{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,17]],"date-time":"2026-03-17T06:42:03Z","timestamp":1773729723540,"version":"3.50.1"},"reference-count":20,"publisher":"BMJ","issue":"3","funder":[{"name":"Beijing Municipal Administration of Hospitals\u2019 Mission Plan"},{"name":"Beijing Municipal Committee of Science and Technology"},{"name":"Beijing BaiQianWan Talents Program"},{"DOI":"10.13039\/501100012166","name":"National Key R&D Program of China","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["Stroke Vasc Neurol"],"accepted":{"date-parts":[[2019,4,16]]},"published-print":{"date-parts":[[2019,9]]},"abstract":"<jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>In 2009, China launched ambitious healthcare reform plans to provide affordable and equitable basic healthcare for all patients, including the substantial number of patients who had a stroke. However, little is known about the pattern of evidence-based stroke care and outcomes across hospitals, regions and time during the last decade.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Aims<\/jats:title>\n                  <jats:p>The Patient-centered Retrospective Observation of Guideline-Recommended Execution for Stroke Sufferers in China (China PROGRESS) Study aims to use findings from a representative sample of Chinese hospitals over the last decade to improve future stroke care for patients hospitalised with ischaemic stroke (IS) or transient ischaemic attack (TIA).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Design<\/jats:title>\n                  <jats:p>The China PROGRESS Study will use a two-stage cluster sampling method to identify over 32000 patient records from 208 hospitals across the Eastern, Central and Western geographical regions in China. To assess the temporal trends in patient characteristics, treatment and outcomes, study investigators will select records from 2005, 2010 and 2015. A double data reading\/entry system will be developed to conduct this assessment. A central coordinating centre will monitor case ascertainment, data abstraction and data management. Analyses will examine patient characteristics, testing patterns, in-hospital treatment and outcomes, and variations across regions and across time.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>The China PROGRESS Study is the first nationally representative study that aims to better understand care quality and outcomes for patients with IS or TIA before and after the national healthcare reform in China. This initiative will translate findings into clinical practices that improve care quality for patients who had a stroke and policy recommendations that allow these changes to be implemented widely.<\/jats:p>\n                  <jats:p>\n                     <jats:bold>Ethics approval<\/jats:bold>\n                  <\/jats:p>\n                  <jats:p>This study has also been approved by the central institutional review board (IRB) at Beijing Tiantan Hospital.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1136\/svn-2019-000233","type":"journal-article","created":{"date-parts":[[2019,5,13]],"date-time":"2019-05-13T05:10:49Z","timestamp":1557724249000},"page":"165-170","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":6,"title":["Rationale and design of Patient-centered Retrospective Observation of Guideline-Recommended Execution for Stroke Sufferers in China: China PROGRESS"],"prefix":"10.1136","volume":"4","author":[{"given":"Zixiao","family":"Li","sequence":"first","affiliation":[{"name":"Vascular Neurology, Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China"},{"name":"China National Clinical Research Center for Neurological Diseases, Beijing, China"},{"name":"Center of Stroke, Beijing Institute for BrainDisorders, Beijing, China"},{"name":"Beijing Key Laboratory of Translational Medicine forCerebrovascular Disease, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chunjuan","family":"Wang","sequence":"additional","affiliation":[{"name":"China National Clinical Research Center for Neurological Diseases, Beijing, China"},{"name":"Center of Stroke, Beijing Institute for BrainDisorders, Beijing, China"},{"name":"Beijing Key Laboratory of Translational Medicine forCerebrovascular Disease, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yong","family":"Jiang","sequence":"additional","affiliation":[{"name":"China National Clinical Research Center for Neurological Diseases, Beijing, China"},{"name":"Center of Stroke, Beijing Institute for BrainDisorders, Beijing, China"},{"name":"Beijing Key Laboratory of Translational Medicine forCerebrovascular Disease, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xinmiao","family":"Zhang","sequence":"additional","affiliation":[{"name":"Vascular Neurology, Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China"},{"name":"Center of Stroke, Beijing Institute for BrainDisorders, Beijing, China"},{"name":"Beijing Key Laboratory of Translational Medicine forCerebrovascular Disease, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ying","family":"Xian","sequence":"additional","affiliation":[{"name":"Duke Clinical Research Institute, North Carolina, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liping","family":"Liu","sequence":"additional","affiliation":[{"name":"China National Clinical Research Center for Neurological Diseases, Beijing, China"},{"name":"Center of Stroke, Beijing Institute for BrainDisorders, Beijing, China"},{"name":"Beijing Key Laboratory of Translational Medicine forCerebrovascular Disease, Beijing, China"},{"name":"Neuro-intensive Care Unit, Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xingquan","family":"Zhao","sequence":"additional","affiliation":[{"name":"Vascular Neurology, Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China"},{"name":"China National Clinical Research Center for Neurological Diseases, Beijing, China"},{"name":"Center of Stroke, Beijing Institute for BrainDisorders, Beijing, 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