{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T19:59:31Z","timestamp":1782935971496,"version":"3.54.5"},"reference-count":41,"publisher":"BMJ","issue":"1","license":[{"start":{"date-parts":[[2023,11,8]],"date-time":"2023-11-08T00:00:00Z","timestamp":1699401600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000308","name":"British Council","doi-asserted-by":"publisher","award":["527635178"],"award-info":[{"award-number":["527635178"]}],"id":[{"id":"10.13039\/501100000308","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000308","name":"British Council","doi-asserted-by":"publisher","award":["SECTEI\/203\/2019"],"award-info":[{"award-number":["SECTEI\/203\/2019"]}],"id":[{"id":"10.13039\/501100000308","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["Thorax"],"accepted":{"date-parts":[[2023,9,22]]},"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Previous studies found exposure to air pollution leads to exacerbations of asthma in paediatric and adult patients and increases asthma-related emergency hospital admissions (AREHA).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>AREHAs and levels of air pollutants (PM<jats:sub>10<\/jats:sub>, PM<jats:sub>2.5<\/jats:sub>and NO<jats:sub>2<\/jats:sub>) were obtained from Mexico City for the period 2017\u20132019. A time-series approach was used to explore the relationship between air pollutants and AREHA. Relative risks of AREHA were estimated using a negative binomial regression in young children (less than 5 years) and adults (greater than 18 years).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There was a positive association between AREHA and PM<jats:sub>10<\/jats:sub>, PM<jats:sub>2.5<\/jats:sub>and NO<jats:sub>2<\/jats:sub>in adults, which remained after mutual adjustment for these pollutants. The relative risk (RR) of admission in adults increased by 3% (95% CI 1% to 4%) for a 10 \u00b5g\/m<jats:sup>3<\/jats:sup>increase in PM<jats:sub>10<\/jats:sub>, 1% (0.03% to 3%) for a 5 \u00b5g\/m<jats:sup>3<\/jats:sup>increase in PM<jats:sub>2.5<\/jats:sub>and by 1% (0.06% to 2%) for a 5 \u00b5g\/m<jats:sup>3<\/jats:sup>increase in NO<jats:sub>2<\/jats:sub>. In contrast, in young children, AREHAs were negatively associated with PM<jats:sub>10<\/jats:sub>after adjustment for NO<jats:sub>2<\/jats:sub>(RR 0.97 (0.95 to 0.99) for a 10 \u00b5g\/m<jats:sup>3<\/jats:sup>and with NO<jats:sub>2<\/jats:sub>after adjustment for PM<jats:sub>10<\/jats:sub>and PM<jats:sub>2.5<\/jats:sub>(RR 0.98 (0.96 to 0.99) and 0.97 (0.96 to 0.99), respectively, for a 5 \u00b5g\/m<jats:sup>3<\/jats:sup>increase in NO<jats:sub>2<\/jats:sub>). AREHAs in children were not associated with PM<jats:sub>2.5<\/jats:sub>after adjustment for NO<jats:sub>2<\/jats:sub>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Ambient air pollution, within the previous week, was associated with emergency hospital admissions for asthma to public hospitals in adults in Mexico City. The relationship in children was less consistent. Further work is needed to explore why differences between adults and children exist to inform appropriate interventions to benefit public health.<\/jats:p><\/jats:sec>","DOI":"10.1136\/thorax-2022-219262","type":"journal-article","created":{"date-parts":[[2023,11,8]],"date-time":"2023-11-08T18:21:19Z","timestamp":1699467679000},"page":"43-49","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":9,"title":["Relationship between air quality and asthma-related emergency hospital admissions in Mexico City 2017\u20132019"],"prefix":"10.1136","volume":"79","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6442-4150","authenticated-orcid":false,"given":"Louise","family":"Hayes","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan Manuel","family":"Mejia-Arangure","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adam","family":"Errington","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lindsay","family":"Bramwell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elizabeth","family":"Vega","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan Carlos","family":"Nunez-Enriquez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anil","family":"Namdeo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jane","family":"Entwistle","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yosune","family":"Miquelajauregui","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M\u00f3nica","family":"Jaimes-Palomera","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nancy","family":"Torres","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R Alberto","family":"Rasc\u00f3n-Pacheco","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David A","family":"Duarte-Rodr\u00edguez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard","family":"McNally","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2023,11,8]]},"reference":[{"key":"2024051320322422000_79.1.43.1","unstructured":"World Health Organisation . Effects of Air Pollution on Children\u2019s Health and Development: A Review of the Evidence. Bonn Office: European Centre for Environment Health, 2005."},{"key":"2024051320322422000_79.1.43.2","first-page":"40","article-title":"Management of acute asthma exacerbations","volume":"84","author":"Pollart","year":"2011","journal-title":"Am Fam Physician"},{"key":"2024051320322422000_79.1.43.3","doi-asserted-by":"crossref","DOI":"10.3389\/fped.2018.00186","article-title":"The burden of pediatric asthma","volume":"6","author":"Ferrante","year":"2018","journal-title":"Front Pediatr"},{"key":"2024051320322422000_79.1.43.4","doi-asserted-by":"crossref","first-page":"432","DOI":"10.1016\/j.jped.2019.02.006","article-title":"Asthma mortality in children and adolescents of Brazil over a 20-year period","volume":"96","author":"Pitchon","year":"2020","journal-title":"Jornal de Pediatria"},{"key":"2024051320322422000_79.1.43.5","doi-asserted-by":"publisher","DOI":"10.1097\/MCP.0b013e32834db288"},{"key":"2024051320322422000_79.1.43.6","doi-asserted-by":"publisher","DOI":"10.1136\/jech.2009.083576"},{"key":"2024051320322422000_79.1.43.7","doi-asserted-by":"publisher","DOI":"10.1007\/s11356-015-5321-x"},{"key":"2024051320322422000_79.1.43.8","unstructured":"European Environment Agency . Outdoor air quality in urban areas. 2019. Available: https:\/\/www.eea.europa.eu\/airs\/2018\/environment-and-health\/outdoor-air-quality-urban-areas [Accessed 26 Jan 2022]."},{"key":"2024051320322422000_79.1.43.9","doi-asserted-by":"publisher","DOI":"10.1007\/s11869-011-0144-5"},{"key":"2024051320322422000_79.1.43.10","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.00083614"},{"key":"2024051320322422000_79.1.43.11","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/j.envres.2012.05.001","article-title":"Motor vehicle air pollution and asthma in children: a meta-analysis","volume":"117","author":"Gasana","year":"2012","journal-title":"Environ Res"},{"key":"2024051320322422000_79.1.43.12","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0174050","article-title":"Effect of outdoor air pollution on asthma exacerbations in children and adults: systematic review and multilevel meta-analysis","volume":"12","author":"Orellano","year":"2017","journal-title":"PLoS ONE"},{"key":"2024051320322422000_79.1.43.13","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0042232","article-title":"The association between cold spells and pediatric outpatient visits for asthma in Shanghai, China","volume":"7","author":"Guo","year":"2012","journal-title":"PLoS ONE"},{"key":"2024051320322422000_79.1.43.14","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0102475","article-title":"Effects of meteorological factors on daily hospital admissions for asthma in adults: a time-series analysis","volume":"9","author":"Zhang","year":"2014","journal-title":"PLoS ONE"},{"key":"2024051320322422000_79.1.43.15","doi-asserted-by":"publisher","DOI":"10.1136\/thoraxjnl-2015-208054"},{"key":"2024051320322422000_79.1.43.16","doi-asserted-by":"crossref","first-page":"372","DOI":"10.3390\/atmos12030372","article-title":"Development of a health-based index to identify the association between air pollution and health effects in Mexico city","volume":"12","author":"Cromar","year":"2021","journal-title":"Atmosphere"},{"key":"2024051320322422000_79.1.43.17","unstructured":"Rama. 2022. 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Methodology to Assess Air Pollution Impact on Human Health Using the Generalized Linear Model with Poisson Regression, Air Pollution\u2014Monitoring, Modelling and Health. InTech: Croatia, 2012: 281\u2013304."},{"key":"2024051320322422000_79.1.43.23","unstructured":"Statacorp . Stata statistical software. 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