{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,4,3]],"date-time":"2022-04-03T20:17:21Z","timestamp":1649017041981},"reference-count":10,"publisher":"BMJ","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sexually Transmitted Infections"],"published-print":{"date-parts":[[1995,6,1]]},"DOI":"10.1136\/sti.71.3.187","type":"journal-article","created":{"date-parts":[[2008,11,12]],"date-time":"2008-11-12T21:44:35Z","timestamp":1226526275000},"page":"187-192","source":"Crossref","is-referenced-by-count":0,"title":["Disseminated cryptococcal infection despite treatment for cryptococcal meningitis."],"prefix":"10.1136","volume":"71","author":[{"given":"R F","family":"Miller","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S B","family":"Lucas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K M","family":"De Cock","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R J","family":"Hay","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","reference":[{"key":"ref_1","article-title":"Subsequently the patient was maintained on oral fluconazole 400 mg daily. This was discontinued in October 1989 because of abnormal liver function tests. The patient rapidly developed headache and was admitted in November of that year. Investigations then showed normal urea and electrolyte levels and liver function tests and negative blood cultures. Blood CRAG was 1 in 5000, CSF CRAG was 1 in 1026. Cultures of CSF were positive for C neoformans. The patient was given a further course of intravenous amphotericin B for four weeks and subsequently a Hickman line was inserted; he then received 0.5 mg\/kg of amphotericin intravenously once weekly, as maintenance therapy and began Fansidar two tablets once weekly for primary prophylaxis against pneumocystis pneumonia","unstructured":"Subsequently the patient was maintained on oral fluconazole 400 mg daily. This was discontinued in October 1989 because of abnormal liver function tests. The patient rapidly developed headache and was admitted in November of that year. Investigations then showed normal urea and electrolyte levels and liver function tests and negative blood cultures. Blood CRAG was 1 in 5000, CSF CRAG was 1 in 1026. Cultures of CSF were positive for C neoformans. The patient was given a further course of intravenous amphotericin B for four weeks and subsequently a Hickman line was inserted; he then received 0.5 mg\/kg of amphotericin intravenously once weekly, as maintenance therapy and began Fansidar two tablets once weekly for primary prophylaxis against pneumocystis pneumonia."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"234","DOI":"10.7326\/0003-4819-104-2-234","article-title":"Cryptococcal disease in patients with the acquired immunodeficiency syndrome: diagnostic features and outcome of treatment","volume":"104","author":"Zuger, A.; Louie, E.; Holzman, R.S.; Simberkoff, M.S.; Rahal, J.J.","year":"1986","unstructured":"Zuger A, Louie E, Holzman RS, Simberkoff MS, Rahal JJ. 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Itraconazole compared with amphotericin B plus flyuytosine in AIDS patients with cryptococcal meningitis. AIDS 1992;6: 185-190.","journal-title":"AIDS"},{"key":"ref_8","first-page":"151","article-title":"Cryptococcal meningoencephalitis in AIDS","author":"Murphy, S.A.; Denning, D.W.","year":"1994","unstructured":"Murphy SA, Denning DW. Cryptococcal meningoencephalitis in AIDS. Hospital Update 1994:151-6.","journal-title":"Hospital Update"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1097\/00002030-199306000-00011","article-title":"Treatment of cryptococcosis with liposomal amphotericin B","volume":"7","author":"Coker, R.J.; Viviani, M.; Gazzard, B.G.","year":"1993","unstructured":"Coker RJ, Viviani M, Gazzard BG, et al. Treatment of cryptococcosis with liposomal amphotericin B. AIDS 1993;7:829-35.","journal-title":"AIDS"},{"key":"ref_10","first-page":"179","article-title":"Capsule synthesis and immunity to Cryptococcus neoformans. In New Strategies in Fungal Disease","author":"Bancroft, G.J.; Rockett, E.R.; Collins, H.L.","year":"1993","unstructured":"Bancroft GJ, Rockett ER, Collins HL. Capsule synthesis and immunity to Cryptococcus neoformans. In New Strategies in Fungal Disease. 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