{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,30]],"date-time":"2026-05-30T00:18:15Z","timestamp":1780100295452,"version":"3.54.0"},"reference-count":13,"publisher":"BMJ","issue":"11","funder":[{"name":"NIH NIGMS","award":["T32GM112596"],"award-info":[{"award-number":["T32GM112596"]}]},{"name":"NIH NHLBI","award":["K23HL153759"],"award-info":[{"award-number":["K23HL153759"]}]},{"name":"NIH NHLBI","award":["K24HL115354"],"award-info":[{"award-number":["K24HL115354"]}]},{"name":"NICHD","award":["T32HD060550"],"award-info":[{"award-number":["T32HD060550"]}]}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["Thorax"],"published-print":{"date-parts":[[2023,11]]},"abstract":"<jats:p>Excess mortality risk imparted by acute respiratory failure in children is unknown. We determined excess mortality risk associated with mechanically ventilated acute respiratory failure in pediatric sepsis. Novel ICD10-based algorithms were derived and validated to identify a surrogate for acute respiratory distress syndrome to calculate excess mortality risk. Algorithm-identified ARDS was identified with specificity of 96.7% (CI 93.0 \u2212 98.9) and sensitivity of 70.5% (CI 44.0 \u2013 89.7). Excess risk of mortality for ARDS was 24.4% (CI 22.9 \u2013 26.2). 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