{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,31]],"date-time":"2026-03-31T08:25:03Z","timestamp":1774945503081,"version":"3.50.1"},"reference-count":34,"publisher":"BMJ","issue":"6","funder":[{"DOI":"10.13039\/100000026","name":"National Institute on Drug Abuse","doi-asserted-by":"publisher","award":["F32DA046313"],"award-info":[{"award-number":["F32DA046313"]}],"id":[{"id":"10.13039\/100000026","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000026","name":"National Institute on Drug Abuse","doi-asserted-by":"publisher","award":["U01DA036939"],"award-info":[{"award-number":["U01DA036939"]}],"id":[{"id":"10.13039\/100000026","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["Sex Transm Infect"],"accepted":{"date-parts":[[2020,9,27]]},"published-print":{"date-parts":[[2021,9]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>This investigation sought to characterise risk factors associated with acquisition of traditional and emerging agents of sexually transmitted infection (STI) in a cohort of young men who have sex with men and transgender women.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>917 participants provided urine and rectal swab submissions assessed by transcription-mediated amplification (TMA)-based assays for<jats:italic>Chlamydia trachomatis<\/jats:italic>and<jats:italic>Neisseria gonorrhoeae<\/jats:italic>and by off-label TMA-based<jats:italic>Trichomonas vaginalis<\/jats:italic>and<jats:italic>Mycoplasma genitalium<\/jats:italic>testing. A subset provided specimens at 6-month and 12-month follow-up visits.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Prevalence of<jats:italic>M. genitalium<\/jats:italic>from rectal and urine specimens (21.7% and 8.9%, respectively) exceeded that of<jats:italic>C. trachomatis<\/jats:italic>(8.8% and 1.6%) and other STI agents. Black participants yielded higher prevalence of<jats:italic>M. genitalium<\/jats:italic>(30.6%) than non-black participants (17.0%; \u03c7\u00b2=22.39; p&lt;0.0001).<jats:italic>M. genitalium<\/jats:italic>prevalence from rectal specimens was 41.5% in HIV-positive participants vs 16.3% in HIV-negative participants (\u03c7\u00b2=57.72; p&lt;0.0001). Participant age, gender identity, condomless insertive anal\/vaginal sexual practice and condomless receptive anal sexual practice were not associated with rectal<jats:italic>C. trachomatis<\/jats:italic>(p\u22650.10),<jats:italic>N. gonorrhoeae<\/jats:italic>(p\u22650.29),<jats:italic>T. vaginalis<\/jats:italic>(p\u22650.18) or<jats:italic>M. genitalium<\/jats:italic>(p\u22650.20) detection. While prevalence of<jats:italic>T. vaginalis<\/jats:italic>was calculated at \u22641.0%, baseline rectal and urine screening status was predictive of detection\/non-detection at follow-up. A non-reactive<jats:italic>M. genitalium<\/jats:italic>baseline rectal or urine screening result was less predictive of non-reactive follow-up versus<jats:italic>C. trachomatis<\/jats:italic>,<jats:italic>N. gonorrhoeae<\/jats:italic>and<jats:italic>T. vaginalis<\/jats:italic>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Rectal<jats:italic>M. genitalium<\/jats:italic>detection is associated with black race and HIV seropositivity. Baseline<jats:italic>M. genitalium<\/jats:italic>infection influences subsequent detection of the organism.<\/jats:p><\/jats:sec>","DOI":"10.1136\/sextrans-2020-054463","type":"journal-article","created":{"date-parts":[[2020,10,29]],"date-time":"2020-10-29T21:20:27Z","timestamp":1604006427000},"page":"434-440","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":11,"title":["Molecular screening in a longitudinal cohort of young men who have sex with men and young transgender women: associations with focus on the emerging sexually transmitted pathogen<i>Mycoplasma genitalium<\/i>"],"prefix":"10.1136","volume":"97","author":[{"given":"Erik","family":"Munson","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ethan","family":"Morgan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura","family":"Sienkiewicz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yazmine","family":"Thomas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kathleen","family":"Buehler","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel","family":"Ryan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9860-4555","authenticated-orcid":false,"given":"Antonia","family":"Clifford","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9222-5116","authenticated-orcid":false,"given":"Brian","family":"Mustanski","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2020,10,29]]},"reference":[{"key":"2024092104100709000_97.6.434.1","doi-asserted-by":"publisher","DOI":"10.1007\/s11904-019-00446-5"},{"key":"2024092104100709000_97.6.434.2","doi-asserted-by":"publisher","DOI":"10.1089\/aid.2015.0013"},{"key":"2024092104100709000_97.6.434.3","doi-asserted-by":"publisher","DOI":"10.1007\/s10461-019-02766-4"},{"key":"2024092104100709000_97.6.434.4","doi-asserted-by":"publisher","DOI":"10.1097\/OLQ.0b013e3181e50058"},{"key":"2024092104100709000_97.6.434.5","doi-asserted-by":"publisher","DOI":"10.1177\/0956462416636780"},{"key":"2024092104100709000_97.6.434.6","doi-asserted-by":"publisher","DOI":"10.1097\/QAI.0000000000000933"},{"key":"2024092104100709000_97.6.434.7","doi-asserted-by":"publisher","DOI":"10.1097\/OLQ.0000000000000636"},{"key":"2024092104100709000_97.6.434.8","doi-asserted-by":"publisher","DOI":"10.1016\/j.amepre.2018.04.026"},{"key":"2024092104100709000_97.6.434.9","doi-asserted-by":"publisher","DOI":"10.1097\/OLQ.0b013e318177ec39"},{"key":"2024092104100709000_97.6.434.10","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.00185-12"},{"key":"2024092104100709000_97.6.434.11","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.00074-09"},{"key":"2024092104100709000_97.6.434.12","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.rr6404a1"},{"key":"2024092104100709000_97.6.434.13","doi-asserted-by":"crossref","first-page":"748","DOI":"10.1097\/OLQ.0000000000001244","article-title":"Comprehensive molecular screening in a cohort of young men who have sex with men and transgender women: effect of additive rectal specimen source collection and analyte testing","volume":"47","author":"Munson","year":"2020","journal-title":"Sex Transm Dis"},{"key":"2024092104100709000_97.6.434.14","doi-asserted-by":"publisher","DOI":"10.1097\/QAI.0000000000001886"},{"key":"2024092104100709000_97.6.434.15","doi-asserted-by":"publisher","DOI":"10.1007\/s10461-018-2159-5"},{"key":"2024092104100709000_97.6.434.16","unstructured":"Centers for Disease Control and Prevention and Association of Public Health Laboratories . 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