{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,6]],"date-time":"2026-07-06T15:21:09Z","timestamp":1783351269037,"version":"3.54.6"},"reference-count":10,"publisher":"BMJ","issue":"6","funder":[{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program","doi-asserted-by":"crossref","award":["2017YFE0103800"],"award-info":[{"award-number":["2017YFE0103800"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"crossref"}]},{"name":"the i Guardian Platform of the People's Medical Publishing House","award":["n\/a"],"award-info":[{"award-number":["n\/a"]}]},{"name":"Australian National Health and Medical Research Council (NHMRC) Emerging Leadership Investigator Grant","award":["GNT1172873"],"award-info":[{"award-number":["GNT1172873"]}]},{"DOI":"10.13039\/501100018537","name":"National Science and Technology Major Project","doi-asserted-by":"crossref","award":["2018ZX10721102-003004"],"award-info":[{"award-number":["2018ZX10721102-003004"]}],"id":[{"id":"10.13039\/501100018537","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["Sex Transm Infect"],"accepted":{"date-parts":[[2020,11,29]]},"published-print":{"date-parts":[[2021,9]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>To examine the feasibility of non-occupational postexposure prophylaxis (nPEP) as a national strategy for HIV prevention in China, we investigated nPEP usage and related sociodemographic and behavioural factors among five key populations at high risk of contracting HIV.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We conducted a cross-sectional study among five key populations from November 2018 to September 2019 in China using convenience sampling to recruit participants aged \u226518 years, self-reporting HIV status as either negative or unknown and providing written informed consent. Univariable and multivariable logistic regression models were fitted.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Our analysis included data from 2022 participants with a mean age of 35 years (SD=11.62). Only 57 (2.82%) participants had ever used nPEP. Sociodemographic and behavioural factors related to nPEP usage included populations (p&lt;0.0001), age (p&lt;0.05), education (p&lt;0.05), nPEP knowledge (p&lt;0.01), receiving conventional HIV prevention services (p&lt;0.05) and HIV testing (p&lt;0.05). A significant percentage (26%) of nPEP users used nPEP medication more than once. Challenges and concerns, such as multiple use of nPEP and syndemic conditions, were emerging.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Key populations in China had low nPEP usage rates. Female sex workers, people who use drugs, older and illiterate individuals with poor nPEP knowledge, not using HIV prevention services or never tested for HIV should be emphasised. Implementing nPEP services would be an important way to access high-risk individuals for intensive and tailored HIV prevention and intervention. Challenges of providing nPEP services and future study foci are highlighted.<\/jats:p><\/jats:sec>","DOI":"10.1136\/sextrans-2020-054791","type":"journal-article","created":{"date-parts":[[2021,1,4]],"date-time":"2021-01-04T18:27:25Z","timestamp":1609784845000},"page":"411-413","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":10,"title":["HIV non-occupational postexposure prophylaxis (nPEP) usage among five key populations in China"],"prefix":"10.1136","volume":"97","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0318-9921","authenticated-orcid":false,"given":"Haochu","family":"Li","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ran","family":"Wei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7822-3971","authenticated-orcid":false,"given":"Eduardo","family":"Piqueiras","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1766-0657","authenticated-orcid":false,"given":"Eric P F","family":"Chow","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kedi","family":"Jiao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Taylor","family":"Lewis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2021,1,4]]},"reference":[{"key":"2024092104100708000_97.6.411.1","unstructured":"UNAIDS . China country fact Sheet\u2014Global AIDS update 2019. Geneva: UNAIDS, 2019. Available: https:\/\/www.unaids.org\/en\/regionscountries\/countries\/china [Accessed Jan 8, 2020]."},{"key":"2024092104100708000_97.6.411.2","doi-asserted-by":"crossref","unstructured":"Wang Z , Yuan T , Fan S , et al . Non-Occupational HIV post-exposure prophylaxis among men who have sex with men: a systematic review and meta-analysis of global data. Lancet HIV 2019;71.doi:10.2139\/ssrn.3501040","DOI":"10.2139\/ssrn.3501040"},{"key":"2024092104100708000_97.6.411.3","first-page":"1","article-title":"Socioeconomic disparity of immunologic outcome among people living with HIV in Guangxi, China","author":"Yang","year":"2020","journal-title":"AIDS Care"},{"key":"2024092104100708000_97.6.411.4","doi-asserted-by":"publisher","DOI":"10.1136\/sti.2008.033662"},{"key":"2024092104100708000_97.6.411.5","doi-asserted-by":"publisher","DOI":"10.1097\/QAD.0b013e32832c1776"},{"key":"2024092104100708000_97.6.411.6","doi-asserted-by":"publisher","DOI":"10.1186\/s12879-019-4559-1"},{"key":"2024092104100708000_97.6.411.7","doi-asserted-by":"publisher","DOI":"10.7448\/IAS.19.1.20038"},{"key":"2024092104100708000_97.6.411.8","doi-asserted-by":"publisher","DOI":"10.1097\/QAD.0000000000001145"},{"key":"2024092104100708000_97.6.411.9","doi-asserted-by":"publisher","DOI":"10.1097\/QAD.0000000000000505"},{"key":"2024092104100708000_97.6.411.10","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-1293.2010.00826.x"}],"container-title":["Sexually Transmitted Infections"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/sextrans-2020-054791","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,9,21]],"date-time":"2024-09-21T11:11:06Z","timestamp":1726917066000},"score":1,"resource":{"primary":{"URL":"https:\/\/sti.bmj.com\/lookup\/doi\/10.1136\/sextrans-2020-054791"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,1,4]]},"references-count":10,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2021,8,17]]},"published-print":{"date-parts":[[2021,9]]}},"alternative-id":["10.1136\/sextrans-2020-054791"],"URL":"https:\/\/doi.org\/10.1136\/sextrans-2020-054791","relation":{},"ISSN":["1368-4973","1472-3263"],"issn-type":[{"value":"1368-4973","type":"print"},{"value":"1472-3263","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,1,4]]}}}