{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,3]],"date-time":"2026-03-03T19:10:16Z","timestamp":1772565016726,"version":"3.50.1"},"reference-count":11,"publisher":"BMJ","funder":[{"DOI":"10.13039\/100000060","name":"National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","award":["R01AI149339"],"award-info":[{"award-number":["R01AI149339"]}],"id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["Sex Transm Infect"],"accepted":{"date-parts":[[2026,1,6]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>Sexually transmitted infections (STIs) are common in pregnant women. Effective partner treatment of women with an STI is essential to prevent reinfection. We evaluated the impact of partner notification and treatment based on the occurrence of repeat STIs in pregnant women in South Africa.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      We used data from one of the intervention arms in a randomised clinical trial of STI diagnostic screening strategies in pregnancy. In this cohort, women were tested at their first antenatal care visit (&lt;27\u2009weeks gestational age) using onsite Xpert test assays (Cepheid, Sunnyvale, California, USA) for\n                      <jats:italic>Chlamydia trachomatis<\/jats:italic>\n                      ,\n                      <jats:italic>Neisseria gonorrhoeae<\/jats:italic>\n                      and\n                      <jats:italic>Trichomonas vaginalis<\/jats:italic>\n                      . Women with a positive STI result received pathogen-directed treatment, partner notification slips, and a test-of-cure visit was scheduled 21\u201335\u2009days post-treatment. At the test of cure visit, sexual behaviour and partner treatment data were collected, and STI testing was repeated. Cure was defined as a negative result at the test-of-cure visit.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Of 754 women tested, 193 (26%) tested positive for an STI and 183 (95%) received pathogen-directed treatment. A test-of-cure visit was attended by 108\/183 (59%) women within the time window. Of those, 19\/108 (18%) had a positive repeat STI result. Most women attending the test-of-cure visit (95%; 103\/108) reported disclosure of their STI to their partner; however, only 44% (48\/108) reported that their partner received treatment. Among those who reported partner treatment, the repeat STI positivity was 4% versus 27% in those with reported untreated partners (risk ratio 0.15 with 95% CI 0.03 to 0.7).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Reported partner treatment reduced the likelihood of a repeat positive test result in pregnant women. Strengthening partner notification and treatment is essential to prevent reinfection.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1136\/sextrans-2025-056758","type":"journal-article","created":{"date-parts":[[2026,2,6]],"date-time":"2026-02-06T18:20:22Z","timestamp":1770402022000},"page":"sextrans-2025-056758","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Association between partner treatment and repeat sexually transmitted infections positivity in pregnant women in East London, South Africa"],"prefix":"10.1136","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2795-0343","authenticated-orcid":false,"given":"Mildred Mandisa","family":"Mdingi","sequence":"first","affiliation":[{"name":"Research Unit, Foundation for Professional Development, East London, South Africa"},{"name":"Medical Microbiology, University of Pretoria, Hatfield Campus, Pretoria, GP, South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ranjana M S","family":"Gigi","sequence":"additional","affiliation":[{"name":"Research Unit, Foundation for Professional Development, East London, South Africa"},{"name":"Department of Social and Preventive Medicine, University of Bern, Bern, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chibuzor M","family":"Babalola","sequence":"additional","affiliation":[{"name":"University of Southern California Keck School of Medicine, Los Angeles, California, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christopher","family":"Taylor","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Immunology and Parasitology, Louisiana State University Health Sciences Center Department of Microbiology and Immunology, Shreveport, Louisiana, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4005-3858","authenticated-orcid":false,"given":"Christina A","family":"Muzny","sequence":"additional","affiliation":[{"name":"Medicine\/ID, University of Alabama at Birmingham, Birmingham, Alabama, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2691-982X","authenticated-orcid":false,"given":"Andrew","family":"Medina Marino","sequence":"additional","affiliation":[{"name":"University of Pennsylvania Department of Psychiatry, Philadelphia, Pennsylvania, USA"},{"name":"Desmond Tutu Health Foundation, Cape Town, WC, South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeffrey D","family":"Klausner","sequence":"additional","affiliation":[{"name":"University of Southern California Keck School of Medicine, Los Angeles, California, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2124-7275","authenticated-orcid":false,"given":"Remco P H","family":"Peters","sequence":"additional","affiliation":[{"name":"Research Unit, Foundation for Professional Development, East London, South Africa"},{"name":"Medical Microbiology, University of Pretoria, Hatfield Campus, Pretoria, GP, South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2026,2,6]]},"reference":[{"key":"2026030310201601000_sextrans-2025-056758v2.1","unstructured":"World Health Organization . Geneva. Global prevalence and incidence of selected curable sexually transmitted infections: overview and estimates: WHO\/HIV_AIDS\/2001.02, WHO\/CDS\/CSR\/EDC. 2001."},{"key":"2026030310201601000_sextrans-2025-056758v2.2","doi-asserted-by":"publisher","DOI":"10.1136\/sextrans-2020-054631"},{"key":"2026030310201601000_sextrans-2025-056758v2.3","article-title":"Sexually transmitted pathogens in asymptomatic women at Rethabile clinic, Limpopo, South Africa","volume":"39","author":"Mukavhanyedzi","year":"2024","journal-title":"S Afr J Infect Dis"},{"key":"2026030310201601000_sextrans-2025-056758v2.4","doi-asserted-by":"publisher","DOI":"10.1111\/1471-0528.16617"},{"key":"2026030310201601000_sextrans-2025-056758v2.5","article-title":"Erratum: Southern African HIV Clinicians Society 2022 guideline for the management of sexually transmitted infections: Moving towards best practice","volume":"23","author":"Peters","year":"2022","journal-title":"South Afr J HIV Med"},{"key":"2026030310201601000_sextrans-2025-056758v2.6","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1177\/0956462419898612","article-title":"Persistent Chlamydia trachomatis, Neisseria gonorrhoeae or Trichomonas vaginalis positivity after treatment among human immunodeficiency virus-infected pregnant women, South Africa","volume":"31","author":"Medina-Marino","year":"2020","journal-title":"Int J STD AIDS"},{"key":"2026030310201601000_sextrans-2025-056758v2.7","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1186\/s13063-022-06400-y","article-title":"Sexually transmitted infection screening to prevent adverse birth and newborn outcomes: study protocol for a randomized-controlled hybrid-effectiveness trial","volume":"23","author":"Medina-Marino","year":"2022","journal-title":"Trials"},{"key":"2026030310201601000_sextrans-2025-056758v2.8","doi-asserted-by":"crossref","first-page":"786","DOI":"10.1177\/09564624251347484","article-title":"Prevalence, symptomology, and correlates of curable sexually transmitted infections among pregnant women in Eastern Cape, South Africa","volume":"36","author":"Shaetonhodi","year":"2025","journal-title":"Int J STD AIDS"},{"key":"2026030310201601000_sextrans-2025-056758v2.9","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1097\/OLQ.0000000000001725","article-title":"High Cure Rate Among Pregnant Women in a Chlamydia trachomatis and Neisseria gonorrhoeae Testing and Treatment Intervention Study in Gaborone, Botswana","volume":"50","author":"Mussa","year":"2023","journal-title":"Sex Transm Dis"},{"key":"2026030310201601000_sextrans-2025-056758v2.10","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1097\/OLQ.0000000000000355","article-title":"Patient-Delivered Partner Treatment for Chlamydia, Gonorrhea, and Trichomonas Infection Among Pregnant and Postpartum Women in Kenya","volume":"42","author":"Unger","year":"2015","journal-title":"Sex Transm Dis"},{"key":"2026030310201601000_sextrans-2025-056758v2.11","doi-asserted-by":"crossref","first-page":"e2097","DOI":"10.1016\/S2214-109X(25)00306-7","article-title":"Financial incentives to improve uptake of partner treatment for sexually transmitted infections in antenatal care: a cluster randomised trial in Zimbabwe","volume":"13","author":"Martin","year":"2025","journal-title":"Lancet Glob Health"}],"container-title":["Sexually Transmitted Infections"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/sextrans-2025-056758","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,3]],"date-time":"2026-03-03T18:20:26Z","timestamp":1772562026000},"score":1,"resource":{"primary":{"URL":"https:\/\/sti.bmj.com\/lookup\/doi\/10.1136\/sextrans-2025-056758"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2,6]]},"references-count":11,"alternative-id":["10.1136\/sextrans-2025-056758"],"URL":"https:\/\/doi.org\/10.1136\/sextrans-2025-056758","relation":{},"ISSN":["1368-4973","1472-3263"],"issn-type":[{"value":"1368-4973","type":"print"},{"value":"1472-3263","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,2,6]]}}}