{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,11,11]],"date-time":"2023-11-11T16:15:51Z","timestamp":1699719351763},"reference-count":11,"publisher":"BMJ","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Thorax"],"published-print":{"date-parts":[[1972,7,1]]},"DOI":"10.1136\/thx.27.4.429","type":"journal-article","created":{"date-parts":[[2008,12,13]],"date-time":"2008-12-13T02:58:29Z","timestamp":1229137109000},"page":"429-432","source":"Crossref","is-referenced-by-count":7,"title":["Clinical trial of bromhexine in severe chronic bronchitics during winter"],"prefix":"10.1136","volume":"27","author":[{"given":"S. W.","family":"Clarke","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G. M.","family":"Craig","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E. J. B.","family":"Makin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","reference":[{"key":"ref_1","first-page":"284","article-title":"On the expectorant activity of Bisolvon. Arch","volume":"163","author":"Boyd, E.M.; Sheppard, P.","year":"1966","unstructured":"Boyd, E. M., and Sheppard, P. (1966). On the expectorant activity of Bisolvon. Arch. int. Pharmacodyn, 163, 284.","journal-title":"Pharmacodyn"},{"key":"ref_2","first-page":"48","article-title":"Mucolytic treatment of chronic bronchitis during two winter periods","volume":"52","author":"Christensen, S.B.; Kjer, J.; Ryskjaer, S.; Arseth-Hansen, P.; Christensen, F.","year":"1971","unstructured":"Christensen, S. B., Kjer, J., Ryskjaer, S., Arseth-Hansen, P., and Christensen, F. (1971). Mucolytic treatment of chronic bronchitis during two winter periods. Scand. J. resp. Dis., 52, 48.","journal-title":"Scand. J. resp. Dis"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1152\/jappl.1970.29.4.464","article-title":"Resistance to two-phase gas-liquid flow in airways","volume":"29","author":"Clarke, S.W.; Jones, J.G.; Oliver, D.R.","year":"1970","unstructured":"Clarke, S. W., Jones, J. G., and Oliver, D. R. (1970). Resistance to two-phase gas-liquid flow in airways. J. appi. Physiol., 29, 464.","journal-title":"J. appi. Physiol"},{"key":"ref_4","first-page":"474","article-title":"Pharmakologische Untersuchungen uber eine Substanz mit sekretolytischer Wirkung","volume":"13","author":"Engelhorn, R.; Piischmann, S.","year":"1963","unstructured":"Engelhorn, R., and Piischmann, S. (1963). Pharmakologische Untersuchungen uber eine Substanz mit sekretolytischer Wirkung. Arzneimittel-Forsch., 13, 474.","journal-title":"Arzneimittel-Forsch"},{"key":"ref_5","first-page":"1094","article-title":"Effect of bromhexine on ventilatory capacity in patients with a variety of chest diseases","volume":"2","author":"Gent, M.; Knowlson, P.A.; Prime, F.J.","year":"1969","unstructured":"Gent, M., Knowlson, P. A., and Prime, F. J. (1969). Effect of bromhexine on ventilatory capacity in patients with a variety of chest diseases. Lancet, 2, 1094.","journal-title":"Lancet"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1136\/bmj.3.5717.260","article-title":"Expectorant action of bromhexine in chronic obstructive bronchitis","volume":"3","author":"Hamilton, W.F.D.; Palmer, K.N.V.; Gent, M.","year":"1970","unstructured":"Hamilton, W. F. D., Palmer, K. N. V., and Gent, M. (1970). Expectorant action of bromhexine in chronic obstructive bronchitis. Brit. med. J., 3, 260.","journal-title":"Brit. med. J"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1136\/thx.22.1.88","article-title":"The dynamics of cough in health and in chronic bronchitis","volume":"22","author":"Langlands, J.","year":"1967","unstructured":"Langlands, J. (1967). The dynamics of cough in health and in chronic bronchitis. Thorax, 22, 88.","journal-title":"Thorax"},{"key":"ref_8","first-page":"448","article-title":"Double-blind clinical trial of bromhexine as a mucolytic drug in chronic bronchitis","volume":"1","unstructured":", (1970). Double-blind clinical trial of bromhexine as a mucolytic drug in chronic bronchitis. Lancet, 1, 448.","journal-title":"Lancet"},{"key":"ref_9","first-page":"775","article-title":"Definition and classification ofchronic bronchitis for clinical and epidemiological purposes","volume":"1","author":"Council, Medical Research","year":"1965","unstructured":"Medical Research Council (1965). Definition and classification ofchronic bronchitis for clinical and epidemiological purposes. Lancet, 1, 775.","journal-title":"Lancet"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1042\/cs0380145","article-title":"The viscosity of bronchial secretion","volume":"38","author":"Sturgess, J.M.; Palfrey, A.J.; Reid, L.","year":"1970","unstructured":"Sturgess, J. M., Palfrey, A. J., and Reid, L. (1970). The viscosity of bronchial secretion. Clin. Sci., 38, 145.","journal-title":"Clin. Sci"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1177\/003693307101600505","article-title":"The use of a drug marker in a clinical trial","volume":"16","author":"Thompson, R.H.; Stowers, J.M.","year":"1971","unstructured":"Thompson, R. H., and Stowers, J. M. (1971). The use of a drug marker in a clinical trial. Scot. med. J., 16, 259.","journal-title":"Scot. med. J"}],"container-title":["Thorax"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/thx.27.4.429","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,9,26]],"date-time":"2020-09-26T09:25:52Z","timestamp":1601112352000},"score":1,"resource":{"primary":{"URL":"https:\/\/thorax.bmj.com\/lookup\/doi\/10.1136\/thx.27.4.429"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1972,7,1]]},"references-count":11,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1972,7,1]]}},"URL":"https:\/\/doi.org\/10.1136\/thx.27.4.429","relation":{},"ISSN":["0040-6376"],"issn-type":[{"value":"0040-6376","type":"print"}],"subject":[],"published":{"date-parts":[[1972,7,1]]}}}