{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T07:06:18Z","timestamp":1790665578727,"version":"4.1.0"},"reference-count":26,"publisher":"BMJ","issue":"6","funder":[{"DOI":"10.13039\/100000060","name":"National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]},{"name":"National Insitute of Allergy and Infectious Diseases"}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["Sex Transm Infect"],"accepted":{"date-parts":[[2018,2,17]]},"published-print":{"date-parts":[[2018,9]]},"abstract":"<jats:sec>\n                  <jats:title>Objective<\/jats:title>\n                  <jats:p>Assess risk factors for incident and endometrial <jats:italic>Mycoplasma genitalium<\/jats:italic> infection and determine if <jats:italic>M. genitalium<\/jats:italic> is associated with histological endometritis, an indicator of pelvic inflammatory disease.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>This study was a secondary data analysis within the T cell Response Against Chlamydia (TRAC) Study, a prospective evaluation of 246 women with or at risk for <jats:italic>Chlamydia trachomatis<\/jats:italic> from urban outpatient clinics, who were followed quarterly for 12 months. Risk factors for incident <jats:italic>M. genitalium<\/jats:italic> infection were determined by Cox regression. Relative risks were estimated by Poisson regression with robust error measurements for models examining the association between <jats:italic>M. genitalium<\/jats:italic> and endometritis (histological evidence of plasma cells in endometrial stroma and neutrophils in the endometrial epithelium) and for models examining risk factors for detection of endometrial <jats:italic>M. genitalium<\/jats:italic> infection.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>\n                     <jats:italic>M. genitalium<\/jats:italic> prevalence was 16.7%, incidence was 25.3 per 100 person-years and 23% had repeated positive tests. Black race (non-black HR<jats:sub>adj<\/jats:sub> 0.4, 95%\u2009CI 0.2 to 0.9), less education (HR<jats:sub>adj<\/jats:sub> 2.4, 95%\u2009CI 1.2 to 5.1) and a new sexual partner (HR<jats:sub>adj<\/jats:sub> 3.1, 95%\u2009CI 1.7 to 5.4) were associated with incident <jats:italic>M. genitalium. M. genitalium<\/jats:italic> was associated with endometritis (RR<jats:sub>adj<\/jats:sub> 2.0, 95%\u2009CI 1.1 to 3.7). <jats:italic>Trichomonas vaginalis<\/jats:italic> (RR<jats:sub>adj<\/jats:sub> 2.0, 95%\u2009CI 1.2 to 3.4) and endometrial <jats:italic>C. trachomatis<\/jats:italic> (RR<jats:sub>adj<\/jats:sub> 1.7, 95%\u2009CI 1.1 to 2.8) were associated with endometrial <jats:italic>M. genitalium<\/jats:italic>.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>\n                     <jats:italic>M. genitalium<\/jats:italic> is prevalent in women at high risk for <jats:italic>C. trachomatis<\/jats:italic>, persists over multiple follow-up visits and is associated with histological endometritis. Studies are needed to determine if screening for <jats:italic>M. genitalium<\/jats:italic> will improve reproductive outcomes.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1136\/sextrans-2017-053376","type":"journal-article","created":{"date-parts":[[2018,3,21]],"date-time":"2018-03-21T12:15:37Z","timestamp":1521634537000},"page":"414-420","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":30,"title":["Risk factors for <i>Mycoplasma genitalium<\/i> endometritis and incident infection: a secondary data analysis of the T cell Response Against Chlamydia (TRAC) Study"],"prefix":"10.1136","volume":"94","author":[{"given":"Brandie D","family":"Taylor","sequence":"first","affiliation":[{"name":"Department of Epidemiology and Biostatistics, School of Public Health, Texas A&M University, College Station, Texas, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaojing","family":"Zheng","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, University of North Carolina Chapel Hill, Chapel Hill, North Carolina, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherine M","family":"O\u2019Connell","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, University of North Carolina Chapel Hill, Chapel Hill, North Carolina, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harold C","family":"Wiesenfeld","sequence":"additional","affiliation":[{"name":"Department of Obstetrics, Gynecology and Reproductive Sciences, University of Pittsburgh and Magee-Womens Research Institute, Pittsburgh, Pennsylvania, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sharon L","family":"Hillier","sequence":"additional","affiliation":[{"name":"Department of Obstetrics, Gynecology and Reproductive Sciences, University of Pittsburgh and Magee-Womens Research Institute, Pittsburgh, Pennsylvania, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toni","family":"Darville","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, University of North Carolina Chapel Hill, Chapel Hill, North Carolina, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2018,3,21]]},"reference":[{"key":"2025081305130940000_94.6.414.1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/civ312"},{"key":"2025081305130940000_94.6.414.2","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.00006-11"},{"key":"2025081305130940000_94.6.414.3","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.00840-09"},{"key":"2025081305130940000_94.6.414.4","first-page":"417","article-title":"Acute upper genital-tract disease in female monkeys provoked experimentally by Mycoplasma 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Multidrug-Resistant Mycoplasma genitalium in Human Immunodeficiency Virus-infected Men who have Sex with Men in Alabama","volume":"66","author":"Dionne-Odom","year":"2018","journal-title":"Clin Infect Dis"},{"key":"2025081305130940000_94.6.414.13","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jiv438"},{"key":"2025081305130940000_94.6.414.14","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(83)91112-9"},{"key":"2025081305130940000_94.6.414.15","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-199002000-00008"},{"key":"2025081305130940000_94.6.414.16","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0015660","article-title":"Genetic variation in the complete MgPa operon and its repetitive chromosomal elements in clinical strains of Mycoplasma genitalium","volume":"5","author":"Ma","year":"2010","journal-title":"PLoS 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