{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T04:05:22Z","timestamp":1777953922664,"version":"3.51.4"},"reference-count":10,"publisher":"BMJ","license":[{"start":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T00:00:00Z","timestamp":1777852800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/100014302","name":"Elton John AIDS Foundation","doi-asserted-by":"publisher","award":["NA"],"award-info":[{"award-number":["NA"]}],"id":[{"id":"10.13039\/100014302","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["Sex Transm Infect"],"accepted":{"date-parts":[[2026,3,29]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>We evaluated the uptake of an at-home syphilis testing option through TakeMeHome, a free HIV\/STI self-testing programme, and assessed the correlates of selecting the new testing option in this cross-sectional evaluation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Data consisted of self-test orders placed between January and July 2025 in jurisdictions that introduced an at-home syphilis self-testing option through TakeMeHome and previously did not offer STI testing through the programme. Poisson regression models with robust standard errors were used to estimate the associations between participant race\/ethnicity, gender identity, last HIV\/STI test date, status as a previous TakeMeHome tester, and age and the outcome of ordering an add-on at-home syphilis test.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>In jurisdictions that did not previously offer an STI testing option, 1234 at-home tests were ordered over the follow-up period, with 907 (74%) orders for an at-home HIV test with an at-home syphilis test. Cisgender women were more likely to be interested in and eligible for the syphilis test compared with cisgender men, after adjustment for race\/ethnicity, last HIV\/STI test date, being a previous TakeMeHome tester, jurisdiction and age (adjusted PR: 1.22, 95%\u2009CI 1.13 to 1.33, p&lt;0.0005).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>There was high interest in and uptake of the new at-home syphilis testing option in jurisdictions that previously did not offer at-home STI testing through TakeMeHome.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1136\/sextrans-2025-056883","type":"journal-article","created":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T17:20:51Z","timestamp":1777915251000},"page":"sextrans-2025-056883","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Increasing access to STI testing through addition of at-home syphilis testing to the TakeMeHome self-testing programme in Los Angeles County and North Carolina"],"prefix":"10.1136","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0541-3854","authenticated-orcid":false,"given":"Shalika","family":"Gupta","sequence":"first","affiliation":[{"name":"Springboard HealthLab, Richmond, California, USA"},{"name":"BHOC, Richmond, California, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Melissa","family":"Papp-Green","sequence":"additional","affiliation":[{"name":"Los Angeles County Department of Public Health Division of HIV and STD Programs, Los Angeles, California, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marti","family":"Eisenberg","sequence":"additional","affiliation":[{"name":"North Carolina Department of Health and Human Services, Raleigh, North Carolina, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jenny","family":"Mahn","sequence":"additional","affiliation":[{"name":"NASTAD, Washington, District of Columbia, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jennifer","family":"Hecht","sequence":"additional","affiliation":[{"name":"Springboard HealthLab, Richmond, California, USA"},{"name":"BHOC, Richmond, California, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2026,5,4]]},"reference":[{"key":"2026050410203003000_sextrans-2025-056883v1.1","doi-asserted-by":"crossref","first-page":"15","DOI":"10.3390\/jcm14155308","article-title":"The Epidemiology of Syphilis Worldwide in the Last Decade","volume":"14","author":"Rosset","year":"2025","journal-title":"J Clin Med"},{"key":"2026050410203003000_sextrans-2025-056883v1.2","unstructured":"Centers for Disease Control and Prevention . Sexually Transmitted Infections Surveillance 2024 (Provisional). U.S. Department of Health and Human Services; 2025. Available: https:\/\/www.cdc.gov\/sti-statistics\/annual\/index.html"},{"key":"2026050410203003000_sextrans-2025-056883v1.3","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2016.7073"},{"key":"2026050410203003000_sextrans-2025-056883v1.4","doi-asserted-by":"crossref","DOI":"10.1177\/1178633719883282","article-title":"Resurgence of Syphilis in the United States: An Assessment of Contributing Factors","volume":"12","author":"Schmidt","year":"2019","journal-title":"Infect Dis (Auckl)"},{"key":"2026050410203003000_sextrans-2025-056883v1.5","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2014.13259"},{"key":"2026050410203003000_sextrans-2025-056883v1.6","doi-asserted-by":"crossref","DOI":"10.3390\/ijerph19053002","article-title":"HIV and STI Testing Preferences for Men Who Have Sex with Men in High-Income Countries: A Scoping Review","volume":"19","author":"Kularadhan","year":"2022","journal-title":"Int J Environ Res Public Health"},{"key":"2026050410203003000_sextrans-2025-056883v1.7","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm7038a2"},{"key":"2026050410203003000_sextrans-2025-056883v1.8","doi-asserted-by":"crossref","DOI":"10.1128\/jcm.00244-25","article-title":"Clinical development and performance of the First to Know Syphilis Self-Test for over-the-counter usage: a de novo rapid test for treponemal antibody","volume":"63","author":"Clark","year":"2025","journal-title":"J Clin Microbiol"},{"key":"2026050410203003000_sextrans-2025-056883v1.9","unstructured":"R Core Team . R: A Language and Environment for Statistical Computing. 2024 Available: https:\/\/www.R-project.org\/"},{"key":"2026050410203003000_sextrans-2025-056883v1.10","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1097\/OLQ.0000000000002250","article-title":"Pilot Study of Social Media Promotion of Home-Based Self-Testing for Syphilis","volume":"53","author":"Afana","year":"2026","journal-title":"Sex Transm Dis"}],"container-title":["Sexually Transmitted Infections"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/sextrans-2025-056883","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T17:20:53Z","timestamp":1777915253000},"score":1,"resource":{"primary":{"URL":"https:\/\/sti.bmj.com\/lookup\/doi\/10.1136\/sextrans-2025-056883"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5,4]]},"references-count":10,"alternative-id":["10.1136\/sextrans-2025-056883"],"URL":"https:\/\/doi.org\/10.1136\/sextrans-2025-056883","relation":{},"ISSN":["1368-4973","1472-3263"],"issn-type":[{"value":"1368-4973","type":"print"},{"value":"1472-3263","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,5,4]]}}}