{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,4,6]],"date-time":"2022-04-06T02:35:38Z","timestamp":1649212538407},"reference-count":13,"publisher":"BMJ","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sexually Transmitted Infections"],"published-print":{"date-parts":[[1989,6,1]]},"DOI":"10.1136\/sti.65.3.200-a","type":"journal-article","created":{"date-parts":[[2008,11,12]],"date-time":"2008-11-12T21:44:35Z","timestamp":1226526275000},"page":"200-201","source":"Crossref","is-referenced-by-count":0,"title":["Trichomonal vaginitis refractory to conventional treatment."],"prefix":"10.1136","volume":"65","author":[{"given":"S A","family":"Seligman","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","reference":[{"key":"ref_1","first-page":"25","article-title":"Managing trichomonal vaginitis refractory to conventional treatment with metronidazole","volume":"64","author":"Ahmed-Jushuf, I.H.; Murray, A.E.; McKeown, J.","year":"1988","unstructured":"Ahmed-Jushuf IH, Murray AE, McKeown J. Managing trichomonal vaginitis refractory to conventional treatment with metronidazole. Genitourin Med 1988;64:25-9.","journal-title":"Genitourin Med"},{"key":"ref_2","first-page":"217","article-title":"Treatment failure in Trichomonas vaginalis vaginitis","volume":"64","author":"Lumsden, W.H.R.; Robertson, D.H.H.; Heyworth, R.; Harrison, C.","year":"1988","unstructured":"Lumsden WHR, Robertson DHH, Heyworth R, Harrison C. Treatment failure in Trichomonas vaginalis vaginitis. Genitourin Med 1988;64:217-8.","journal-title":"Genitourin Med"},{"key":"ref_3","first-page":"369","article-title":"Trichomonal vaginitis refractory to treatment: case report","volume":"64","author":"Sprott, M.S.; Kearns, A.M.; Pattman, R.S.","year":"1988","unstructured":"Sprott MS, Kearns AM, Pattman RS. Trichomonal vaginitis refractory to treatment: case report. Genitourin Med 1988;64:369-72.","journal-title":"Genitourin Med"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"948","DOI":"10.1093\/infdis\/153.5.948","article-title":"In vitro drug susceptibility and doses of metronidazole required for cure in cases of refractory vaginal trichomoniasis","volume":"153","author":"Lossick, J.G.; Muiller, M.; Gorrell, T.E.","year":"1986","unstructured":"Lossick JG, Muiller M, Gorrell TE. In vitro drug susceptibility and doses of metronidazole required for cure in cases of refractory vaginal trichomoniasis. J Infect Dis 1986; 153:948-55.","journal-title":"J Infect Dis"},{"issue":"555-64","key":"ref_5","first-page":"2","article-title":"In vitro estimation of the sensitivity of the organism to metronidazole","volume":"21","author":"Milovanovic, R.; Grcic, R.; Stojkovic, L.","year":"1988","unstructured":"In vitro estimation of the sensitivity of the organism to metronidazole. J Antimicrob Chemother 1988;21: 555-64. 6 Milovanovic R, Grcic R, Stojkovic L. Serological study with SolcoTrichovac, a vaccine against Trichomonas vaginalis in women. Gyndkol Rundsch 1982;22suppl 2: 39-45.","journal-title":"J Antimicrob Chemother; Serological study with SolcoTrichovac, a vaccine against Trichomonas vaginalis in women"},{"key":"ref_6","first-page":"1","article-title":"Vaginal lactobacilli","volume":"6","author":"Seligman, S.A.; Stannard, A.J.; Willis, A.T.","year":"1986","unstructured":"Seligman SA, Stannard AJ, Willis AT. Vaginal lactobacilli. J Obstet Gynaecol 1986;6suppl 1:47-9.","journal-title":"J Obstet Gynaecol"},{"key":"ref_7","article-title":"A West Indian man aged 24 attended the genitourinary medicine clinic at the Manchester Royal Infirmary in July 1988 with a recurrence of penile warts. He had been treated at the clinic once before, from December 1985 to August 1986, for genital warts and non-gonococcal urethritis. In 1986, while being treated for warts with 25% podophyllin in glycerol, he had developed a local reaction to podophyllin which had resulted in skin erosions on the foreskin. Podophyllin treatment had been discontinued immediately, and the skin erosions had been treated by using saline baths and giving co-trimoxazole tablets for five days. The skin had healed satisfactorily and the warts had disappeared before he was discharged in","author":"Sir","year":"1986","unstructured":"Sir, A West Indian man aged 24 attended the genitourinary medicine clinic at the Manchester Royal Infirmary in July 1988 with a recurrence of penile warts. He had been treated at the clinic once before, from December 1985 to August 1986, for genital warts and non-gonococcal urethritis. In 1986, while being treated for warts with 25% podophyllin in glycerol, he had developed a local reaction to podophyllin which had resulted in skin erosions on the foreskin. Podophyllin treatment had been discontinued immediately, and the skin erosions had been treated by using saline baths and giving co-trimoxazole tablets for five days. The skin had healed satisfactorily and the warts had disappeared before he was discharged in August 1986."},{"key":"ref_8","article-title":"When he attended again in July 1988, he was found to have a large hyperkeratotic wart on the foreskin and a large (18 mm in diameter) well healed circular hole on the Figure Circular hole (18 mm in diameter) in dorsal aspect offoreskin","unstructured":"When he attended again in July 1988, he was found to have a large hyperkeratotic wart on the foreskin and a large (18 mm in diameter) well healed circular hole on the Figure Circular hole (18 mm in diameter) in dorsal aspect offoreskin."},{"key":"ref_9","article-title":"dorsal aspect of the foreskin-like a round window (fig). No evidence of any other sexually transmitted disease was found. When questioned about the hole in the foreskin, he replied that it had developed seven to eight months after the podophyllin reaction that he had experienced in August 1986. He said that he had not treated himself in any way or received treatment elsewhere during the intervening two years. He had abstained from sexual intercourse for the previous 12 months. His wart was removed with cryotherapy, and he was referred to a surgeon for circumcision for cosmetic reasons","unstructured":"dorsal aspect of the foreskin-like a round window (fig). No evidence of any other sexually transmitted disease was found. When questioned about the hole in the foreskin, he replied that it had developed seven to eight months after the podophyllin reaction that he had experienced in August 1986. He said that he had not treated himself in any way or received treatment elsewhere during the intervening two years. He had abstained from sexual intercourse for the previous 12 months. His wart was removed with cryotherapy, and he was referred to a surgeon for circumcision for cosmetic reasons."},{"key":"ref_10","article-title":"The interesting features that attracted our attention to this case were, firstly, the patient's lack of concern about the obvious foreskin deformity, and, secondly, the long interval (seven to eight months) between the recorded podophyllin reaction in August 1986 and the appearance of the hole in the foreskin, especially as he had had no ulceration and the skin had healed satisfactorily when he had been discharged from the clinic in 1986. His lack of concern about the obvious deformity of the foreskin made us think that this possibly could have been the result of either self treatment or treatment he had received elsewhere, which is of course difficult to prove","unstructured":"The interesting features that attracted our attention to this case were, firstly, the patient's lack of concern about the obvious foreskin deformity, and, secondly, the long interval (seven to eight months) between the recorded podophyllin reaction in August 1986 and the appearance of the hole in the foreskin, especially as he had had no ulceration and the skin had healed satisfactorily when he had been discharged from the clinic in 1986. His lack of concern about the obvious deformity of the foreskin made us think that this possibly could have been the result of either self treatment or treatment he had received elsewhere, which is of course difficult to prove."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1001\/archderm.1947.01520070033004","article-title":"Effects of resin of podophyllin on normal skin, condylomata acuminata and verrucae vulgaris","volume":"56","author":"Sullivan, M.; King, L.","year":"1947","unstructured":"Sullivan M, King L. Effects of resin of podophyllin on normal skin, condylomata acuminata and verrucae vulgaris. Archives of Dermatology and Syphilology 1947;56:30-47.","journal-title":"Archives of Dermatology and Syphilology"},{"key":"ref_12","article-title":"ABC of sexually transmitted diseases","author":"Adler, M.W.","unstructured":"Adler MW. ABC of sexually transmitted diseases. 2nd ed. London: BMJ, 1985:30.","edition":"2nd ed"},{"key":"ref_13","first-page":"37","article-title":"Self-treatment of condylomata acuminata with podophyllin resin","volume":"229","author":"Maiti, H.; Haye, K.R.","year":"1985","unstructured":"Maiti H, Haye KR. Self-treatment of condylomata acuminata with podophyllin resin. Practitioner 1985;229:37-9.","journal-title":"Practitioner"}],"container-title":["Sexually Transmitted Infections"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/sti.65.3.200-a","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,9,25]],"date-time":"2020-09-25T23:49:28Z","timestamp":1601077768000},"score":1,"resource":{"primary":{"URL":"https:\/\/sti.bmj.com\/lookup\/doi\/10.1136\/sti.65.3.200-a"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1989,6,1]]},"references-count":13,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1989,6,1]]}},"URL":"https:\/\/doi.org\/10.1136\/sti.65.3.200-a","relation":{},"ISSN":["1368-4973"],"issn-type":[{"value":"1368-4973","type":"print"}],"subject":[],"published":{"date-parts":[[1989,6,1]]}}}