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Death was the only outcome considered of critical importance. Perceptions of clinical outcomes varied between patients and caregivers. Integrating patients\u2019 perception in the elaboration of clinical trials is essential.<\/jats:p>","DOI":"10.1136\/thorax-2022-219490","type":"journal-article","created":{"date-parts":[[2023,5,4]],"date-time":"2023-05-04T17:21:47Z","timestamp":1683220907000},"page":"721-725","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":8,"title":["Patients\u2019 perceptions on clinical trials outcomes in pulmonary arterial hypertension therapy"],"prefix":"10.1136","volume":"78","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6874-7109","authenticated-orcid":false,"given":"Vicky","family":"Mai","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Camille","family":"Gosselin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u00c9lodie","family":"Tremblay","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabrielle","family":"Rompr\u00e9","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annie Christine","family":"Lajoie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jason","family":"Weatherald","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Christophe","family":"Lega","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S\u00e9bastien","family":"Bonnet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7535-9972","authenticated-orcid":false,"given":"Steeve","family":"Provencher","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2023,5,4]]},"reference":[{"key":"2024051320353077000_78.7.721.1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.12-3023"},{"key":"2024051320353077000_78.7.721.2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2017.12.010"},{"key":"2024051320353077000_78.7.721.3","doi-asserted-by":"crossref","DOI":"10.1183\/13993003.01919-2018","article-title":"The importance of patient perspectives in pulmonary hypertension","volume":"53","author":"McGoon","year":"2019","journal-title":"Eur Respir J"},{"key":"2024051320353077000_78.7.721.4","doi-asserted-by":"publisher","DOI":"10.1183\/09059180.00005713"},{"key":"2024051320353077000_78.7.721.5","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1161\/CIRCULATIONAHA.121.058635","article-title":"Assessment of clinical worsening end points as a surrogate for mortality in pulmonary arterial hypertension: a systematic review and meta-analysis of randomized controlled trials","volume":"146","author":"Tremblay","year":"2022","journal-title":"Circulation"},{"key":"2024051320353077000_78.7.721.6","doi-asserted-by":"publisher","DOI":"10.1002\/sim.5403"},{"key":"2024051320353077000_78.7.721.7","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2009.04.007"},{"key":"2024051320353077000_78.7.721.8","doi-asserted-by":"publisher","DOI":"10.1378\/chest.13-2634"},{"key":"2024051320353077000_78.7.721.9","doi-asserted-by":"publisher","DOI":"10.1023\/A:1016647407161"},{"key":"2024051320353077000_78.7.721.10","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1995.03520250075037"}],"container-title":["Thorax"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/thorax-2022-219490","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,14]],"date-time":"2024-05-14T03:51:07Z","timestamp":1715658667000},"score":1,"resource":{"primary":{"URL":"https:\/\/thorax.bmj.com\/lookup\/doi\/10.1136\/thorax-2022-219490"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,5,4]]},"references-count":10,"journal-issue":{"issue":"7","published-online":{"date-parts":[[2023,6,15]]},"published-print":{"date-parts":[[2023,7]]}},"alternative-id":["10.1136\/thorax-2022-219490"],"URL":"https:\/\/doi.org\/10.1136\/thorax-2022-219490","relation":{},"ISSN":["0040-6376","1468-3296"],"issn-type":[{"value":"0040-6376","type":"print"},{"value":"1468-3296","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,5,4]]}}}