{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,16]],"date-time":"2025-10-16T13:51:57Z","timestamp":1760622717685},"reference-count":9,"publisher":"BMJ","issue":"8","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Thorax"],"published-print":{"date-parts":[[1989,8,1]]},"DOI":"10.1136\/thx.44.8.678","type":"journal-article","created":{"date-parts":[[2008,12,13]],"date-time":"2008-12-13T03:22:59Z","timestamp":1229138579000},"page":"678-679","source":"Crossref","is-referenced-by-count":19,"title":["Locally invasive pulmonary aspergillosis occurring in a gardener: an occupational hazard?"],"prefix":"10.1136","volume":"44","author":[{"given":"J A","family":"Zuk","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D","family":"King","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H D","family":"Zakhour","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J C","family":"Delaney","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","reference":[{"key":"ref_1","article-title":"Aspergillus lung disease takes several forms, these being allergic reactions or saprophytic and invasive infections.'","volume-title":"these forms, invasive pulmonary aspergillosis is least common, normally occurring in abnormal lungs (for example, cysts, old tuberculous cavities) or in association with leukaemia, lymphoma, and carcinoma and in patients having high dose corticosteroid or cytotoxic treatment-that is, in the immunocompromised host.23 Our patient had none of these predisposing factors; he had previously normal lungs and no evidence of an immunocompromised state. This was therefore a case of fatal, locally invasive pulmonary aspergillosis due to Afumigatus. In the past 30 years only one similar case in an adult has been described,4 this having been caused by Aspergillus niger. Six almost identical cases caused by Afumigatus have, however, been reported in children.5 All were in children living in an agricultural environment, where the causative organism is frequently found in large numbers","author":"Of all","unstructured":"Aspergillus lung disease takes several forms, these being allergic reactions or saprophytic and invasive infections.' Of all these forms, invasive pulmonary aspergillosis is least common, normally occurring in abnormal lungs (for example, cysts, old tuberculous cavities) or in association with leukaemia, lymphoma, and carcinoma and in patients having high dose corticosteroid or cytotoxic treatment-that is, in the immunocompromised host.23 Our patient had none of these predisposing factors; he had previously normal lungs and no evidence of an immunocompromised state. This was therefore a case of fatal, locally invasive pulmonary aspergillosis due to Afumigatus. In the past 30 years only one similar case in an adult has been described,4 this having been caused by Aspergillus niger. Six almost identical cases caused by Afumigatus have, however, been reported in children.5 All were in children living in an agricultural environment, where the causative organism is frequently found in large numbers."},{"key":"ref_2","first-page":"206","article-title":"Aspergillus lung disease","volume":"20","author":"IJ, I.Gordon; CC, Evans","year":"1986","unstructured":"I Gordon IJ, Evans CC. Aspergillus lung disease. J R Coll Physicians Lond 1986;20:206-1 I.","journal-title":"J R Coll Physicians Lond"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1097\/00005792-197003000-00002","article-title":"The spectrum of disease in 98 patients","volume":"49","author":"Young, R.C.; Bennett, J.E.; Vogel, C.L.; Carbone, P.P.; Aspergillosis, DeVita V.T.","year":"1970","unstructured":"Young RC, Bennett JE, Vogel CL, Carbone PP, DeVita VT. Aspergillosis. The spectrum of disease in 98 patients. Medicine (Baltimore) 1970;49:147-73.","journal-title":"Medicine (Baltimore)"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1378\/chest.59.1.28","article-title":"Aspergillosis of the lungan eighteen year experience","volume":"59","author":"Aslam, P.A.; Eastridge, C.E.; Hughes, F.A.","year":"1971","unstructured":"Aslam PA, Eastridge CE, Hughes FA. Aspergillosis of the lungan eighteen year experience. Chest 1971;59:28-32.","journal-title":"Chest"},{"issue":"81","key":"ref_5","first-page":"392","article-title":"Pulmonary aspergillosis","volume":"1960","author":"Toigo, A.","unstructured":"Toigo A. Pulmonary aspergillosis. Am Rev Respir Dis 1960;81:392-6.","journal-title":"Am Rev Respir Dis"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1136\/adc.41.215.34","article-title":"Fatal acute pulmonary aspergillosis in two children ofone family","volume":"41","author":"Strelling, M.K.; Rhaney, K.; Simmons, A.R.; Thomson, J.","year":"1966","unstructured":"Strelling MK, Rhaney K, Simmons AR, Thomson J. Fatal acute pulmonary aspergillosis in two children ofone family. Arch Dis Child 1966;41:34-43.","journal-title":"Arch Dis Child"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1128\/JCM.11.4.370-376.1980","article-title":"Significance of aspergillus species isolated from respiratory secretions in the diagnosis of invasive pulmonary aspergillosis","volume":"11","author":"Nalesnik, M.A.; Myerowitz, R.L.; Jenkins, R.; Lenkey, J.; Herbert, D.","year":"1980","unstructured":"Nalesnik MA, Myerowitz RL, Jenkins R, Lenkey J, Herbert D. Significance of aspergillus species isolated from respiratory secretions in the diagnosis of invasive pulmonary aspergillosis. J Clin Microbiol 1980;11:370-6.","journal-title":"J Clin Microbiol"},{"key":"ref_8","first-page":"799","article-title":"The general and specific humoral immune response to pulmonary aspergillosis","volume":"112","author":"Bardana, E.J.; Gerber, J.D.; Craig, S.; Cianciull, F.D.","year":"1975","unstructured":"Bardana EJ, Gerber JD, Craig S, Cianciull FD. The general and specific humoral immune response to pulmonary aspergillosis. Am Rev Respir Dis 1975;112:799-805.","journal-title":"Am Rev Respir Dis"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"2019","DOI":"10.1002\/1097-0142(197810)42:4<2019::AID-CNCR2820420451>3.0.CO;2-B","article-title":"Recognition and successful management of pulmonary aspergillosis in leukaemia","volume":"42","author":"Sinclair, A.J.; RossofAH, Coltman; C.A.","year":"1978","unstructured":"Sinclair AJ, RossofAH, Coltman CA. Recognition and successful management of pulmonary aspergillosis in leukaemia. Cancer 1978;42:2019-24.","journal-title":"Cancer"}],"container-title":["Thorax"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/thx.44.8.678","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,9,26]],"date-time":"2020-09-26T09:09:02Z","timestamp":1601111342000},"score":1,"resource":{"primary":{"URL":"https:\/\/thorax.bmj.com\/lookup\/doi\/10.1136\/thx.44.8.678"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1989,8,1]]},"references-count":9,"journal-issue":{"issue":"8","published-print":{"date-parts":[[1989,8,1]]}},"URL":"https:\/\/doi.org\/10.1136\/thx.44.8.678","relation":{},"ISSN":["0040-6376"],"issn-type":[{"value":"0040-6376","type":"print"}],"subject":[],"published":{"date-parts":[[1989,8,1]]}}}