{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,29]],"date-time":"2025-12-29T11:09:34Z","timestamp":1767006574346,"version":"3.37.3"},"reference-count":5,"publisher":"BMJ","issue":"5","license":[{"start":{"date-parts":[[2020,9,2]],"date-time":"2020-09-02T00:00:00Z","timestamp":1599004800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/bmj.com\/coronavirus\/usage"}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["Sex Transm Infect"],"accepted":{"date-parts":[[2020,8,9]]},"published-print":{"date-parts":[[2021,8]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>To report on the clinical characteristics and outcome of 18 people living with HIV (PLWH) hospitalised with SARS-CoV-2 infection in a London teaching hospital.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The hospital notes of 18 PLWH hospitalised with SARS-CoV-2 infection were retrospectively reviewed alongside data concerning their HIV demographics from an established HIV Database.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The majority (16\/18) had positive PCR swabs for SARS-CoV-2, and two had negative swabs but typical COVID-19 imaging and history. Most were male (14\/18, 78%), median age 63 years (range 47\u201377 years). Two-thirds were migrants, nine (50%) of Black, Asian and minority ethnicity (BAME). All were diagnosed with HIV for many years (range 8\u201331 years), and all had an undetectable HIV viral load (&lt;40 copies\/mL). The median CD4 prior to admission was 439 (IQR 239\u2013651), and 10\/16 (63%) had a CD4 nadir below 200 cells\/mm<jats:sup>3<\/jats:sup>. Almost all (17\/18) had been diagnosed with at least one comorbidity associated with SARS-CoV-2 prior to admission. 3\/18 patients died. None received mechanical ventilation. Hospital stay and clinical course did not appear prolonged (median 9 days).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Our data suggest that PLWH may not necessarily have prolonged or complex admissions to hospital when compared with the general hospital and national population admitted with COVID-19. Many had low nadir CD4 counts and potentially impaired functional immune restoration. The PLWH group was younger than generally reported for COVID-19, and the majority were male with multiple complex comorbidities. These patients had frequent contact with hospital settings increasing potential for nosocomial acquisition and increased risk of severe COVID-19.<\/jats:p><\/jats:sec>","DOI":"10.1136\/sextrans-2020-054660","type":"journal-article","created":{"date-parts":[[2020,9,2]],"date-time":"2020-09-02T21:20:44Z","timestamp":1599081644000},"page":"392-393","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":5,"title":["Descriptive account of 18 adults with known HIV infection hospitalised with SARS-CoV-2 infection"],"prefix":"10.1136","volume":"97","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2381-2947","authenticated-orcid":false,"given":"Sara","family":"Madge","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1914-4891","authenticated-orcid":false,"given":"Tristan J","family":"Barber","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alan","family":"Hunter","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sanjay","family":"Bhagani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marc","family":"Lipman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fiona","family":"Burns","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2020,9,2]]},"reference":[{"key":"2024092104001373000_97.5.392.1","unstructured":"BHIVA . BHIVA, DAIG, EACS, GESIDA & Polish Scientific AIDS Society Statement on risk of COVID-19 for people living with HIV (PLWH), 2020."},{"key":"2024092104001373000_97.5.392.2","doi-asserted-by":"crossref","DOI":"10.1007\/s15010-020-01438-z","article-title":"COVID-19 in people living with human immunodeficiency virus: a case series of 33 patients","author":"H\u00e4rter","year":"2020","journal-title":"Infection"},{"key":"2024092104001373000_97.5.392.3","article-title":"Hospitalized patients with COVID-19 and HIV: a case series","author":"Childs","year":"2020","journal-title":"Clin Infect Dis"},{"key":"2024092104001373000_97.5.392.4","doi-asserted-by":"publisher","DOI":"10.1186\/s12916-020-01665-z"},{"key":"2024092104001373000_97.5.392.5","unstructured":"Hall M , Pritchard M , Dankwa E . ISARIC COVID-19 clinical data report: 8 June 2020. medRxiv."}],"container-title":["Sexually Transmitted Infections"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/sextrans-2020-054660","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,9,21]],"date-time":"2024-09-21T11:00:43Z","timestamp":1726916443000},"score":1,"resource":{"primary":{"URL":"https:\/\/sti.bmj.com\/lookup\/doi\/10.1136\/sextrans-2020-054660"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,9,2]]},"references-count":5,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2021,7,19]]},"published-print":{"date-parts":[[2021,8]]}},"alternative-id":["10.1136\/sextrans-2020-054660"],"URL":"https:\/\/doi.org\/10.1136\/sextrans-2020-054660","relation":{},"ISSN":["1368-4973","1472-3263"],"issn-type":[{"type":"print","value":"1368-4973"},{"type":"electronic","value":"1472-3263"}],"subject":[],"published":{"date-parts":[[2020,9,2]]}}}