{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T12:29:01Z","timestamp":1791203341911,"version":"4.2.0"},"reference-count":18,"publisher":"BMJ","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Thorax"],"published-print":{"date-parts":[[1974,7,1]]},"DOI":"10.1136\/thx.29.4.401","type":"journal-article","created":{"date-parts":[[2008,12,13]],"date-time":"2008-12-13T02:58:29Z","timestamp":1229137109000},"page":"401-406","source":"Crossref","is-referenced-by-count":23,"title":["A controlled trial of prednisone, in low dosage, in patients with chronic airways obstruction"],"prefix":"10.1136","volume":"29","author":[{"given":"J. A.","family":"Evans","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I. M.","family":"Morrison","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K. B.","family":"Saunders","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1056\/NEJM196301312680502","article-title":"A controlled study of the effect of prednisone on air-flow obstruction in severe pulmonary emphysema","volume":"268","author":"Beerel, F.; Jick, H.; Tyler, J.M.","year":"1963","unstructured":"Beerel, F., Jick, H., and Tyler, J. M. (1963). A controlled study of the effect of prednisone on air-flow obstruction in severe pulmonary emphysema. New England Journal of Medicine, 268, 226.","journal-title":"New England Journal of Medicine"},{"key":"ref_2","first-page":"264","article-title":"Prednisone treatment for stable pulmonary emphysema","volume":"104","author":"Beerel, F.R.; Vance, J.W.","year":"1971","unstructured":"Beerel, F. R. and Vance, J. W. (1971). Prednisone treatment for stable pulmonary emphysema. American Review of Respiratory Disease, 104, 264.","journal-title":"American Review of Respiratory Disease"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"1279","DOI":"10.1172\/JCI103715","article-title":"The relationship between airway resistance, airway conductance and lung volume in subjects of different age and body size","volume":"37","author":"Briscoe, W.A.; Dubois, A.B.","year":"1958","unstructured":"Briscoe, W. A. and Dubois, A. B. (1958). The relationship between airway resistance, airway conductance and lung volume in subjects of different age and body size. Journal of Clinical Investigation, 37, 1279.","journal-title":"Journal of Clinical Investigation"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"1311","DOI":"10.1016\/S0140-6736(62)92418-2","article-title":"Steroid therapy in chronic bronchitis","volume":"1","author":"Clifton, M.; Stuart-Harris, C.H.","year":"1962","unstructured":"Clifton, M. and Stuart-Harris, C. H. (1962). Steroid therapy in chronic bronchitis. Lancet, 1, 1311.","journal-title":"Lancet"},{"key":"ref_5","first-page":"39","article-title":"Bellows spirometer and transistor timer for the measurement of forced expiratory volume and vital capacity","volume":"172","author":"Collins, M.M.; McDermott, M.; McDermott, T.J.","year":"1964","unstructured":"Collins, M. M., McDermott, M., and McDermott, T. J. (1964). Bellows spirometer and transistor timer for the measurement of forced expiratory volume and vital capacity. Journal of Physiology, 172, 39P.","journal-title":"Journal of Physiology"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1097\/00000441-196110000-00006","article-title":"Triamcinolone in the therapy of chronic bronchitis and pulmonary emphysema","volume":"242","author":"Corazza, L.J.; Morrow, C.S.; Chesney, T.A.","year":"1961","unstructured":"Corazza, L. J., Morrow, C. S., and Chesney, T. A. (1961). Triamcinolone in the therapy of chronic bronchitis and pulmonary emphysema. American Journal of Medical Science, 242, 436.","journal-title":"American Journal of Medical Science"},{"key":"ref_7","article-title":"Lung Function, Chapter 14","author":"Cotes, J.E.","year":"1965","unstructured":"Cotes, J. E. (1965). Lung Function, Chapter 14. Blackwell Scientific Publications, Oxford."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1172\/JCI103281","article-title":"A rapid plethysmographic method for measuring thoracic gas volume: a comparison with a nitrogen washout method for measuring functional residual capacity in normal subjects","volume":"35","author":"Dubois, A.B.; Botelho, S.Y.; Bedell, G.N.; Marshall, R.; H, Comroe J.","year":"1956","unstructured":"Dubois, A. B., Botelho, S. Y., Bedell, G. N., Marshall, R., and Comroe J. H. (1956a). A rapid plethysmographic method for measuring thoracic gas volume: a comparison with a nitrogen washout method for measuring functional residual capacity in normal subjects. Journal of Clinical Investigation, 35, 322.","journal-title":"Journal of Clinical Investigation"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1172\/JCI103282","article-title":"A new method for measuring airway resistance in man using a body plethysmograph; values in normal subjects and in patients with respiratory disease","volume":"35","author":"Comroe, J.H.","year":"1956","unstructured":"_,__ and Comroe, J. H. (1956b). A new method for measuring airway resistance in man using a body plethysmograph; values in normal subjects and in patients with respiratory disease. Journal of Clinical Investigation, 35, 327.","journal-title":"Journal of Clinical Investigation"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1042\/cs044026Pb","article-title":"Double blind trial of prednisone, in low dose, in patients with chronic airways obstruction","volume":"44","author":"Evans, J.A.; Morrison, I.M.; Saunders, K.B.","year":"1973","unstructured":"Evans, J. A., Morrison, I. M., and Saunders, K. B. (1973). Double blind trial of prednisone, in low dose, in patients with chronic airways obstruction. Clinical Science, 44, 26P.","journal-title":"Clinical Science"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"774","DOI":"10.1056\/NEJM195804172581602","article-title":"Bronchodilators and corticosteroids in the treatment of obstructive pulmonary emphysema","volume":"258","author":"Franklin, W.; Michelson, A.L.; Lowell, F.C.; Schiller, I.W.","year":"1958","unstructured":"Franklin, W., Michelson, A. L., Lowell, F. C., and Schiller, I. W. (1958). Bronchodilators and corticosteroids in the treatment of obstructive pulmonary emphysema. New England Journal of Medicine, 258, 774.","journal-title":"New England Journal of Medicine"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"1509","DOI":"10.1136\/bmj.2.5371.1509","article-title":"Bronchodilators and corticosteroids in chronic bronchitis and emphysema","volume":"2","author":"Freedman, B.J.","year":"1963","unstructured":"Freedman, B. J. (1963). Bronchodilators and corticosteroids in chronic bronchitis and emphysema. British Medical Journal, 2, 1509.","journal-title":"British Medical Journal"},{"key":"ref_13","first-page":"678","article-title":"Effect of corticosteroids on pulmonary function in chronic bronchitis with airway obstruction","volume":"96","author":"Fuleihan, F.J.D.; Feisal, K.A.; Malouf, N.N.","year":"1967","unstructured":"Fuleihan, F. J. D., Feisal, K. A., and Malouf, N. N. (1967). Effect of corticosteroids on pulmonary function in chronic bronchitis with airway obstruction. American Review of Respiratory Disease, 96, 678.","journal-title":"American Review of Respiratory Disease"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"750","DOI":"10.1259\/0007-1285-35-419-750","article-title":"Emphysema and the chest film: a retrospective radiological and pathological study","volume":"35","author":"Laws, J.W.; Heard, B.E.","year":"1962","unstructured":"Laws, J. W. and Heard, B. E. (1962). Emphysema and the chest film: a retrospective radiological and pathological study. British Journal of Radiology, 35, 750.","journal-title":"British Journal of Radiology"},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1164\/arrd.1963.87.4.529","article-title":"Evaluation of methods used in detecting changes of airways resistance in man","volume":"87","author":"Lloyd, Jr., T.C.; Wright, G.W.","year":"1963","unstructured":"Lloyd, T. C. Jr. and Wright, G. W. (1963). Evaluation of methods used in detecting changes of airways resistance in man. American Review of Respiratory Diseases, 87, 529.","journal-title":"American Review of Respiratory Diseases"},{"key":"ref_16","first-page":"1187","article-title":"Longtetracycline and prednisolone in chronic bronchitis: a controlled trial","volume":"2","author":"A.","year":"1957","unstructured":"A. (1957). Longtetracycline and prednisolone in chronic bronchitis: a controlled trial. Lancet, 2, 1187.","journal-title":"Lancet"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1016\/S0140-6736(68)92829-8","article-title":"Airways obstruction before and after isoprenaline, histamine, and prednisolone in patients with chronic obstructive bronchitis","volume":"1","author":"Oppenheimer, E.A.; Rigatto, M.; Fletcher, C.M.","year":"1968","unstructured":"Oppenheimer, E. A., Rigatto, M., and Fletcher, C. M. (1968). Airways obstruction before and after isoprenaline, histamine, and prednisolone in patients with chronic obstructive bronchitis. Lancet, 1, 552.","journal-title":"Lancet"},{"key":"ref_18","first-page":"257","article-title":"Evauluation of spirometric methods used to assess abnormalities in airway resistance","volume":"93","author":"Stein, M.; Tanabe, G.; Rege, V.; Khan, M.","year":"1966","unstructured":"Stein, M., Tanabe, G., Rege, V., and Khan, M. (1966). Evauluation of spirometric methods used to assess abnormalities in airway resistance. American Review of Respiratory Diseases, 93, 257.","journal-title":"American Review of Respiratory Diseases"}],"container-title":["Thorax"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/thx.29.4.401","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,9,26]],"date-time":"2020-09-26T09:27:40Z","timestamp":1601112460000},"score":1,"resource":{"primary":{"URL":"https:\/\/thorax.bmj.com\/lookup\/doi\/10.1136\/thx.29.4.401"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1974,7,1]]},"references-count":18,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1974,7,1]]}},"URL":"https:\/\/doi.org\/10.1136\/thx.29.4.401","relation":{},"ISSN":["0040-6376"],"issn-type":[{"value":"0040-6376","type":"print"}],"subject":[],"published":{"date-parts":[[1974,7,1]]}}}