{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,2]],"date-time":"2025-02-02T18:40:18Z","timestamp":1738521618047,"version":"3.35.0"},"reference-count":23,"publisher":"BMJ","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sexually Transmitted Infections"],"published-print":{"date-parts":[[1970,4,1]]},"DOI":"10.1136\/sti.46.2.141","type":"journal-article","created":{"date-parts":[[2008,11,12]],"date-time":"2008-11-12T20:57:06Z","timestamp":1226523426000},"page":"141-144","source":"Crossref","is-referenced-by-count":0,"title":["Recent developments in the treatment of gonorrhoea."],"prefix":"10.1136","volume":"46","author":[{"given":"R R","family":"Willcox","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1136\/bmj.4.5632.681","volume":"4","author":"COBBOLD, R.J.C.; MORRISON, G.D.; WILLcox, R.R.","year":"1968","unstructured":"COBBOLD, R. J. C., MORRISON, G. D., and WILLcox, R. R. (1968). Brit. med. J., 4, 681.","journal-title":"Brit. med. J"},{"key":"ref_2","first-page":"161","article-title":"Brit. J7. vener","volume":"46","author":"SPITZER, R.J.; MORRISON, G.D.; WILLcox, R.R.","year":"1970","unstructured":"-, SPITZER, R. J., MORRISON, G. D., and WILLcox, R. R. (1970). Postgrad. med. J., 46, in press. CSoNKA, G. W., and KNIGHT, G. J. (1967) Brit. J7. vener. Dis., 43, 161.","journal-title":"Postgrad. med. J"},{"key":"ref_3","first-page":"70","volume":"34","author":"CURTIS, F.R.; WILKINSON, A.E.","year":"1958","unstructured":"CURTIS, F. R., and WILKINSON, A. E. (1958). Ibid., 34, 70.","journal-title":"Ibid"},{"key":"ref_4","first-page":"238","volume":"39","author":"JENSEN, P.E.; KVORNING, S.A.; N0RREDAm, K.","year":"1963","unstructured":"JENSEN, P. E., KVORNING, S. A., and N0RREDAm, K. (1963). Ibid., 39, 238.","journal-title":"Ibid"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1001\/jama.1967.03130190073009","volume":"202","author":"HOLMES, K.K.; JOHNSON, D.W.; FLOYD, T.M.; KVALE, P.A.","year":"1967","unstructured":"HOLMES, K. K., JOHNSON, D. W., FLOYD, T. M., and KVALE, P. A. (1967). J. Amer. med. Ass., 202, 467.","journal-title":"J. Amer. med. Ass"},{"key":"ref_6","first-page":"158","volume":"37","author":"LETCHNER, E.H.; NICOL, C.S.","year":"1961","unstructured":"LETCHNER, E. H., and NICOL, C. S. (1961). Brit. J3. vener. Dis., 37, 158.","journal-title":"Brit. J3. vener. Dis"},{"key":"ref_7","first-page":"1","volume":"42","author":"LOMHOLT, G.; BERG, 0","year":"1966","unstructured":"LOMHOLT, G., and BERG, 0. (1966). Ibid., 42, 1.","journal-title":"Ibid"},{"year":"1951","author":"MEADS, M.; KNIGHT, V.H.; IZLAR, H.L.","key":"ref_8","unstructured":"MEADS, M., KNIGHT, V. H., and IZLAR, H. L. (1951)."},{"key":"ref_9","first-page":"319","volume":"44","author":"MORRISON, G.D.; COBBOLD, R.J.C.; BOR, S.; SPITZER, R.J.; FOSTER, D.N.; WILLcox, R.R.","year":"1968","unstructured":"MORRISON, G. D., COBBOLD, R. J. C., BOR, S., SPITZER, R. J., FOSTER, D. N., and WILLcox, R. R. (1968). Brit. J. vener. Dis., 44, 319.","journal-title":"Brit. J. vener. Dis"},{"key":"ref_10","first-page":"105","volume":"39","author":"MORTON, R.S.","year":"1963","unstructured":"MORTON, R. S. (1963). Ibid., 39, 105.","journal-title":"Ibid"},{"key":"ref_11","first-page":"284","volume":"43","author":"ODEGAARD, K.; GJESSING, H.C.","year":"1967","unstructured":"ODEGAARD, K., and GJESSING, H. C. (1967). Ibid., 43, 284.","journal-title":"Ibid"},{"key":"ref_12","first-page":"140","volume":"44","author":"REYN, A.; BENTZON, M.W.","year":"1968","unstructured":"REYN, A., and BENTZON, M. W. (1968). Ibid., 44, 140.","journal-title":"Ibid"},{"key":"ref_13","first-page":"478","volume":"127","author":"SCHMIDT, H.; ROHOLT, K.","year":"1965","unstructured":"SCHMIDT, H., and ROHOLT, K. (1965). Ugeskr. Laeg., 127, 478.","journal-title":"Ugeskr. Laeg"},{"key":"ref_14","author":"SPITZER, R.J.; WILLcox, R.R.","year":"1968","unstructured":"SPITZER, R. J., and WILLcox, R. R. (1968). Acta derm.-","journal-title":"Acta derm.-"},{"key":"ref_15","first-page":"164","volume":"39","author":"WILLCOX, R.R.","year":"1963","unstructured":"WILLCOX, R. R. (1963). Brit. J. vener. Dis., 39, 164.","journal-title":"Brit. J. vener. Dis"},{"issue":"40","key":"ref_16","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1136\/pgmj.40.Suppl.202","volume":"3","author":"WILLCOX, R.R.","year":"1964","unstructured":"WILLCOX, R. R. (1964). Postgrad. med. J3. Suppl., 40, 202.","journal-title":"Postgrad"},{"key":"ref_17","first-page":"157","volume":"43","author":"WILLCOX, R.R.","year":"1967","unstructured":"WILLCOX, R. R. (1967). Brit. J7. vener. Dis., 43, 157.","journal-title":"Brit. J7. vener. Dis"},{"key":"ref_18","first-page":"101","article-title":"In 'Current Problems in Dermatology' vol 2, 'Antibiotic Treatment of Venereal Diseases'","author":"WILLCOX, R.R.","year":"1968","unstructured":"WILLCOX, R. R. (1968) In 'Current Problems in Dermatology' vol 2, 'Antibiotic Treatment of Venereal Diseases', ed. A. Luger, p. 101. Karger, Basel."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"103","DOI":"10.2340\/0001555549103105","volume":"49","author":"WILLCOX, R.R.","year":"1969","unstructured":"WILLCOX, R. R. (1969). Acta derm.-venereol. (Stockh.), 49, 103.","journal-title":"Acta derm.-venereol. (Stockh.)"},{"key":"ref_20","article-title":"Report of Second VD Seminar Western Pacific Region","author":"WHO","year":"1969","unstructured":"WHO (1969). Report of Second VD Seminar Western Pacific Region, Manila."},{"key":"ref_21","unstructured":"Chez les malades traites par 2,4 mega-unites de penicilline-procaine en une injection, le taux des &checs fut ramene a 5,8 pour cent, et il en fut de meme (6,6 pour cent) si 1g. de probenecide etait donne par voie buccale en meme temps qu'une injection de 1,2 mega-unites de penicilline-procame.","article-title":"Chez les malades traites par 2,4 mega-unites de penicilline-procaine en une injection, le taux des &checs fut ramene a 5,8 pour cent, et il en fut de meme (6,6 pour cent) si 1g. de probenecide etait donne par voie buccale en meme temps qu'une injection de 1,2 mega-unites de penicilline-procame"},{"key":"ref_22","article-title":"la streptomycine n'est plus assez active dans le traitement de la gonococcie; avec Ig., le taux d'echec a ete de 31,7 pour cent a Londres chez les hommes. Si l'accroissement de la resistance continue au meme rythme, on peut penser que la streptomycine echouera dans 85,8 pour cent des cas vers","author":"Actuellement","year":"1971","unstructured":"Actuellement, la streptomycine n'est plus assez active dans le traitement de la gonococcie; avec Ig., le taux d'echec a ete de 31,7 pour cent a Londres chez les hommes. Si l'accroissement de la resistance continue au meme rythme, on peut penser que la streptomycine echouera dans 85,8 pour cent des cas vers 1971."},{"key":"ref_23","unstructured":"On enumere les nombreux autres antibiotiques actifs contre le gonocoque, mais il faut etre attentif au fait que les souches de gonocoques moins sensibles a la penicilline peuvent devenir egalement insensibles aux autres antibiotiques. On rapporte quelques experiences recentes avec la demethylchlortetracycline donnee per os en deux fois, avec la rifampicine donnee en une seule dose buccale, et avec la rolitetracycline administree par injection en association avec le phosphate de tetracycline donne par la bouche au cours de le meme seance. Des doses uniques de rifampicine ont donne des resultats comparables a ceux qui avaient ete obtenus avec des injesctions uniques de 1,2 mega-unites de penicillineprocaine, mais des resultats superieurs (95,7 pour cent de succes) ont 6t6 obtenus avec deux doses de demethylchlortetracycline donnees par voie buccale.","article-title":"On enumere les nombreux autres antibiotiques actifs contre le gonocoque, mais il faut etre attentif au fait que les souches de gonocoques moins sensibles a la penicilline peuvent devenir egalement insensibles aux autres antibiotiques. On rapporte quelques experiences recentes avec la demethylchlortetracycline donnee per os en deux fois, avec la rifampicine donnee en une seule dose buccale, et avec la rolitetracycline administree par injection en association avec le phosphate de tetracycline donne par la bouche au cours de le meme seance. Des doses uniques de rifampicine ont donne des resultats comparables a ceux qui avaient ete obtenus avec des injesctions uniques de 1,2 mega-unites de penicillineprocaine, mais des resultats superieurs (95,7 pour cent de succes) ont 6t6 obtenus avec deux doses de demethylchlortetracycline donnees par voie buccale"}],"container-title":["Sexually Transmitted Infections"],"original-title":[],"language":"en","deposited":{"date-parts":[[2025,2,2]],"date-time":"2025-02-02T18:27:12Z","timestamp":1738520832000},"score":1,"resource":{"primary":{"URL":"https:\/\/sti.bmj.com\/lookup\/doi\/10.1136\/sti.46.2.141"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1970,4,1]]},"references-count":23,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1970,4,1]]}},"URL":"https:\/\/doi.org\/10.1136\/sti.46.2.141","relation":{},"ISSN":["1368-4973"],"issn-type":[{"type":"print","value":"1368-4973"}],"subject":[],"published":{"date-parts":[[1970,4,1]]}}}