{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T07:05:02Z","timestamp":1790665502883,"version":"4.1.0"},"reference-count":60,"publisher":"BMJ","issue":"8","funder":[{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["1091536"],"award-info":[{"award-number":["1091536"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Australian Government Research Training Program"}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["Sex Transm Infect"],"accepted":{"date-parts":[[2020,3,20]]},"published-print":{"date-parts":[[2020,12]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>\n                      To systematically review and appraise published data, to determine the prevalence of\n                      <jats:italic>Mycoplasma genitalium<\/jats:italic>\n                      (MG) in men who have sex with men (MSM) tested at each anatomical site, that is, at the urethra, rectum and\/or pharynx.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>Systematic review and meta-analysis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Data sources<\/jats:title>\n                    <jats:p>Ovid Medline, PubMed, Embase were searched for articles from 1st January 1981 (the year MG was first identified) to 1st June 2018.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Review methods<\/jats:title>\n                    <jats:p>Studies were eligible for inclusion if they reported MG prevalence in MSM tested at the urethra, rectum and\/or pharynx, in at least 50 MSM, using nucleic acid amplification testing. Data were extracted by anatomical site, symptom and HIV status. Summary estimates (95% CIs) were calculated using random-effects meta-analysis. Subgroup analyses were performed to assess heterogeneity between studies.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Forty-six studies met inclusion criteria, with 34 reporting estimates of MG prevalence at the urethra (13\u2009753 samples), 25 at the rectum (8629 samples) and 7 at the pharynx (1871 samples). MG prevalence was 5.0% (95% CI 3.5 to 6.8; I\n                      <jats:sup>2<\/jats:sup>\n                      =94.0) at the urethra; 6.2% (95% CI 4.6 to 8.1; I\n                      <jats:sup>2<\/jats:sup>\n                      =88.1) at the rectum and 1.0% (95% CI 0.0 to 5.1; I\n                      <jats:sup>2<\/jats:sup>\n                      =96.0) at the pharynx. The prevalence of MG was significantly higher at urethral and rectal sites in symptomatic versus asymptomatic MSM (7.1% vs 2.2%, p&lt;0.001; and 16.1% vs 7.5%, p=0.039, respectively). MG prevalence at the urethra was significantly higher in HIV-positive compared with HIV-negative MSM (7.0% vs 3.4%, p=0.006).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>MG was common in MSM, particularly at urethral and rectal sites (5% to 6%). MG was more commonly detected in symptomatic men at both sites, and more common in HIV-positive men at the urethra. MG was uncommonly detected in the pharynx. Site-specific estimates are similar to those for chlamydia and will be helpful in informing testing practices in MSM.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>PROSPERO registration number<\/jats:title>\n                    <jats:p>CRD42017058326.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1136\/sextrans-2019-054310","type":"journal-article","created":{"date-parts":[[2020,4,27]],"date-time":"2020-04-27T17:19:51Z","timestamp":1588007991000},"page":"563-570","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":41,"title":["Prevalence of\n                    <i>Mycoplasma genitalium<\/i>\n                    by anatomical site in men who have sex with men: a systematic review and meta-analysis"],"prefix":"10.1136","volume":"96","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0940-3722","authenticated-orcid":false,"given":"Rosie L","family":"Latimer","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hannah S","family":"Shilling","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3679-9195","authenticated-orcid":false,"given":"Lenka A","family":"Vodstrcil","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dorothy A","family":"Machalek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher K","family":"Fairley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1766-0657","authenticated-orcid":false,"given":"Eric P F","family":"Chow","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tim RH","family":"Read","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catriona S","family":"Bradshaw","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2020,4,27]]},"reference":[{"key":"2024092304051015000_96.8.563.1","doi-asserted-by":"publisher","DOI":"10.1136\/sextrans-2017-053384"},{"key":"2024092304051015000_96.8.563.2","doi-asserted-by":"crossref","first-page":"S759","DOI":"10.1093\/cid\/civ771","article-title":"Centers for disease control and prevention sexually transmitted diseases treatment guidelines","volume":"61 Suppl 8","author":"Workowski","year":"2015","journal-title":"Clin Infect Dis"},{"key":"2024092304051015000_96.8.563.3","unstructured":"Clutterbuck D , Asboe D , Barber T , et al . United Kingdom national guideline on the sexual health care of men who have sex with men. Int J STD AIDS 2016:0956462417746897."},{"key":"2024092304051015000_96.8.563.4","unstructured":"MSM - Men who have sex with men Australasian Sexual Health Alliance: Australian Goverment Department of Health, 2016. 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