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Ass., 97, 1579.","journal-title":"J. Amer. med. Ass"},{"key":"ref_23","first-page":"631","article-title":"Amer","volume":"20","author":"Wile, U.J.; Davenport, K.M.; Hand, E.A.","year":"1936","unstructured":"Wile, U. J., and Davenport, K. M. and Hand, E. A. (1936) Amer. J. Syph., 20, 631.","journal-title":"J. Syph"},{"key":"ref_24","article-title":"Penicillin used in the treatment of early syphilis","volume-title":"Harris report that after proving the usefulness of penicillin in treating syphilis in animals, they decided to study the drug's effects on early syphilis in human beings. Four men, each having a single penile ulceration, were given intramuscular injections of 25,000 units of penicillin at four-hourly intervals for eight days. Forty-eight injections were given and 1,200,000 units of the drug were used. The gluteal muscle was the site for the injections. During the first eight hours of treatment some clinical manifestations were observed, but the symptoms did not show any toxic response to the drug. A comprehensive routine of serodiagnostic tests was employed. After treatment, a long period of observation is essential. If the satisfactory results are confirmed, it may become necessary to change syphilis therapy using penicillin as the base. Venereal Disease Information","author":"Mahoney, J.F.; Arnold, R.C.; Ad","year":"1943","unstructured":"Penicillin used in the treatment of early syphilis J. F. Mahoney, R. C. Arnold and Ad. Harris report that after proving the usefulness of penicillin in treating syphilis in animals, they decided to study the drug's effects on early syphilis in human beings. Four men, each having a single penile ulceration, were given intramuscular injections of 25,000 units of penicillin at four-hourly intervals for eight days. Forty-eight injections were given and 1,200,000 units of the drug were used. The gluteal muscle was the site for the injections. During the first eight hours of treatment some clinical manifestations were observed, but the symptoms did not show any toxic response to the drug. A comprehensive routine of serodiagnostic tests was employed. After treatment, a long period of observation is essential. If the satisfactory results are confirmed, it may become necessary to change syphilis therapy using penicillin as the base.-Venereal Disease Information, Washington, December, 1943."}],"container-title":["Sexually Transmitted Infections"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/sti.20.1.37","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,9,26]],"date-time":"2020-09-26T10:31:50Z","timestamp":1601116310000},"score":1,"resource":{"primary":{"URL":"https:\/\/sti.bmj.com\/lookup\/doi\/10.1136\/sti.20.1.37"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1944,3,1]]},"references-count":24,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1944,3,1]]}},"URL":"https:\/\/doi.org\/10.1136\/sti.20.1.37","relation":{},"ISSN":["1368-4973"],"issn-type":[{"value":"1368-4973","type":"print"}],"subject":[],"published":{"date-parts":[[1944,3,1]]}}}