{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,2]],"date-time":"2026-04-02T16:32:35Z","timestamp":1775147555363,"version":"3.50.1"},"reference-count":26,"publisher":"BMJ","issue":"5","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["Sex Transm Infect"],"accepted":{"date-parts":[[2020,7,12]]},"published-print":{"date-parts":[[2021,8]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>International guidelines recommend<jats:italic>Mycoplasma genitalium<\/jats:italic>testing, preferably using an assay to detect macrolide resistance-associated mutations, for men presenting with non-gonococcal urethritis, but there is no specific guidance on such testing for men with gonococcal urethritis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This study aimed to estimate the proportion of men with gonococcal urethritis who have coinfection with<jats:italic>M. genitalium<\/jats:italic>through a retrospective analysis of cases of symptomatic urethral gonorrhoea at Western Sydney Sexual Health Centre in 2017 and 2018.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Fourteen of 184 (7.6%, 95%\u2009CI 3.7 to 11.5) men with gonococcal urethritis had<jats:italic>M. genitalium<\/jats:italic>detected in the urine at the time of presentation. No demographic or behavioural factors predicted<jats:italic>M. genitalium<\/jats:italic>coinfection. Coinfection with urethral<jats:italic>Chlamydia trachomatis<\/jats:italic>was detected in 29 of 184 (15.8%, 95%\u2009CI 10.5 to 21.1). All five men with macrolide-resistant<jats:italic>M. genitalium<\/jats:italic>detected returned for treatment with moxifloxacin at a median of 8 days (range 5\u201316 days) after presentation and treatment of gonorrhoea; three of five were documented to remain symptomatic at this visit.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Although<jats:italic>M. genitalium<\/jats:italic>coinfection is less common than chlamydia among men with symptomatic gonococcal urethritis,<jats:italic>M. genitalium<\/jats:italic>testing, using an assay to detect macrolide resistance, will potentially reduce symptom duration particularly for men with macrolide-resistant infections, but may not be justifiable on cost-benefit analysis.<\/jats:p><\/jats:sec>","DOI":"10.1136\/sextrans-2020-054529","type":"journal-article","created":{"date-parts":[[2020,9,10]],"date-time":"2020-09-10T21:26:12Z","timestamp":1599773172000},"page":"363-367","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":11,"title":["<i>Mycoplasma genitalium<\/i>coinfection in men with symptomatic gonococcal urethritis"],"prefix":"10.1136","volume":"97","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0955-6307","authenticated-orcid":false,"given":"Daniel","family":"Richardson","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5534-8392","authenticated-orcid":false,"given":"David A","family":"Lewis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Neisha J","family":"Jeoffreys","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Deborah L","family":"Couldwell","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2020,9,10]]},"reference":[{"key":"2024092104001020000_97.5.363.1","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jix145"},{"key":"2024092104001020000_97.5.363.2","doi-asserted-by":"publisher","DOI":"10.1136\/sextrans-2017-053480"},{"key":"2024092104001020000_97.5.363.3","doi-asserted-by":"publisher","DOI":"10.1093\/ije\/dyv194"},{"key":"2024092104001020000_97.5.363.4","doi-asserted-by":"publisher","DOI":"10.1136\/sextrans-2017-053384"},{"key":"2024092104001020000_97.5.363.5","doi-asserted-by":"crossref","first-page":"e01125","DOI":"10.1128\/JCM.01125-19","article-title":"Molecular testing for Mycoplasma genitalium in the United States: results from the Ames prospective multicenter clinical study","volume":"57","author":"Gaydos","year":"2019","journal-title":"J Clin Microbiol"},{"key":"2024092104001020000_97.5.363.6","doi-asserted-by":"publisher","DOI":"10.1136\/sti.2006.022970"},{"key":"2024092104001020000_97.5.363.7","doi-asserted-by":"publisher","DOI":"10.1177\/0956462419825948"},{"key":"2024092104001020000_97.5.363.8","unstructured":"ASHA . Australia STI management guidelines for use in primary care: Mycoplasma genitalium. Available: http:\/\/www.sti.guidelines.org.au\/sexually-transmissible-infections\/mycoplasma-genitalium#clinical-presentation [Accessed 11 Feb 2020]."},{"key":"2024092104001020000_97.5.363.9","unstructured":"Centers for Disease Control and Prevention . Sexually transmitted diseases treatment guidelines: Mycoplasma genitalium, 2015. Available: https:\/\/www.cdc.gov\/std\/tg2015\/emerging.htm#myco [Accessed 11 Feb 2020]."},{"key":"2024092104001020000_97.5.363.10","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.13849"},{"key":"2024092104001020000_97.5.363.11","doi-asserted-by":"publisher","DOI":"10.1177\/0956462419886775"},{"key":"2024092104001020000_97.5.363.12","doi-asserted-by":"publisher","DOI":"10.1071\/SH19121"},{"key":"2024092104001020000_97.5.363.13","doi-asserted-by":"publisher","DOI":"10.1071\/SH19016"},{"key":"2024092104001020000_97.5.363.14","doi-asserted-by":"publisher","DOI":"10.1071\/SH19034"},{"key":"2024092104001020000_97.5.363.15","doi-asserted-by":"publisher","DOI":"10.1136\/sextrans-2019-054058"},{"key":"2024092104001020000_97.5.363.16","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0196217"},{"key":"2024092104001020000_97.5.363.17","doi-asserted-by":"publisher","DOI":"10.1177\/0956462416630675"},{"key":"2024092104001020000_97.5.363.18","doi-asserted-by":"publisher","DOI":"10.1136\/sextrans-2018-053848"},{"key":"2024092104001020000_97.5.363.19","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.42.2.683-692.2004"},{"key":"2024092104001020000_97.5.363.20","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmi.2017.02.020"},{"key":"2024092104001020000_97.5.363.21","doi-asserted-by":"publisher","DOI":"10.1136\/sextrans-2016-053060"},{"key":"2024092104001020000_97.5.363.22","doi-asserted-by":"publisher","DOI":"10.1086\/593188"},{"key":"2024092104001020000_97.5.363.23","doi-asserted-by":"publisher","DOI":"10.1097\/OLQ.0000000000000793"},{"key":"2024092104001020000_97.5.363.24","doi-asserted-by":"publisher","DOI":"10.1136\/sti.2009.038190"},{"key":"2024092104001020000_97.5.363.25","doi-asserted-by":"publisher","DOI":"10.1016\/j.jadohealth.2006.12.005"},{"key":"2024092104001020000_97.5.363.26","doi-asserted-by":"publisher","DOI":"10.1097\/OLQ.0000000000001009"}],"container-title":["Sexually Transmitted Infections"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/sextrans-2020-054529","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,9,21]],"date-time":"2024-09-21T11:00:56Z","timestamp":1726916456000},"score":1,"resource":{"primary":{"URL":"https:\/\/sti.bmj.com\/lookup\/doi\/10.1136\/sextrans-2020-054529"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,9,10]]},"references-count":26,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2021,7,19]]},"published-print":{"date-parts":[[2021,8]]}},"alternative-id":["10.1136\/sextrans-2020-054529"],"URL":"https:\/\/doi.org\/10.1136\/sextrans-2020-054529","relation":{},"ISSN":["1368-4973","1472-3263"],"issn-type":[{"value":"1368-4973","type":"print"},{"value":"1472-3263","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,9,10]]}}}