{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T01:00:18Z","timestamp":1793754018973,"version":"4.6.1"},"reference-count":32,"publisher":"BMJ","issue":"4","license":[{"start":{"date-parts":[[2025,1,20]],"date-time":"2025-01-20T00:00:00Z","timestamp":1737331200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"Aidsfonds","award":["2014037"],"award-info":[{"award-number":["2014037"]}]}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["Sex Transm Infect"],"accepted":{"date-parts":[[2024,11,29]]},"published-print":{"date-parts":[[2025,6]]},"abstract":"<jats:p>\n                    <jats:bold>Objectives<\/jats:bold>\n                    Men who have sex with men (MSM) are disproportionally affected by HIV in the Netherlands. Partner notification (PN) is an important element in controlling the transmission of sexually transmitted infections (STIs) and HIV. We investigated the effects of improving PN on the transmission of HIV and\n                    <jats:italic>Neisseria gonorrhoeae<\/jats:italic>\n                    (NG) among MSM in the Netherlands.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Methods<\/jats:bold>\n                    We developed an agent-based model that describes the transmission of HIV and NG among MSM. In the baseline scenario, 14.3% and 29.8% of casual and steady partners of the index case get notified and tested for HIV\/STI after 3\u2009weeks (percentage notified and tested (PNT)). We examined the following scenarios: (1) increase PNT to 41% for both partner types; (2) decrease the time between the index and the partners tested to 1\u2009week and (3) combine scenarios 1 and 2. Effects are expressed as cumulative change from the baseline simulation over 15 years.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Results<\/jats:bold>\n                    Increasing PNT could lead to a decrease in gonorrhoea cases of 45% (IQR 39.9% to 49.9%), with an increase in the number of HIV\/STI tests of 4.4% (IQR 1.6% to 7.3%), but no change in HIV infections (\u22125.4%; IQR \u221221% to 7.9%). Decreasing the time between tests could lead to a change in new NG infections of \u221214.2% (IQR \u221217.2% to \u221210%), no change in HIV infections (8.2%; IQR \u22121.3% to 20%) or in the number of HIV\/STI tests performed (\u22120.4%; IQR \u22121.5 to 0.6%). Scenario 3 led to a change in NG infections of \u221256.8% (IQR \u221263.8% to \u221247.4%), no change in HIV infections (11.5%; IQR \u221211.1% to 33.9%) or in the number of HIV\/STI tests (\u22120.5%; IQR: \u22124.9% to 4.3%).\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Conclusions<\/jats:bold>\n                    Increasing the percentage of sexual partners notified and tested for HIV\/STI may have only a small effect on HIV but could reduce the number of new NG infections substantially. However, it could lead to an increase in the number of HIV\/STI tests performed.\n                  <\/jats:p>","DOI":"10.1136\/sextrans-2023-055772","type":"journal-article","created":{"date-parts":[[2025,1,20]],"date-time":"2025-01-20T13:20:13Z","timestamp":1737379213000},"page":"236-241","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":3,"title":["Effects of improved partner notification on the transmission of HIV and\n                    <i>N. gonorrhoea<\/i>\n                    among men who have sex with men: a modelling study"],"prefix":"10.1136","volume":"101","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5524-1069","authenticated-orcid":false,"given":"Maarten","family":"Reitsema","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacco","family":"Wallinga","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Birgit H B","family":"van Benthem","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eline L M","family":"Op de Coul","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6656-0516","authenticated-orcid":false,"given":"Ard","family":"Van Sighem","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maarten","family":"Schim van der Loeff","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5257-4503","authenticated-orcid":false,"given":"Maria","family":"Xiridou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2025,1,20]]},"reference":[{"key":"2025051910100616000_101.4.236.1","unstructured":"Sighem AI , Wit F , Boyd A , et al . Monitoring report 2023. Amsterdam Stichting hiv monitoring; 2023."},{"key":"2025051910100616000_101.4.236.2","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(14)70847-3"},{"key":"2025051910100616000_101.4.236.3","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(15)00056-2"},{"key":"2025051910100616000_101.4.236.4","doi-asserted-by":"publisher","DOI":"10.1016\/S2352-3018(19)30136-5"},{"key":"2025051910100616000_101.4.236.5","unstructured":"Wees D , Visser M , Aar F , et al . Sexually transmitted infections in the netherlands in 2021. RIVM rapport 2022-0023; 2022."},{"key":"2025051910100616000_101.4.236.6","doi-asserted-by":"publisher","DOI":"10.1136\/sextrans-2020-054551"},{"key":"2025051910100616000_101.4.236.7","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1105243"},{"key":"2025051910100616000_101.4.236.8","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1506816"},{"key":"2025051910100616000_101.4.236.9","doi-asserted-by":"publisher","DOI":"10.1136\/sextrans-2013-051254"},{"key":"2025051910100616000_101.4.236.10","doi-asserted-by":"publisher","DOI":"10.1097\/QAD.0000000000002199"},{"key":"2025051910100616000_101.4.236.11","doi-asserted-by":"publisher","DOI":"10.1136\/sextrans-2018-053943"},{"key":"2025051910100616000_101.4.236.12","doi-asserted-by":"publisher","DOI":"10.1097\/QAD.0000000000002469"},{"key":"2025051910100616000_101.4.236.13","unstructured":"Visser M , Aar F , Coul E , et al . Sexually transmitted infections in the netherlands in 2017. 2018."},{"key":"2025051910100616000_101.4.236.14","unstructured":"Slurink I , Aar F , Coul E , et al . Sexually transmitted infections in the netherlands in 2018. 2019."},{"key":"2025051910100616000_101.4.236.15","unstructured":"Staritsky L , Aar F , Visser M , et al . Sexually transmitted infections in the netherlands in 2019. 2020."},{"key":"2025051910100616000_101.4.236.16","unstructured":"Sighem AIW , Smit C , Matser A , et al . Monitoring report 2021. In: Human Immunodeficiency Virus (HIV) Infection in the Netherlands. Amsterdam: Stichting hiv monitoring, 2021."},{"key":"2025051910100616000_101.4.236.17","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pcbi.1002803","article-title":"Approximate Bayesian computation","volume":"9","author":"Sunn\u00e5ker","year":"2013","journal-title":"PLoS Comput Biol"},{"key":"2025051910100616000_101.4.236.18","doi-asserted-by":"crossref","DOI":"10.1186\/1471-2334-12-114","article-title":"Current practices of partner notification among MSM with HIV, gonorrhoea and syphilis in the Netherlands: an urgent need for improvement","volume":"12","author":"van Aar","year":"2012","journal-title":"BMC Infect Dis"},{"key":"2025051910100616000_101.4.236.19","unstructured":"G\u00f6tz HSR , Bos H . Draaiboek Soa en hiv partnermanagement, 2018. 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Bilthoven: Rijksinstituut voor Volksgezondheid en Milieu RIVM, 2024."},{"key":"2025051910100616000_101.4.236.22","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0142576","article-title":"Partner Notification for Reduction of HIV-1 Transmission and Related Costs among Men Who Have Sex with Men: A Mathematical Modeling Study","volume":"10","author":"Nichols","year":"2015","journal-title":"PLoS One"},{"key":"2025051910100616000_101.4.236.23","doi-asserted-by":"publisher","DOI":"10.3310\/hta18520"},{"key":"2025051910100616000_101.4.236.24","first-page":"222","article-title":"Contact tracing - Old models and new challenges","volume":"6","author":"M\u00fcller","year":"2021","journal-title":"Infect Dis Model"},{"key":"2025051910100616000_101.4.236.25","doi-asserted-by":"publisher","DOI":"10.1098\/rspb.2003.2554"},{"key":"2025051910100616000_101.4.236.26","first-page":"801","article-title":"The Role of HIV Partner Services in the Modern Biomedical HIV Prevention Era: A Network Modeling Study","volume":"49","author":"Jenness","year":"2022","journal-title":"Sex Transm Dis"},{"key":"2025051910100616000_101.4.236.27","doi-asserted-by":"publisher","DOI":"10.1136\/sextrans-2021-055220"},{"key":"2025051910100616000_101.4.236.28","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciab680"},{"key":"2025051910100616000_101.4.236.29","doi-asserted-by":"publisher","DOI":"10.1136\/sextrans-2012-050674"},{"key":"2025051910100616000_101.4.236.30","doi-asserted-by":"crossref","DOI":"10.1093\/jtm\/taz101","article-title":"Antimicrobial resistance in sexually transmitted infections","volume":"27","author":"Tien","year":"2020","journal-title":"J Travel Med"},{"key":"2025051910100616000_101.4.236.31","doi-asserted-by":"crossref","DOI":"10.2807\/1560-7917.ES.2022.27.34.2200081","article-title":"Trends and regional variations of gonococcal antimicrobial resistance in the Netherlands, 2013 to 2019","volume":"27","author":"Visser","year":"2022","journal-title":"Euro Surveill"},{"key":"2025051910100616000_101.4.236.32","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2334-10-1"}],"container-title":["Sexually Transmitted Infections"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/sextrans-2023-055772","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,21]],"date-time":"2025-05-21T22:01:47Z","timestamp":1747864907000},"score":1,"resource":{"primary":{"URL":"https:\/\/sti.bmj.com\/lookup\/doi\/10.1136\/sextrans-2023-055772"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1,20]]},"references-count":32,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2025,5,19]]},"published-print":{"date-parts":[[2025,6]]}},"alternative-id":["10.1136\/sextrans-2023-055772"],"URL":"https:\/\/doi.org\/10.1136\/sextrans-2023-055772","relation":{"has-preprint":[{"id-type":"doi","id":"10.1101\/2024.08.28.24312692","asserted-by":"object"}]},"ISSN":["1368-4973","1472-3263"],"issn-type":[{"value":"1368-4973","type":"print"},{"value":"1472-3263","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,1,20]]}}}