalium<\/i>in urban pregnant and non-pregnant young women: cross-sectional outcomes using the baseline data from the Women\u2019s BioHealth Study"],"prefix":"10.1136","volume":"94","author":[{"given":"Maria","family":"Trent","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jenell S","family":"Coleman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Justin","family":"Hardick","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jamie","family":"Perin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lisa","family":"Tabacco","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Steven","family":"Huettner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jocelyn","family":"Ronda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rebecca","family":"Felter-Wernsdorfer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Charlotte A","family":"Gaydos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2018,3,29]]},"reference":[{"key":"2020050723333943000_94.6.411.1","doi-asserted-by":"publisher","DOI":"10.1155\/2011\/942937"},{"key":"2020050723333943000_94.6.411.2","doi-asserted-by":"crossref","first-page":"44","DOI":"10.33590\/emjreprohealth\/10311621","article-title":"Recruitment of minority adolescents and young adults into randomized clinical trials: testing the design of the Technology Enhanced Community Health Nursing (TECH-N) Pelvic Inflammatory Disease Trial","volume":"2","author":"Trent","year":"2016","journal-title":"EMJ Repro Health"},{"key":"2020050723333943000_94.6.411.3","doi-asserted-by":"publisher","DOI":"10.1097\/OLQ.0b013e3181f2e85f"},{"key":"2020050723333943000_94.6.411.4","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciu217"},{"key":"2020050723333943000_94.6.411.5","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cit752"},{"key":"2020050723333943000_94.6.411.6","unstructured":"U.S. Department of Health and Human Services. Healthy People. 2020 http:\/\/www.healthypeople.gov\/2020\/default.aspx (accessed 30 Sep 2016)."},{"key":"2020050723333943000_94.6.411.7","unstructured":"Baltimore City Health Department. HIV\/STD Data Sources. http:\/\/health.baltimorecity.gov\/hivstd-data-resources (accessed 12 Nov 2017)."},{"key":"2020050723333943000_94.6.411.8","doi-asserted-by":"publisher","DOI":"10.1136\/sextrans-2015-052058"},{"key":"2020050723333943000_94.6.411.9","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.44.4.1236-1240.2006"},{"key":"2020050723333943000_94.6.411.10","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/civ771"},{"issue":"suppl_2","key":"2020050723333943000_94.6.411.11","doi-asserted-by":"crossref","first-page":"S406","DOI":"10.1093\/infdis\/jix104","article-title":"Mycoplasma genitalium: accurate diagnosis is necessary for adequate treatment","volume":"216","author":"Gaydos","year":"2017","journal-title":"J Infect Dis"},{"key":"2020050723333943000_94.6.411.12","doi-asserted-by":"publisher","DOI":"10.1093\/ije\/dyv194"},{"key":"2020050723333943000_94.6.411.13","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/civ312"},{"key":"2020050723333943000_94.6.411.14","unstructured":"Centers for Disease Control and Prevention. US. Department of Health and Human Services. Sexually Transmitted Disease Surveillance. 2014 http:\/\/www.cdc.gov\/std\/stats (accessed 30 Jan 2016)."},{"key":"2020050723333943000_94.6.411.15","unstructured":"Baltimore City Health Department. Baltimore City STD Data\u2014Reported through March 2014. http:\/\/health.baltimorecity.gov\/sites\/default\/files\/Copy_of_STD_Trends-HealthStat.pdf (accessed 19 Nov 2016)."},{"key":"2020050723333943000_94.6.411.16","unstructured":"Maryland Department of Health and Mental Hygiene. Chlamydia in Maryland. http:\/\/phpa.dhmh.maryland.gov\/OIDPCS\/CSTIP\/SitePages\/chlamydia.html (accessed 19 Nov 2016)."}],"container-title":["Sexually Transmitted Infections"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/sextrans-2017-053367","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T21:02:57Z","timestamp":1693602177000},"score":1,"resource":{"primary":{"URL":"https:\/\/sti.bmj.com\/lookup\/doi\/10.1136\/sextrans-2017-053367"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,3,29]]},"references-count":16,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2018,8,20]]},"published-print":{"date-parts":[[2018,9]]}},"alternative-id":["10.1136\/sextrans-2017-053367"],"URL":"https:\/\/doi.org\/10.1136\/sextrans-2017-053367","relation":{},"ISSN":["1368-4973","1472-3263"],"issn-type":[{"value":"1368-4973","type":"print"},{"value":"1472-3263","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,3,29]]}}}