{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T17:37:01Z","timestamp":1793813821078,"version":"4.6.1"},"reference-count":12,"publisher":"BMJ","issue":"10","funder":[{"DOI":"10.13039\/501100000272","name":"NIHR","doi-asserted-by":"crossref","award":["CL-2020-11-004"],"award-info":[{"award-number":["CL-2020-11-004"]}],"id":[{"id":"10.13039\/501100000272","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["Thorax"],"published-print":{"date-parts":[[2023,10]]},"abstract":"<jats:p>Pulmonary rehabilitation programmes including aerobic training improve cardiorespiratory fitness in patients with COPD, but the optimal programme design is unclear. We used random effects additive component network meta-analysis to investigate the relative effectiveness of different programme components on fitness measured by V\u0307O<jats:sub>2peak<\/jats:sub>in COPD. The included 59 studies involving 2191 participants demonstrated that V\u0307O<jats:sub>2peak<\/jats:sub>increased after aerobic training of at least moderate intensity with the greatest improvement seen following high intensity training. Lower limb aerobic training (SMD 0.56 95%\u2009CI 0.32;0.81, intervention arms=86) and the addition of non-invasive ventilation (SMD 0.55 95%\u2009CI 0.04;1.06, intervention arms=4) appeared to offer additional benefit but there was limited evidence for effectiveness of other exercise and non-exercise components.<\/jats:p>","DOI":"10.1136\/thorax-2023-220071","type":"journal-article","created":{"date-parts":[[2023,6,1]],"date-time":"2023-06-01T17:20:59Z","timestamp":1685640059000},"page":"1035-1038","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":12,"title":["Understanding the effectiveness of different exercise training programme designs on V\u0307O<sub>2peak<\/sub>in COPD: a component network meta-analysis"],"prefix":"10.1136","volume":"78","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2748-4063","authenticated-orcid":false,"given":"Thomas JC","family":"Ward","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charles D","family":"Plumptre","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandra V","family":"Fraser-Pye","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1369-8981","authenticated-orcid":false,"given":"Thomas E","family":"Dolmage","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amy V","family":"Jones","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5578-6408","authenticated-orcid":false,"given":"Ruth","family":"Trethewey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3561-438X","authenticated-orcid":false,"given":"Lorna","family":"Latimer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sally J","family":"Singh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin R","family":"Lindley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael C","family":"Steiner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1667-868X","authenticated-orcid":false,"given":"Rachael A","family":"Evans","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2023,6,1]]},"reference":[{"key":"2024051409142710000_78.10.1035.1","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/j.chest.2020.01.053","article-title":"Change in V'O2Peak in response to aerobic exercise training and the relationship with exercise prescription in people with COPD: A systematic review and meta-analysis","volume":"158","author":"Ward","year":"2020","journal-title":"Chest"},{"key":"2024051409142710000_78.10.1035.2","doi-asserted-by":"crossref","unstructured":"Holland AE , Singh SJ , Casaburi R . 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