{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,22]],"date-time":"2026-03-22T09:06:11Z","timestamp":1774170371755,"version":"3.50.1"},"reference-count":22,"publisher":"BMJ","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sexually Transmitted Infections"],"published-print":{"date-parts":[[1989,1,1]]},"DOI":"10.1136\/sti.65.1.1","type":"journal-article","created":{"date-parts":[[2008,11,12]],"date-time":"2008-11-12T21:44:35Z","timestamp":1226526275000},"page":"1-3","source":"Crossref","is-referenced-by-count":16,"title":["Primary and secondary syphilis, 20 years' experience. 2. Clinical features."],"prefix":"10.1136","volume":"65","author":[{"given":"A","family":"Mindel","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S J","family":"Tovey","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D J","family":"Timmins","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P","family":"Williams","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","reference":[{"key":"ref_1","first-page":"361","article-title":"Primary and secondary syphilis, 20 years' experience. 1","volume":"63","author":"Mindel, A.; Tovey, S.J.; Williams, P.","year":"1987","unstructured":"Mindel A, Tovey SJ, Williams P. Primary and secondary syphilis, 20 years' experience. 1. Epidemiology. Genitourin Med 1987;63:361-4.","journal-title":"Epidemiology. Genitourin Med"},{"key":"ref_2","article-title":"Treatise on the venereal disease","author":"Hunter, J.","unstructured":"Hunter J. Treatise on the venereal disease. 2nd ed. London: G Nicoll, 1788.","edition":"2nd ed"},{"key":"ref_3","article-title":"Modern clinical syphilology","author":"Stokes, J.H.; Beerman, H.; Ingraham, N.R.","year":"1944","unstructured":"Stokes JH, Beerman H, Ingraham NR. Modern clinical syphilology. 3rd ed. Philadelphia: Saunders, 1944.","edition":"3rd ed"},{"key":"ref_4","article-title":"Essentials of syphilology","author":"Kampmeier, R.H.","year":"1944","unstructured":"Kampmeier RH. Essentials of syphilology. Oxford: Blackwell Scientific, 1944."},{"key":"ref_5","first-page":"207","article-title":"Syphilis the change in clinical manifestations","volume-title":"transmitted diseases","author":"Knox, J.M.","year":"1976","unstructured":"Knox JM. Syphilis the change in clinical manifestations. In: Catterall RD, Nicol CS, eds. Sexually transmitted diseases. London: Academic Press, 1976:207-9."},{"key":"ref_6","article-title":"Treponemal infections. WHO Tech Rep Ser 1982: No 674","author":"World Health Organisation","unstructured":"World Health Organisation. Treponemal infections. WHO Tech Rep Ser 1982: No 674."},{"key":"ref_7","first-page":"329","article-title":"British Co-Operative Clinical Group. Homosexuality and venereal diseases in the United Kingdom","volume":"49","year":"1973","unstructured":"British Co-Operative Clinical Group. Homosexuality and venereal diseases in the United Kingdom. British Journal of Venereal Diseases 1973;49:329-34.","journal-title":"British Journal of Venereal Diseases"},{"key":"ref_8","first-page":"6","article-title":"British Co-Operative Clinical Group. Homosexuality and venereal disease in the United Kingdom","volume":"56","year":"1980","unstructured":"British Co-Operative Clinical Group. Homosexuality and venereal disease in the United Kingdom. British Journal of Venereal Diseases 1980;56:6-11.","journal-title":"British Journal of Venereal Diseases"},{"issue":"534 40","key":"ref_9","article-title":"Studies on the recent epidemiology ofearly syphilis in West London","volume":"48","author":"Waugh, M.A.","year":"1972","unstructured":"Waugh MA. Studies on the recent epidemiology ofearly syphilis in West London. British Journal of Venereal Diseases 1972;48: 534 40.","journal-title":"British Journal of Venereal Diseases"},{"key":"ref_10","first-page":"169","article-title":"Changing patterns of treponemal disease","volume":"50","author":"Willcox, R.R.","year":"1974","unstructured":"Willcox RR. Changing patterns of treponemal disease. British Journal of Venereal Diseases 1974;50:169-78.","journal-title":"British Journal of Venereal Diseases"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1097\/00000658-197607000-00011","article-title":"The role ofsurgery in primary syphilis of the anus","volume":"184","author":"Drusin, L.M.; Homan, W.P.; Dineen, P.","year":"1976","unstructured":"1 Drusin LM, Homan WP, Dineen P. The role ofsurgery in primary syphilis of the anus. Ann Surg 1976;184:65-7.","journal-title":"Ann Surg"},{"key":"ref_12","first-page":"345","article-title":"Extragenital chancres: a survey of 219 cases","volume":"32","author":"Tucker, H.A.; Mulherin, J.L.","year":"1948","unstructured":"Tucker HA, Mulherin JL. Extragenital chancres: a survey of 219 cases. American Journal of Syphilis, Gonorrhea and Venereal Diseases 1948;32:345-64.","journal-title":"American Journal of Syphilis, Gonorrhea and Venereal Diseases"},{"key":"ref_13","first-page":"173","article-title":"The primary lesions and early secondary symptoms of syphilis as seen in the male","volume-title":"A system of syphilis. Vol 1","author":"Lambkin, F.J.","unstructured":"Lambkin FJ. The primary lesions and early secondary symptoms of syphilis as seen in the male. In: Power D, Murphy JK, eds. A system of syphilis. Vol 1. Oxford: Oxford University Press, 1914:173-221."},{"key":"ref_14","first-page":"225","article-title":"The primary lesions and early secondary symptoms as seen in the female","volume-title":"A system of syphilis. Vol 1","author":"Shillitoe, A.","unstructured":"Shillitoe A. The primary lesions and early secondary symptoms as seen in the female. In: Power D, Murphy JK, eds. A system of syphilis. Vol 1. Oxford: Oxford Medical Publications, 1914: 225-80."},{"key":"ref_15","first-page":"529","article-title":"Syphilis of the liver","volume":"27","author":"Hahn, R.D.","year":"1943","unstructured":"Hahn RD. Syphilis of the liver. American Journal of Syphilis, Gonorrhoea and Venereal Diseases 1943;27:529-62.","journal-title":"American Journal of Syphilis, Gonorrhoea and Venereal Diseases"},{"issue":"12","key":"ref_16","article-title":"Secondary syphilis and hepatitis","volume":"1","author":"Anonymous","year":"1975","unstructured":"Anonymous. Secondary syphilis and hepatitis. Br Med J 1975;i:1 12.","journal-title":"Br Med J"},{"key":"ref_17","first-page":"896","article-title":"Early syphilitic hepatitis","volume":"ii:","author":"FeherJ, Somogyi T.; M, Timmer; L, Jozsa","year":"1975","unstructured":"FeherJ, Somogyi T, Timmer M, Jozsa L. Early syphilitic hepatitis. Lancet 1975;ii:896-9.","journal-title":"Lancet"},{"key":"ref_18","first-page":"32","article-title":"Uncommon complications ofearly syphilis, hepatitis, periostitis, iritis with papillitis, and meningitis","volume":"48","author":"Parker, J.D.J.","year":"1972","unstructured":"Parker JDJ. Uncommon complications ofearly syphilis, hepatitis, periostitis, iritis with papillitis, and meningitis. British Journal of Venereal Diseases 1972;48:32-6.","journal-title":"British Journal of Venereal Diseases"},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"1423","DOI":"10.1056\/NEJM197106242842508","article-title":"Liver disease associated with secondary syphilis","volume":"284","author":"Lee, R.V.; Thornton, G.F.; Corn, H.O.","year":"1971","unstructured":"Lee RV, Thornton GF, Corn HO. Liver disease associated with secondary syphilis. N Engl J Med 1971;284:1423-5.","journal-title":"N Engl J Med"},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"1569","DOI":"10.1056\/NEJM198706183162503","article-title":"Alteration in the natural history of neurosyphilis by concurrent infection with the human immunodeficiency virus","volume":"316","author":"Johns, D.R.; Tierney, M.; Felsenstein, D.","year":"1987","unstructured":"Johns DR, Tierney M, Felsenstein D. Alteration in the natural history of neurosyphilis by concurrent infection with the human immunodeficiency virus. N Engl J Med 1987;316: 1569-72.","journal-title":"N Engl J Med"},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"1587","DOI":"10.1056\/NEJM198706183162507","article-title":"Neurologic relapse after benzathine penicillin therapy for secondary syphilis in a patient with HIV infection","volume":"316","author":"Berry, C.D.; Houton, T.M.; Collier, A.C.; Lukehart, S.A.","year":"1987","unstructured":"Berry CD, Houton TM, Collier AC, Lukehart SA. Neurologic relapse after benzathine penicillin therapy for secondary syphilis in a patient with HIV infection. N Engl J Med 1987;316:1587-9.","journal-title":"N Engl J Med"},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"1600","DOI":"10.1056\/NEJM198706183162510","article-title":"Syphilis in the AIDS era","volume":"316","author":"Tramont, E.C.","year":"1987","unstructured":"Tramont EC. Syphilis in the AIDS era. N Engl J Med 1987;316:1600-1.","journal-title":"N Engl J Med"}],"container-title":["Sexually Transmitted Infections"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/sti.65.1.1","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,9,25]],"date-time":"2020-09-25T23:49:08Z","timestamp":1601077748000},"score":1,"resource":{"primary":{"URL":"https:\/\/sti.bmj.com\/lookup\/doi\/10.1136\/sti.65.1.1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1989,1,1]]},"references-count":22,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1989,1,1]]}},"URL":"https:\/\/doi.org\/10.1136\/sti.65.1.1","relation":{},"ISSN":["1368-4973"],"issn-type":[{"value":"1368-4973","type":"print"}],"subject":[],"published":{"date-parts":[[1989,1,1]]}}}