{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T01:19:52Z","timestamp":1783473592962,"version":"3.55.0"},"reference-count":10,"publisher":"BMJ","issue":"1","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["Sex Transm Infect"],"accepted":{"date-parts":[[2018,11,15]]},"published-print":{"date-parts":[[2020,2]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>A human papillomavirus (HPV) vaccination programme targeted towards men who have sex with men who are disproportionately affected by HPV anogenital infection and related disease was established in Scotland in July 2017. We aimed to establish a baseline HPV prevalence to assess the potential impact of the programme.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Residual rectal swabs taken in a sexual health clinic (n=1 248) were tested for the presence of HPV and HPV-type prevalence was collated and stratified by age. Prevalence of HPV types included in the quadrivalent and nonavalent vaccines was specifically assessed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>72.8% (95% CI 70.2% to 75.3%) of swabs were positive for HPV with 59.1% (95% CI 56.3% to 61.9%) of samples positive for at least one high-risk type. A least one of HPV 6, 11, 16 and 18 was detected in approximately half of the swabs. HPV prevalence generally increased with age but did not significantly differ between older age groups. The presence of more than one HPV type increased with age and over half of samples had multiple types present.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>While HPV prevalence in this population is high, the potential impact of the vaccination programme is substantial given that 50% are not infected with a vaccine type. Defining a preimmunisation baseline in this group will be important for longitudinal monitoring of impact.<\/jats:p><\/jats:sec>","DOI":"10.1136\/sextrans-2018-053668","type":"journal-article","created":{"date-parts":[[2019,1,13]],"date-time":"2019-01-13T22:25:14Z","timestamp":1547418314000},"page":"55-57","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":8,"title":["Baseline HPV prevalence in rectal swabs from men attending a sexual health clinic in Scotland: assessing the potential impact of a selective HPV vaccination programme for men who have sex with men"],"prefix":"10.1136","volume":"96","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8720-1563","authenticated-orcid":false,"given":"Ross Liam","family":"Cameron","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kate","family":"Cuschieri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kevin G J","family":"Pollock","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2019,1,13]]},"reference":[{"key":"2024092304050829000_96.1.55.1","unstructured":"The Joint Committee on Vaccination and Immunisation . JCVI statement on HPV vaccination of men who have sex with men. Department of Health. 2018. Available: https:\/\/www.gov.uk\/government\/publications\/jcvi-statement-on-hpv-vaccination-of-men-who-have-sex-with-men [Accessed April 2018]."},{"key":"2024092304050829000_96.1.55.2","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1016\/S1473-3099(17)30653-9","article-title":"Human papillomavirus types from infection to cancer in the anus, according to sex and HIV status: a systematic review and meta-analysis","volume":"18","author":"Lin","year":"2018","journal-title":"Lancet Infect Dis"},{"key":"2024092304050829000_96.1.55.3","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2013.50.3870"},{"key":"2024092304050829000_96.1.55.4","doi-asserted-by":"crossref","DOI":"10.1186\/1756-0500-3-280","article-title":"Quality of life of homosexual males with genital warts: a qualitative study","volume":"3","author":"Lee Mortensen","year":"2010","journal-title":"BMC Res Notes"},{"key":"2024092304050829000_96.1.55.5","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(12)70080-3"},{"key":"2024092304050829000_96.1.55.6","doi-asserted-by":"publisher","DOI":"10.1038\/bjc.2015.90"},{"key":"2024092304050829000_96.1.55.7","doi-asserted-by":"publisher","DOI":"10.1136\/sextrans-2015-052032"},{"key":"2024092304050829000_96.1.55.8","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1097\/OLQ.0000000000000716","article-title":"Age-specific pattern of anogenital warts in men who have sex with men","volume":"45","author":"Ong","year":"2018","journal-title":"Sex Transm Dis"},{"key":"2024092304050829000_96.1.55.9","unstructured":"British Association for Sexual Health and HIV . BASHH CEG guidance on test for Sexually Transmitted Infections. 2015. Available: https:\/\/www.bashhguidelines.org\/media\/1084\/sti-testing-tables-2015-dec-update-4.pdf [Accessed April 2018]."},{"key":"2024092304050829000_96.1.55.10","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1010971"}],"container-title":["Sexually Transmitted Infections"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/sextrans-2018-053668","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,9,23]],"date-time":"2024-09-23T11:05:45Z","timestamp":1727089545000},"score":1,"resource":{"primary":{"URL":"https:\/\/sti.bmj.com\/lookup\/doi\/10.1136\/sextrans-2018-053668"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,1,13]]},"references-count":10,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2020,1,20]]},"published-print":{"date-parts":[[2020,2]]}},"alternative-id":["10.1136\/sextrans-2018-053668"],"URL":"https:\/\/doi.org\/10.1136\/sextrans-2018-053668","relation":{},"ISSN":["1368-4973","1472-3263"],"issn-type":[{"value":"1368-4973","type":"print"},{"value":"1472-3263","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,1,13]]}}}