{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T01:40:33Z","timestamp":1787017233502,"version":"build-2736575974"},"reference-count":23,"publisher":"BMJ","issue":"3","funder":[{"name":"The 12th Five-Year Plan\u2019 of the Ministry of Science and Technology"},{"name":"Beijing High-level Personnel Funds"},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["Stroke Vasc Neurol"],"accepted":{"date-parts":[[2018,3,4]]},"published-print":{"date-parts":[[2018,9]]},"abstract":"<jats:sec>\n                    <jats:title>Background and purpose<\/jats:title>\n                    <jats:p>A multicentre prospective registry study of individually tailored stenting for a patient with symptomatic intracranial atherosclerotic stenosis (ICAS) combined with poor collaterals in China showed that the short-term safety and efficacy of stenting was acceptable. However, it remained uncertain whether the low event rate could be of a long term. We reported the 1-year outcome of this registry study to evaluate the long-term efficacy of individually tailored stenting for patients with severe symptomatic ICAS combined with poor collaterals.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Patients with symptomatic ICAS caused by 70%\u201399%\u2009stenosis located at the intracranial internal carotid, middle cerebral, intracranial vertebral or basilar arteries combined with poor collaterals were enrolled. Balloon-mounted stent or balloon plus self-expanding stent were selected based on the ease of vascular access and lesion morphology determined by the operators. The primary outcome was the rate of 30-day stroke, transient ischaemic attack and death, and 12-month ischaemic stroke within the same vascular territory, haemorrhagic stroke and vascular death after stenting.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>From September 2013 to January 2015, 300 patients (ages 58.3\u00b19.78 years) were recruited. Among them, 159 patients were treated with balloon-mounted stent and 141 with balloon plus self-expanding stent. During the 1-year follow-up, 25 patients had a primary end point event. The probability of primary outcome at 1\u2009year was 8.1% (95% CI 5.3% to 11.7%). In 76 patients with digital subtraction angiography follow-up, 27.6% (21\/76) had re-stenosis \u226550%\u2009and 18.4% (14\/76) had re-stenosis \u226570%. No baseline characteristic was associated with the primary outcome.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The event rate remains low over 1\u2009year of individually tailored stenting for patients with severe symptomatic ICAS combined with poor collaterals. Further randomised trial of comparing individually tailored stenting with best medical therapy is needed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Trial registration number<\/jats:title>\n                    <jats:p>\n                      <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"NCT01968122\" ext-link-type=\"clintrialgov\" specific-use=\"clinicaltrial results\">NCT01968122<\/jats:ext-link>\n                      ; Results.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1136\/svn-2017-000137","type":"journal-article","created":{"date-parts":[[2018,9,24]],"date-time":"2018-09-24T10:24:26Z","timestamp":1537784666000},"page":"176-184","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":68,"title":["Stenting for symptomatic intracranial arterial stenosis in China: 1-year outcome of a multicentre registry study"],"prefix":"10.1136","volume":"3","clinical-trial-number":[{"clinical-trial-number":"nct01968122","registry":"10.18810\/clinical-trials-gov","type":"results"}],"author":[{"given":"Ning","family":"Ma","sequence":"first","affiliation":[{"name":"Department of Interventional Neurology, Beijing Tiantan Hospital, Capital Medical University, China National Clinical Research Center for Neurological Diseases, Center of Stroke, Beijing Institute for Brain Disorders, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yong","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Neurology, The Affiliated Hospital of Qingdao University Medical College, Qingdao, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jie","family":"Shuai","sequence":"additional","affiliation":[{"name":"Department of Neurology, Xin Qiao Hospital, Third Military Medical University, Chongqing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Changchun","family":"Jiang","sequence":"additional","affiliation":[{"name":"Department of Neurology, Baotou Central Hospital, Baotou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiyi","family":"Zhu","sequence":"additional","affiliation":[{"name":"Department of Neurology, Linyi People\u2019s Hospital, Linyi, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kangning","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Neurology, Xi Nan Hospital, Third Military Medical University, Chongqing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Neurology, The Hospital of Chifeng City, Chifeng, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Baomin","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, The PLA General Hospital, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiangqun","family":"Shi","sequence":"additional","affiliation":[{"name":"Department of Neurology, The Lanzhou General Hospital of PLA, Lanzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lianbo","family":"Gao","sequence":"additional","affiliation":[{"name":"Department of Neurology, The Affiliated Fourth Hospital of China Medical University, Shenyang, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yajie","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Neurology, Zhujiang Hospital, Southern Medical University, Guangzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Feng","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Interventional Therapy, The First Affiliated Hospital of Dalian Medical University, Dalian, 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