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The increase in AHR was of a similar magnitude to that seen for <jats:italic>Alternaria<\/jats:italic> sensitised asthmatics and was primarily evident among those who were overweight or obese. In contrast, there was no significant association between early sensitisation to aeroallergens other than <jats:italic>Alternaria<\/jats:italic> and AHR among non-asthmatics. Why this group of <jats:italic>Alternaria<\/jats:italic> sensitised individuals without asthma demonstrated increased AHR of a magnitude similar to asthmatics is unknown and requires further investigation.<\/jats:p>","DOI":"10.1136\/thoraxjnl-2017-210325","type":"journal-article","created":{"date-parts":[[2018,3,21]],"date-time":"2018-03-21T16:15:42Z","timestamp":1521648942000},"page":"1170-1173","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":5,"title":["<i>Alternaria<\/i> sensitisation at age 6 years is associated with subsequent airway hyper-responsiveness in non-asthmatics"],"prefix":"10.1136","volume":"73","author":[{"given":"Anunya","family":"Hiranrattana","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Debra 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