{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,25]],"date-time":"2025-10-25T11:29:03Z","timestamp":1761391743814,"version":"3.41.0"},"reference-count":22,"publisher":"BMJ","issue":"7","funder":[{"DOI":"10.13039\/501100000106","name":"Saskatchewan Health Research Foundation","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100000106","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["Sex Transm Infect"],"published-print":{"date-parts":[[2018,11]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>A<jats:italic>Neisseria gonorrhoeae<\/jats:italic>antimicrobial susceptibility quality control comparison programme was re-established in Latin America and the Caribbean to ensure antimicrobial susceptibility data produced from the region are comparable nationally and internationally.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Three panels, consisting of<jats:italic>N. gonorrhoeae<\/jats:italic>isolates comprising reference strains and other characterised isolates were sent to 11 participating laboratories between 2013 and 2015. Antimicrobial susceptibilities for these isolates were determined using agar dilution, Etest or disc diffusion methods. Modal minimum inhibitory concentrations (MICs) for each panel isolate\/antibiotic combination were calculated. The guidelines of the Clinical and Laboratory Standards Institute were used for interpretations of antimicrobial susceptibility. The agreement of MICs with the modal MICs was determined for each of the participating laboratories as well as for each of the antibiotics tested.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Five of 11 laboratories that participated in at least one panel had an overall average agreement between participants\u2019 MIC results and modal MICs of &gt;90%. For other laboratories, agreements ranged from 60.0% to 82.4%. The proportion of agreement between interpretations for all the antibiotics, except penicillin and tetracycline, was &gt;90%. The percentages of agreement between MIC results and their modes for erythromycin, spectinomycin, cefixime and azithromycin were &gt;90%. Tetracycline, ceftriaxone and ciprofloxacin agreement ranged from 84.5% to 89.1%, while penicillin had 78.8% agreement between MICs and modal MICs.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The participating laboratories had acceptable results, similar to other international quality assurance programmes. It is important to ensure continuation of the International Gonococcal Antimicrobial Susceptibility Quality Control Comparison Programme to ensure that participants can identify and correct any problems in antimicrobial susceptibility testing for<jats:italic>N. gonorrhoeae<\/jats:italic>as they arise and continue to generate reproducible and reliable data.<\/jats:p><\/jats:sec>","DOI":"10.1136\/sextrans-2017-053502","type":"journal-article","created":{"date-parts":[[2018,4,19]],"date-time":"2018-04-19T16:15:29Z","timestamp":1524154529000},"page":"479-482","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":8,"title":["Quality assurance for antimicrobial susceptibility testing of<i>Neisseria gonorrhoeae<\/i>in Latin American and Caribbean countries, 2013\u20132015"],"prefix":"10.1136","volume":"94","author":[{"given":"Pam","family":"Sawatzky","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Irene","family":"Martin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patricia","family":"Galarza","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mar\u0131a Elena Trigoso","family":"Carvallo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pamela","family":"Araya Rodriguez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Olga Marina Sanabria","family":"Cruz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alina Llop","family":"Hernandez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mario Fabian","family":"Martinez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Graciela","family":"Borthagaray","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daisy","family":"Payares","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos\u00e9 E","family":"Moreno","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marina","family":"Chiappe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aura Helena","family":"Corredor","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sidharath Dev","family":"Thakur","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jo-Anne R","family":"Dillon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2018,4,19]]},"reference":[{"key":"2020050723335274000_94.7.479.1","doi-asserted-by":"crossref","unstructured":"Newman L , Rowley J , Vander Hoorn S , et al . Global estimates of the prevalence and incidence of four curable sexually transmitted infections in 2012 based on systematic review and global reporting. PLoS One 2015;10:e0143304.doi:10.1371\/journal.pone.0143304","DOI":"10.1371\/journal.pone.0143304"},{"key":"2020050723335274000_94.7.479.2","doi-asserted-by":"publisher","DOI":"10.1097\/QCO.0000000000000025"},{"key":"2020050723335274000_94.7.479.3","doi-asserted-by":"publisher","DOI":"10.1136\/sextrans-2012-050905"},{"key":"2020050723335274000_94.7.479.4","unstructured":"Li H , Dillon JR . International antimicrobial susceptibility testing quality control program for Neisseria gonorrhoeae . Proceedings of International Congress of Sexually Transmitted Diseases. Madrid, Spain, 1997."},{"key":"2020050723335274000_94.7.479.5","unstructured":"World Health Organization. Global action plan to control the spread and impact of antimicrobial resistance in Neisseria gonorrhoeae. Geneva, Switzerland: World Health Organization, 2012."},{"key":"2020050723335274000_94.7.479.6","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkp098"},{"key":"2020050723335274000_94.7.479.7","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1016\/j.mimet.2017.11.011","article-title":"Suitability of a chocolate agar-based medium for the transportation and long term storage of Neisseria gonorrhoeae isolates at room temperature","volume":"144","author":"Thakur","year":"2018","journal-title":"J Microbiol Methods"},{"key":"2020050723335274000_94.7.479.8","unstructured":"Clinical and Laboratory Standards Institute. Methods for dilution dntimicrobial susceptibility tests for bacteria that grow aerobically; M07-A10. Wayne, PA, USA: CLSI, 2015."},{"key":"2020050723335274000_94.7.479.9","unstructured":"bioMerieux. Etest application guide. http:\/\/www.biomerieux-usa.com\/sites\/subsidiary_us\/files\/supplementary_inserts_-_16273_-_b_-_en_-_eag_-_etest_application_guide-3.pdf (accessed 24 Apr 2017)."},{"key":"2020050723335274000_94.7.479.10","unstructured":"Clinical Laboratory Standards Institute. Performance standards for antimicrobial disk susceptibility tests: MO2-A12:2015. Wayne, PA, USA: CLSI, 2015."},{"key":"2020050723335274000_94.7.479.11","unstructured":"Clinical and Laboratory Standards Institute. Performance standards for antimicrobial susceptibility testing: M100-S27. Wayne, PA, USA: CLSI, 2017."},{"key":"2020050723335274000_94.7.479.12","doi-asserted-by":"publisher","DOI":"10.1097\/00007435-199607000-00004"},{"key":"2020050723335274000_94.7.479.13","unstructured":"Centers of Disease Control and Prevention. Gonococcal isolate surveillance project (GISP) protocol. Activities and responsibilities: US Department of Health and Human Services, Centers for Disease Control and Prevention. https:\/\/www.cdc.gov\/std\/gisp\/gisp-protocol-may-2016.pdf. (accessed 9 Apr 2017)."},{"key":"2020050723335274000_94.7.479.14","unstructured":"Clinical and Laboratory Standards Institute. Development of in vitro\u00a0susceptibility testing criteria and quality control parameters: M23-A3. Wayne, PA, USA: CLSI, 2008."},{"key":"2020050723335274000_94.7.479.15","doi-asserted-by":"crossref","first-page":"2841","DOI":"10.1128\/JCM.31.11.2841-2844.1993","article-title":"Selection criteria for an antimicrobial susceptibility testing system","volume":"31","author":"Jorgensen","year":"1993","journal-title":"J Clin Microbiol"},{"key":"2020050723335274000_94.7.479.16","doi-asserted-by":"publisher","DOI":"10.1097\/01.olq.0000187231.28812.29"},{"key":"2020050723335274000_94.7.479.17","doi-asserted-by":"crossref","first-page":"E60","DOI":"10.33321\/cdi.2017.41.9","article-title":"Australian Gonococcal Surveillance Programme annual report, 2015","volume":"41","author":"Lahra","year":"2017","journal-title":"Commun Dis Intell Q Rep"},{"key":"2020050723335274000_94.7.479.18","first-page":"8","article-title":"Use of a quality assurance scheme in a long-term multicentric study of antibiotic susceptibility of Neisseria gonorrhoeae","volume":"66","author":"Tapsall","year":"1990","journal-title":"Genitourin Med"},{"key":"2020050723335274000_94.7.479.19","doi-asserted-by":"publisher","DOI":"10.1017\/S0950268809990148"},{"key":"2020050723335274000_94.7.479.20","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.02303-15"},{"key":"2020050723335274000_94.7.479.21","unstructured":"Cole M , Pitt R , Chisholm S , et al . Gonococcal antimicrobial susceptibility surveillance in Europe, 2011, 2013. ISBN 978-92-9193-450-8, ISSN 1977-4435."},{"key":"2020050723335274000_94.7.479.22","unstructured":"Cole M , Pitt R , Unemo M , et al . Gonococcal antimicrobial susceptibility surveillance in Europe, 2012, 2014. ISBN 978-92-9193-583-3, ISSN 2315-0947."}],"container-title":["Sexually Transmitted Infections"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/sextrans-2017-053502","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,7,3]],"date-time":"2025-07-03T19:51:21Z","timestamp":1751572281000},"score":1,"resource":{"primary":{"URL":"https:\/\/sti.bmj.com\/lookup\/doi\/10.1136\/sextrans-2017-053502"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,4,19]]},"references-count":22,"journal-issue":{"issue":"7","published-online":{"date-parts":[[2018,10,18]]},"published-print":{"date-parts":[[2018,11]]}},"alternative-id":["10.1136\/sextrans-2017-053502"],"URL":"https:\/\/doi.org\/10.1136\/sextrans-2017-053502","relation":{},"ISSN":["1368-4973","1472-3263"],"issn-type":[{"type":"print","value":"1368-4973"},{"type":"electronic","value":"1472-3263"}],"subject":[],"published":{"date-parts":[[2018,4,19]]}}}